Fkbp14 (FKBP prolyl isomerase 14)

Gene: Fkbp14 (FKBP prolyl isomerase 14) Chinchilla lanigera

Analyze

Symbol:

Fkbp14

Name:

FKBP prolyl isomerase 14

RGD ID:

9022945

Description:

ASSOCIATED WITH congenital muscular dystrophy (ortholog); Ehlers-Danlos syndrome (ortholog); Ehlers-Danlos syndrome kyphoscoliotic type 2 (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

FK506 binding protein 14; FK506 binding protein 14, 22 kDa; peptidyl-prolyl cis-trans isomerase FKBP14

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955410	31,309,525 - 31,325,544 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955410	31,313,637 - 31,325,544 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital muscular dystrophy (ISO)

Ehlers-Danlos syndrome (ISO)

Ehlers-Danlos syndrome kyphoscoliotic type 2 (ISO)

Joint Instability (ISO)

Muscle Hypotonia (ISO)

pleomorphic xanthoastrocytoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Fkbp14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955410	31,309,525 - 31,325,544 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955410	31,313,637 - 31,325,544 (-)	NCBI	ChiLan1.0	ChiLan1.0

FKBP14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	30,005,923 - 30,026,702 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	30,010,587 - 30,026,702 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	30,050,203 - 30,066,318 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	30,019,409 - 30,032,793 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	29,826,123 - 29,839,508	NCBI
Celera	7	30,042,275 - 30,055,659 (-)	NCBI		Celera
Cytogenetic Map	7	p14.3	NCBI
HuRef	7	29,932,008 - 29,948,256 (-)	NCBI		HuRef
CHM1_1	7	30,050,309 - 30,066,527 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	30,143,627 - 30,164,384 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	30,100,028 - 30,116,246 (-)	NCBI

Fkbp14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	54,554,590 - 54,574,329 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	54,554,589 - 54,574,293 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	54,577,602 - 54,597,344 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	54,577,604 - 54,597,308 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	54,527,599 - 54,543,122 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	54,507,183 - 54,522,706 (-)	NCBI		MGSCv36	mm8
Celera	6	55,106,438 - 55,121,956 (-)	NCBI		Celera
Cytogenetic Map	6	B3	NCBI
cM Map	6	27.01	NCBI

Fkbp14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	85,035,840 - 85,051,917 (-)	NCBI		GRCr8
mRatBN7.2	4	83,705,531 - 83,721,515 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	83,705,652 - 83,721,528 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	88,922,395 - 88,935,651 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	84,697,822 - 84,711,077 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	83,116,557 - 83,131,174 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	84,753,628 - 84,768,314 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	84,753,633 - 84,768,249 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	149,413,598 - 149,428,281 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	82,985,646 - 83,000,392 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	83,270,270 - 83,285,014 (-)	NCBI
Celera	4	78,576,056 - 78,590,677 (-)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

FKBP14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	34,828,200 - 34,845,932 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	83,152,932 - 83,170,633 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	30,641,413 - 30,656,507 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	30,758,165 - 30,772,640 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	30,758,165 - 30,772,640 (-)	Ensembl	panpan1.1		panPan2

Fkbp14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	87,084,892 - 87,098,691 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	6,294,183 - 6,310,445 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936478	6,296,598 - 6,310,405 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FKBP14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	42,903,100 - 42,913,609 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	42,903,100 - 42,913,609 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	47,295,898 - 47,305,208 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FKBP14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	28,352,196 - 28,367,910 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	28,352,402 - 28,367,147 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	76,325,433 - 76,339,220 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fkbp14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624739	770,808 - 781,949 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624739	770,775 - 791,251 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005377493	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01011321	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCE01159547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000015844 ⟹ ENSCLAP00000015682

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955410	31,309,525 - 31,325,544 (-)	Ensembl

RefSeq Acc Id:

XM_005377493 ⟹ XP_005377550

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955410	31,313,637 - 31,325,544 (-)	NCBI

