Tnpo2 (transportin 2) - Rat Genome Database

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Gene: Tnpo2 (transportin 2) Chinchilla lanigera
Analyze
Symbol: Tnpo2
Name: transportin 2
RGD ID: 8962167
Description: INVOLVED IN negative regulation of muscle cell differentiation (ortholog); protein import into nucleus (ortholog); ASSOCIATED WITH alpha-mannosidosis (ortholog); Charcot-Marie-Tooth disease dominant intermediate B (ortholog); episodic ataxia type 2 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transportin-2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,807,701 - 31,826,919 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,807,701 - 31,826,938 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tnpo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,807,701 - 31,826,919 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,807,701 - 31,826,938 (-)NCBIChiLan1.0ChiLan1.0
TNPO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381912,699,201 - 12,723,932 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1912,699,201 - 12,724,011 (-)EnsemblGRCh38hg38GRCh38
GRCh371912,810,015 - 12,834,746 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,671,015 - 12,694,078 (-)NCBINCBI36Build 36hg18NCBI36
Build 341912,671,014 - 12,694,078NCBI
Celera1912,699,722 - 12,724,521 (-)NCBICelera
Cytogenetic Map19p13.13NCBI
HuRef1912,383,321 - 12,408,047 (-)NCBIHuRef
CHM1_11912,810,514 - 12,835,309 (-)NCBICHM1_1
T2T-CHM13v2.01912,823,691 - 12,848,419 (-)NCBIT2T-CHM13v2.0
Tnpo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39885,763,502 - 85,784,214 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl885,763,544 - 85,784,212 (+)EnsemblGRCm39 Ensembl
GRCm38885,036,873 - 85,057,585 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,036,915 - 85,057,583 (+)EnsemblGRCm38mm10GRCm38
MGSCv37887,560,814 - 87,581,482 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36887,927,020 - 87,947,685 (+)NCBIMGSCv36mm8
Celera889,331,668 - 89,352,340 (+)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.51NCBI
Tnpo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81940,004,271 - 40,024,565 (-)NCBIGRCr8
mRatBN7.21923,099,398 - 23,119,696 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1923,099,401 - 23,119,596 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1929,922,018 - 29,941,905 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01930,576,382 - 30,596,269 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01932,799,067 - 32,818,953 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01926,149,671 - 26,171,812 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1926,151,900 - 26,171,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01937,127,523 - 37,147,431 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41924,755,689 - 24,775,599 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11924,762,264 - 24,780,697 (-)NCBI
Celera1922,657,366 - 22,677,276 (-)NCBICelera
Cytogenetic Map19q11NCBI
TNPO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22017,628,110 - 17,653,699 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11916,628,668 - 16,654,236 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01912,261,026 - 12,286,571 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11913,006,110 - 13,032,317 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1913,006,110 - 13,032,317 (-)Ensemblpanpan1.1panPan2
TNPO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12049,407,842 - 49,424,220 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2049,407,152 - 49,424,752 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2049,281,439 - 49,297,799 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02049,926,256 - 49,942,676 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2049,926,323 - 49,941,476 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12049,137,325 - 49,153,713 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02049,563,664 - 49,580,225 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02049,806,342 - 49,822,747 (+)NCBIUU_Cfam_GSD_1.0
Tnpo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118208,511,376 - 208,529,977 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366591,824,729 - 1,843,727 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366591,824,729 - 1,843,725 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNPO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl266,271,496 - 66,288,264 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1266,267,776 - 66,288,763 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2266,650,573 - 66,667,950 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNPO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1611,387,993 - 11,414,681 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl611,387,683 - 11,414,709 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660748,384,607 - 8,408,643 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnpo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624901334,154 - 352,060 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624901334,277 - 351,653 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000019782   ⟹   ENSCLAP00000019589
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541531,807,701 - 31,826,919 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000019783   ⟹   ENSCLAP00000019590
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541531,807,701 - 31,825,884 (-)Ensembl
RefSeq Acc Id: XM_005381021   ⟹   XP_005381078
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541531,807,701 - 31,826,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512350   ⟹   XP_013367804
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541531,807,701 - 31,826,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512351   ⟹   XP_013367805
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541531,807,701 - 31,825,884 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512352   ⟹   XP_013367806
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541531,807,701 - 31,826,938 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005381078   ⟸   XM_005381021
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YSA3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367806   ⟸   XM_013512352
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YS98 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367804   ⟸   XM_013512350
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YS98 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367805   ⟸   XM_013512351
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YS98 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000019590   ⟸   ENSCLAT00000019783
RefSeq Acc Id: ENSCLAP00000019589   ⟸   ENSCLAT00000019782
Protein Domains
Importin N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013442 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019782 ENTREZGENE
  ENSCLAT00000019782.1 UniProtKB/TrEMBL
  ENSCLAT00000019783 ENTREZGENE
  ENSCLAT00000019783.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  HEAT UniProtKB/TrEMBL
  Importin-beta_N UniProtKB/TrEMBL
  Importin_beta UniProtKB/TrEMBL
NCBI Gene Tnpo2 ENTREZGENE
PANTHER PTHR10527 UniProtKB/TrEMBL
  TRANSPORTIN-2 UniProtKB/TrEMBL
Pfam HEAT UniProtKB/TrEMBL
  HEAT_EZ UniProtKB/TrEMBL
  IBN_N UniProtKB/TrEMBL
PROSITE IMPORTIN_B_NT UniProtKB/TrEMBL
SMART IBN_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8C2YS98 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YSA3 ENTREZGENE, UniProtKB/TrEMBL