Pls3 (plastin 3) - Rat Genome Database

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Gene: Pls3 (plastin 3) Chinchilla lanigera
Analyze
Symbol: Pls3
Name: plastin 3
RGD ID: 8946074
Description: ENCODES a protein that exhibits structural constituent of presynaptic actin cytoskeleton (ortholog); INVOLVED IN bone development (ortholog); inner ear auditory receptor cell differentiation (ortholog); regulation of synaptic vesicle cycle (ortholog); PARTICIPATES IN auditory mechanotransduction pathway; ASSOCIATED WITH Anterior Diaphragmatic Hernia (ortholog); autistic disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); neuromuscular junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plastin-3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955490122,328 - 221,388 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955490125,913 - 221,152 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pls3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955490122,328 - 221,388 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955490125,913 - 221,152 (-)NCBIChiLan1.0ChiLan1.0
PLS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X115,561,174 - 115,650,861 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX115,561,174 - 115,650,861 (+)EnsemblGRCh38hg38GRCh38
GRCh37X114,795,501 - 114,885,181 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X114,701,765 - 114,791,246 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X114,618,488 - 114,707,970NCBI
CeleraX115,230,242 - 115,320,243 (+)NCBICelera
Cytogenetic MapXq23NCBI
HuRefX104,379,340 - 104,468,198 (+)NCBIHuRef
CHM1_1X114,706,001 - 114,796,082 (+)NCBICHM1_1
T2T-CHM13v2.0X113,969,539 - 114,059,207 (+)NCBIT2T-CHM13v2.0
Pls3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X74,829,259 - 74,918,788 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX74,829,260 - 74,918,788 (-)EnsemblGRCm39 Ensembl
GRCm38X75,785,653 - 75,875,182 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX75,785,654 - 75,875,182 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X73,030,993 - 73,120,509 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X72,038,383 - 72,127,258 (-)NCBIMGSCv36mm8
CeleraX67,188,917 - 67,297,722 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX38.3NCBI
Pls3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X116,401,247 - 116,495,898 (+)NCBIGRCr8
mRatBN7.2X111,589,193 - 111,683,908 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX111,589,254 - 111,683,891 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX113,692,615 - 113,779,538 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X117,183,401 - 117,270,327 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X114,734,740 - 114,821,667 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X119,030,311 - 119,124,268 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX119,030,419 - 119,124,250 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X119,173,230 - 119,266,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X29,868,937 - 29,965,118 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X29,923,513 - 29,982,843 (-)NCBI
CeleraX110,881,127 - 110,971,056 (+)NCBICelera
Cytogenetic MapXq34NCBI
PLS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X115,004,895 - 115,098,747 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X115,012,733 - 115,102,356 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X104,656,110 - 104,745,702 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X115,160,032 - 115,250,144 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX115,160,032 - 115,250,144 (+)Ensemblpanpan1.1panPan2
PLS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X88,308,817 - 88,399,682 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX88,308,888 - 88,398,810 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX74,429,089 - 74,519,776 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X90,023,698 - 90,114,659 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX90,022,719 - 90,117,154 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X87,466,392 - 87,557,283 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X89,141,351 - 89,232,259 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X88,976,701 - 89,067,622 (+)NCBIUU_Cfam_GSD_1.0
Pls3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X87,322,781 - 87,411,736 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936499246,042 - 335,440 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936499246,042 - 335,440 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX94,885,118 - 94,971,659 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X94,885,098 - 94,971,664 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X109,452,808 - 109,539,961 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606528,495,210 - 28,582,236 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pls3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624940120,073 - 216,622 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624940120,073 - 216,522 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000002042   ⟹   ENSCLAP00000001997
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955490122,328 - 221,388 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000002043   ⟹   ENSCLAP00000001998
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955490122,328 - 221,388 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000002044   ⟹   ENSCLAP00000001999
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955490122,328 - 179,302 (-)Ensembl
RefSeq Acc Id: XM_005404619   ⟹   XP_005404676
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955490125,913 - 221,152 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504543   ⟹   XP_013359997
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955490125,913 - 179,072 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005404676 (Get FASTA)   NCBI Sequence Viewer  
  XP_013359997 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001997.1
  ENSCLAP00000001998
  ENSCLAP00000001998.1
  ENSCLAP00000001999
  ENSCLAP00000001999.1
RefSeq Acc Id: XP_005404676   ⟸   XM_005404619
- UniProtKB: A0A8C2UJW3 (UniProtKB/TrEMBL),   A0A8C2UPS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013359997   ⟸   XM_013504543
- UniProtKB: A0A8C2UJW3 (UniProtKB/TrEMBL),   A0A8C2UPS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000001998   ⟸   ENSCLAT00000002043
RefSeq Acc Id: ENSCLAP00000001997   ⟸   ENSCLAT00000002042
RefSeq Acc Id: ENSCLAP00000001999   ⟸   ENSCLAT00000002044
Protein Domains
Calponin-homology (CH)   EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001460 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000002042.1 UniProtKB/TrEMBL
  ENSCLAT00000002043 ENTREZGENE
  ENSCLAT00000002043.1 UniProtKB/TrEMBL
  ENSCLAT00000002044 ENTREZGENE
  ENSCLAT00000002044.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro Actinin_actin-bd_CS UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  Fimbrin/Plastin UniProtKB/TrEMBL
NCBI Gene Pls3 ENTREZGENE
PANTHER PTHR19961 UniProtKB/TrEMBL
  PTHR19961:SF32 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PROSITE ACTININ_1 UniProtKB/TrEMBL
  ACTININ_2 UniProtKB/TrEMBL
  EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PS50021 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
  SSF47576 UniProtKB/TrEMBL
UniProt A0A8C2UJW3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UPS8 ENTREZGENE, UniProtKB/TrEMBL