Sequence:

show sequence

TTTGGGTTTAACTCTTTAATGTGAGTTTGCAAAGCGTGGGAAAGTTGTTGGTAGTAAAAGTGCC
ACGTCTCCTAAGAGGGAGAGTCCTGAGCTTGCCAGAGGCCGTTGTCCCTAAGCCTACAACTGAG
TTTTTAACTCTATGCAGTCGGGGCCTTTTCTCTTTTCGTAGTGACTTCTTTCTAGCGTCAGTAA
CATGAGGTTTCTCTTGTGGAACTCGATCTTGACGTTGTTAATCACGGCTTTGAGTGGAGCTCTG
ATCCCCGAGCCAGAAGTGAAAATTGAAGTTCTCCAGAAGCCATTCATCTGCCATCGGAAGACCA
AAGGAGGGGATTTGATGTTGGTCCACTATGAGGGCTACTTAGAAAAAGATGGCTCCTTATTTCA
CTCCACTCACAAACATAACAATGGTCAGCCAATTTGGTTTACTCTGGGCATCCTGGAGGCACTC
AAAGGCTGGGACCGCGGCTTGAAAGGAATGTGTGTAGGAGAGAAGAGAAAGCTCACCATTCCTC
CTTCCCTGGGCTATGGGAAAGAAGGAAAAGGTAAAATCCCCCCAGAGAGCACATTGATATTCAA
CATTGACCTCTTGGAAATTCGAAATGGACCAAGATCCCATGAGTCATTCCAAGAAATGGATCTC
AATGATGACTGGAAACTCTCTAAACATGAGGTTAAAATGTATTTAAAGAAGGAGTTCGAAAAGC
ATGGTGCAGTAGTGAATGAAAGTCATCATGATGTTCTGGTGGAGGATATTTTTGATAAAGAAGA
TGAAGACAAAGATGGATTTATATCTGCCAGAGAATTTACATATCTACACGATGAGTTATAGTGC
TATCTTCACATTTTATATAGCATCTATCTTTAAAGAGAAGGCAATCGTCTTTAAAGAAAAAATT
TTTAAATGTTCTGTTTTTGCTTTTTAAAATGTTTATATTATTTTTCTGGCTATTATTTAAAGAA
CCCTTTAGGGTTTC

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Protein Sequences


Protein RefSeqs	XP_005377550	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000015682
	ENSCLAP00000015682.1

RefSeq Acc Id:

XP_005377550 ⟸ XM_005377493

- UniProtKB:

A0A8C2VHH8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRFLLWNSILTLLITALSGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFH
STHKHNNGQPIWFTLGILEALKGWDRGLKGMCVGEKRKLTIPPSLGYGKEGKGKIPPESTLIFN
IDLLEIRNGPRSHESFQEMDLNDDWKLSKHEVKMYLKKEFEKHGAVVNESHHDVLVEDIFDKED
EDKDGFISAREFTYLHDEL

hide sequence

RefSeq Acc Id:

ENSCLAP00000015682 ⟸ ENSCLAT00000015844

Protein Domains

EF-hand PPIase FKBP-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000010774	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000015844	ENTREZGENE
	ENSCLAT00000015844.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.50.40	UniProtKB/TrEMBL
	EF-hand	UniProtKB/TrEMBL
InterPro	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
	PPIase_dom_sf	UniProtKB/TrEMBL
	PPIase_FKBP_dom	UniProtKB/TrEMBL
NCBI Gene	Fkbp14	ENTREZGENE
PANTHER	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP14	UniProtKB/TrEMBL
	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14	UniProtKB/TrEMBL
Pfam	FKBP_C	UniProtKB/TrEMBL
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
	FKBP_PPIASE	UniProtKB/TrEMBL
Superfamily-SCOP	FKBP-like	UniProtKB/TrEMBL
	SSF47473	UniProtKB/TrEMBL
UniProt	A0A8C2VHH8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-11-06	Fkbp14	FKBP prolyl isomerase 14		FK506 binding protein 14	Symbol and/or name change	5135510	APPROVED
2016-08-16	Fkbp14	FK506 binding protein 14		FK506 binding protein 14, 22 kDa	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM