Bag3 (BAG cochaperone 3) - Rat Genome Database

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Gene: Bag3 (BAG cochaperone 3) Chinchilla lanigera
Analyze
Symbol: Bag3
Name: BAG cochaperone 3 (Ensembl:BCL2 associated athanogene 3)
RGD ID: 8931988
Description: ENCODES a protein that exhibits adenyl-nucleotide exchange factor activity (ortholog); protein-containing complex binding (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN cellular response to heat (ortholog); cellular response to mechanical stimulus (ortholog); cellular response to unfolded protein (ortholog); ASSOCIATED WITH arrhythmogenic right ventricular cardiomyopathy (ortholog); asphyxiating thoracic dystrophy 3 (ortholog); atrial fibrillation (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BAG family molecular chaperone regulator 3; BCL2 associated athanogene 3; BCL2-associated athanogene 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955551446,605 - 469,207 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955551446,322 - 468,329 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Bag3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955551446,605 - 469,207 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955551446,322 - 468,329 (+)NCBIChiLan1.0ChiLan1.0
BAG3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810119,651,380 - 119,677,819 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10119,651,380 - 119,677,819 (+)EnsemblGRCh38hg38GRCh38
GRCh3710121,410,892 - 121,437,331 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610121,400,872 - 121,427,321 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410121,400,871 - 121,427,317NCBI
Celera10115,141,910 - 115,168,393 (+)NCBICelera
Cytogenetic Map10q26.11NCBI
HuRef10115,040,288 - 115,066,931 (+)NCBIHuRef
CHM1_110121,695,782 - 121,722,250 (+)NCBICHM1_1
T2T-CHM13v2.010120,548,963 - 120,575,488 (+)NCBIT2T-CHM13v2.0
Bag3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397128,125,307 - 128,148,705 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7128,125,340 - 128,148,705 (+)EnsemblGRCm39 Ensembl
GRCm387128,523,583 - 128,546,981 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7128,523,616 - 128,546,981 (+)EnsemblGRCm38mm10GRCm38
MGSCv377135,667,097 - 135,690,495 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367128,314,764 - 128,355,703 (+)NCBIMGSCv36mm8
Celera7128,367,952 - 128,391,279 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map770.26NCBI
Bag3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,533,460 - 192,557,281 (+)NCBIGRCr8
mRatBN7.21183,103,038 - 183,126,862 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,102,871 - 183,126,858 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,453,498 - 191,477,319 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01198,639,582 - 198,663,403 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01191,309,832 - 191,333,624 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01199,941,258 - 199,965,191 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,941,161 - 199,965,191 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,989,244 - 207,013,177 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,781,147 - 187,804,835 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11187,931,027 - 187,954,715 (+)NCBI
Celera1180,749,355 - 180,773,125 (+)NCBICelera
Cytogenetic Map1q37NCBI
BAG3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28131,509,777 - 131,536,781 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110131,515,147 - 131,541,828 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010116,221,747 - 116,248,692 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110119,654,366 - 119,665,964 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10119,643,963 - 119,665,964 (+)Ensemblpanpan1.1panPan2
BAG3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12829,792,612 - 29,815,466 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2829,792,777 - 29,815,138 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2829,934,645 - 29,957,491 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02830,323,229 - 30,346,844 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2830,322,795 - 30,346,516 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12829,876,932 - 29,899,733 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02829,897,755 - 29,920,635 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02830,092,215 - 30,115,061 (+)NCBIUU_Cfam_GSD_1.0
Bag3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721316,553,837 - 16,575,442 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364868,985,761 - 9,007,502 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364868,985,871 - 9,007,461 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAG3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14129,466,905 - 129,533,987 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114129,510,240 - 129,533,998 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214141,034,569 - 141,058,597 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BAG3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19112,439,954 - 112,465,875 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9112,439,782 - 112,466,086 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604873,714,873 - 73,741,128 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bag3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473727,171,402 - 27,195,004 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473727,171,402 - 27,195,008 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000002147   ⟹   ENSCLAP00000002102
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955551446,605 - 469,207 (+)Ensembl
RefSeq Acc Id: XM_005412164   ⟹   XP_005412221
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955551446,323 - 468,329 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013508589   ⟹   XP_013364043
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955551446,322 - 468,329 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013508590   ⟹   XP_013364044
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955551446,323 - 468,329 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005412221 (Get FASTA)   NCBI Sequence Viewer  
  XP_013364043 (Get FASTA)   NCBI Sequence Viewer  
  XP_013364044 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000002102
  ENSCLAP00000002102.1
Reference Protein Sequences
RefSeq Acc Id: XP_005412221   ⟸   XM_005412164
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UNQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013364043   ⟸   XM_013508589
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013364044   ⟸   XM_013508590
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000002102   ⟸   ENSCLAT00000002147
Protein Domains
BAG   WW


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001524 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000002147 ENTREZGENE
  ENSCLAT00000002147.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.120 UniProtKB/TrEMBL
  2.20.70.10 UniProtKB/TrEMBL
InterPro BAG_chaperone_regulator UniProtKB/TrEMBL
  BAG_dom_sf UniProtKB/TrEMBL
  BAG_domain UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
NCBI Gene Bag3 ENTREZGENE
PANTHER BAG FAMILY MOLECULAR CHAPERONE REGULATOR 3 UniProtKB/TrEMBL
  PTHR12329 UniProtKB/TrEMBL
Pfam BAG UniProtKB/TrEMBL
  PF00397 UniProtKB/TrEMBL
PROSITE BAG UniProtKB/TrEMBL
  WW_DOMAIN_1 UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
SMART BAG UniProtKB/TrEMBL
  SM00456 UniProtKB/TrEMBL
Superfamily-SCOP SSF51045 UniProtKB/TrEMBL
  SSF63491 UniProtKB/TrEMBL
UniProt A0A8C2UNQ8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-26 Bag3  BAG cochaperone 3  Bag3  BCL2 associated athanogene 3  Symbol and/or name change 5135510 APPROVED
2016-08-16 Bag3  BCL2 associated athanogene 3    BCL2-associated athanogene 3  Symbol and/or name change 5135510 APPROVED