Alpk1 (alpha kinase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Alpk1 (alpha kinase 1) Chinchilla lanigera
Analyze
Symbol: Alpk1
Name: alpha kinase 1
RGD ID: 9024278
Description: ENCODES a protein that exhibits monosaccharide binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cilium assembly (ortholog); cytoplasmic pattern recognition receptor signaling pathway (ortholog); innate immune response (ortholog); ASSOCIATED WITH aniridia (ortholog); Axenfeld-Rieger syndrome type 1 (ortholog); diabetes mellitus (ortholog); FOUND IN centrosome (ortholog); cilium (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alpha-kinase 1; alpha-protein kinase 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545714,325,281 - 14,379,937 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545714,325,278 - 14,444,368 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Alpk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545714,325,281 - 14,379,937 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545714,325,278 - 14,444,368 (-)NCBIChiLan1.0ChiLan1.0
ALPK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384112,297,369 - 112,442,621 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4112,285,509 - 112,442,621 (+)EnsemblGRCh38hg38GRCh38
GRCh374113,218,525 - 113,363,777 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364113,437,948 - 113,583,223 (+)NCBINCBI36Build 36hg18NCBI36
Build 344113,656,455 - 113,720,433NCBI
Celera4110,512,576 - 110,657,856 (+)NCBICelera
Cytogenetic Map4q25NCBI
HuRef4108,950,042 - 109,095,428 (+)NCBIHuRef
CHM1_14113,195,311 - 113,340,525 (+)NCBICHM1_1
T2T-CHM13v2.04115,605,712 - 115,750,965 (+)NCBIT2T-CHM13v2.0
Alpk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393127,460,367 - 127,574,195 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3127,463,959 - 127,574,176 (-)EnsemblGRCm39 Ensembl
GRCm383127,666,718 - 127,780,547 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3127,670,310 - 127,780,527 (-)EnsemblGRCm38mm10GRCm38
MGSCv373127,373,228 - 127,483,445 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363127,662,332 - 127,772,549 (-)NCBIMGSCv36mm8
Celera3134,160,957 - 134,282,674 (-)NCBICelera
Cytogenetic Map3G2NCBI
cM Map356.54NCBI
Alpk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82218,801,425 - 218,924,013 (-)NCBIGRCr8
mRatBN7.22216,126,939 - 216,247,180 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2216,128,825 - 216,247,157 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.02231,997,360 - 232,117,471 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2231,996,088 - 232,117,134 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02251,345,268 - 251,462,165 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42224,934,194 - 224,989,819 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12224,888,846 - 224,988,527 (-)NCBI
Celera2208,443,568 - 208,559,107 (-)NCBICelera
Cytogenetic Map2q42NCBI
ALPK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23110,372,767 - 110,517,166 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14110,666,192 - 110,813,772 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04104,786,721 - 104,931,981 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14115,349,826 - 115,495,026 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4115,430,258 - 115,495,026 (+)Ensemblpanpan1.1panPan2
ALPK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13232,135,110 - 32,270,732 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3232,136,738 - 32,267,264 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha329,763,410 - 9,897,996 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03232,358,805 - 32,493,869 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3232,364,919 - 32,493,694 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13232,341,883 - 32,476,840 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03232,102,803 - 32,237,847 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0327,622,218 - 7,758,515 (-)NCBIUU_Cfam_GSD_1.0
Alpk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053018,612,620 - 8,737,685 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365633,235,181 - 3,296,257 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365633,233,913 - 3,296,671 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALPK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8110,241,619 - 110,367,912 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18110,241,220 - 110,368,001 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28118,153,267 - 118,184,844 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALPK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1760,096,755 - 60,233,569 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl760,202,204 - 60,236,743 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603738,857,444 - 38,994,232 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Alpk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248386,229,899 - 6,287,920 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248386,273,398 - 6,288,363 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000007598   ⟹   ENSCLAP00000007481
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545714,325,281 - 14,379,937 (-)Ensembl
RefSeq Acc Id: XM_005397100   ⟹   XP_005397157
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545714,325,278 - 14,444,368 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013520771   ⟹   XP_013376225
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545714,325,278 - 14,444,368 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013520772   ⟹   XP_013376226
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545714,325,278 - 14,444,368 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005397157 (Get FASTA)   NCBI Sequence Viewer  
  XP_013376225 (Get FASTA)   NCBI Sequence Viewer  
  XP_013376226 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007481
  ENSCLAP00000007481.1
Reference Protein Sequences
RefSeq Acc Id: XP_005397157   ⟸   XM_005397100
- UniProtKB: A0A8C2V447 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013376226   ⟸   XM_013520772
- UniProtKB: A0A8C2V447 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013376225   ⟸   XM_013520771
- UniProtKB: A0A8C2V447 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000007481   ⟸   ENSCLAT00000007598
Protein Domains
Alpha-type protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005257 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007598 ENTREZGENE
  ENSCLAT00000007598.1 UniProtKB/TrEMBL
Gene3D-CATH MHCK/EF2 kinase UniProtKB/TrEMBL
InterPro ALPK1 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  MHCK_EF2_kinase UniProtKB/TrEMBL
NCBI Gene Alpk1 ENTREZGENE
PANTHER ALPHA-PROTEIN KINASE 1 UniProtKB/TrEMBL
  PTHR46747 UniProtKB/TrEMBL
Pfam Alpha_kinase UniProtKB/TrEMBL
PROSITE ALPHA_KINASE UniProtKB/TrEMBL
SMART Alpha_kinase UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2V447 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Alpk1  alpha kinase 1    alpha-kinase 1  Symbol and/or name change 5135510 APPROVED