Rp2 (RP2 activator of ARL3 GTPase)

Gene: Rp2 (RP2 activator of ARL3 GTPase) Chinchilla lanigera

Analyze

Symbol:

Rp2

Name:

RP2 activator of ARL3 GTPase

RGD ID:

8915981

Description:

ENCODES a protein that exhibits GTPase activator activity (ortholog); magnesium ion binding (ortholog); INVOLVED IN post-chaperonin tubulin folding pathway (ortholog); post-Golgi vesicle-mediated transport (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Eye Abnormalities (ortholog); fundus dystrophy (ortholog); FOUND IN centriole (ortholog); ciliary basal body (ortholog); cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

retinitis pigmentosa 2 (X-linked recessive)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955516	1,160,148 - 1,193,540 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Eye Abnormalities (ISO)

fundus dystrophy (ISO)

genetic disease (ISO)

immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome (ISO)

Kabuki Syndrome 2 (ISO)

Leber congenital amaurosis (ISO)

Neurodevelopmental Disorders (ISO)

polycystic ovary syndrome (ISO)

retinitis pigmentosa (ISO)

retinitis pigmentosa 2 (ISO)

retinitis pigmentosa 3 (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

X-linked epilepsy with variable learning disabilities and behavior disorders (ISO)

X-linked severe congenital neutropenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

post-chaperonin tubulin folding pathway (ISO)

post-Golgi vesicle-mediated transport (ISO)

Cellular Component

centriole (ISO)

ciliary basal body (ISO)

cytoplasm (ISO)

cytoplasmic vesicle (ISO)

Golgi apparatus (ISO)

nuclear body (ISO)

nucleoplasm (ISO)

periciliary membrane compartment (ISO)

plasma membrane (ISO)

Molecular Function

GTPase activator activity (ISO)

magnesium ion binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Rp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955516	1,160,148 - 1,193,540 (-)	NCBI	ChiLan1.0	ChiLan1.0

RP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	46,837,043 - 46,882,358 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	46,837,043 - 46,882,358 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	46,696,478 - 46,741,793 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	46,581,320 - 46,626,737 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	46,452,628 - 46,498,043	NCBI
Celera	X	50,888,193 - 50,933,646 (+)	NCBI		Celera
Cytogenetic Map	X	p11.3	NCBI
HuRef	X	44,407,914 - 44,453,137 (+)	NCBI		HuRef
CHM1_1	X	46,728,434 - 46,773,905 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	46,244,009 - 46,289,363 (+)	NCBI		T2T-CHM13v2.0

Rp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	20,230,778 - 20,271,873 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	20,230,720 - 20,271,892 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	20,364,481 - 20,405,653 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	20,364,481 - 20,405,653 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	19,941,734 - 19,977,475 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	19,521,567 - 19,557,308 (+)	NCBI		MGSCv36	mm8
Celera	X	18,496,211 - 18,531,382 (+)	NCBI		Celera
Cytogenetic Map	X	A1.3	NCBI
cM Map	X	15.83	NCBI

Rp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	4,426,071 - 4,470,200 (-)	NCBI		GRCr8
mRatBN7.2	X	1,872,582 - 1,916,704 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	1,873,306 - 1,916,688 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	1,898,997 - 1,949,550 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	5,374,718 - 5,425,272 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	1,682,649 - 1,726,741 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	2,066,298 - 2,116,661 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	2,064,486 - 2,116,656 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	2,863,068 - 2,908,525 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	X	2,417,995 - 2,461,610 (-)	NCBI		Celera
Cytogenetic Map	X	q11	NCBI

RP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	48,462,495 - 48,510,384 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	48,465,880 - 48,513,762 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	39,274,103 - 39,319,832 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	47,133,639 - 47,178,608 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	47,133,639 - 47,178,608 (+)	Ensembl	panpan1.1		panPan2

RP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	40,472,525 - 40,525,726 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	40,472,596 - 40,524,883 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	14,848,062 - 14,901,255 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	40,606,739 - 40,660,116 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	40,606,744 - 40,659,270 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	40,595,080 - 40,648,018 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	40,582,438 - 40,635,612 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	40,675,509 - 40,728,699 (+)	NCBI		UU_Cfam_GSD_1.0

Rp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	32,815,435 - 32,860,926 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936502	12,656,043 - 12,701,742 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936502	12,656,187 - 12,701,689 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	41,488,626 - 41,534,799 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	41,488,866 - 41,534,810 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	46,325,740 - 46,368,976 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	44,048,319 - 44,090,011 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	44,048,317 - 44,089,988 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666076	9,297,164 - 9,342,282 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624887	3,647,524 - 3,684,618 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624887	3,647,607 - 3,684,383 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005409001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01067413	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCC01018717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005409001 ⟹ XP_005409058

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955516	1,160,148 - 1,193,540 (-)	NCBI

Sequence:

show sequence

TGCTTGCGAGGCTTTCATTGGCTCAATGAGCGCTGAGCAATCATTGGCTGCGGTGGGTAGTCAG
GGCGACTAGGGGAAAAGAAAACGGGGTGCTGGGCCTGGCTGCCTAACAGAGGCTACCGGGTGGC
TGGACTGCTCCGCGAGGGTGATCCGCGGGAGTGGTGTCCCGGAGTGCTGCGGGGCCTGGGCGTC
CAGGAGTCACACTACACTCCAGGAGGTACCTGAGCGAGTGTGCCGCCCGGCAAGACCCGCAGGC
CAGCATCATGGGCTGCTTTTTCTCTAAGGAGCGGAAGACTGAGAAGGAGTCGCGGCGGGAGAAC
GAGGAAGAGCGGCCCAAGAAGTATAGCTGGGACCAGCGTGAAAAGAAATTTTATTTTCCACAGA
TGGTTGGTAAAGGCTTTTTCCTAATTCAGACAAAAGAAGTGTCCATGAAAGCTGAGGATGCAAC
AAGGGTTTTTCAGAACAAAGCACCTGACTACCTTCCCCTTCTAAGTAAAGGTCCTGTGATCGCC
TTGGAGTTCAATGGAGATGGTGTTGTGGAAGAATGTCAGCTTACTATAAATAAGACATTCAATG
GGACCAAGATGTTTGTATCAGAAAACAAGGAGACCGCATCTGAAGATGTAGACAACTTCTACAA
CTTTGTTGATATACAGATGGGAATATGAACTGCAAATGTGGAAAGAAGGATTTGGTATTAAGTC
CTTCCCAACTTTTGTGTGTAAAGTTTGATAATATGCTTTTGTGTATTAGCAGTGATTTTTACTA
ATGCTAAAACTGTTGTGTTATTTTTAAAATAGTTCAATTAAATAGTTTTAATCTACTTAGCAAC
TATTTAGCCCACTTCAATAAGCTTACAGTTTTCTTTCTTTGCTTATAATAACTCTTATTAGAAA
ATAGAAGTGACTACCAGTTCATGATTTTAATCCTAATTAAATGTTCTTTCAAATTTCTAATAAT
TTAAACTTTCCAACTTTCCTCAGTGCTCCATGATATTTGTGTGAGAATACGTTTCATTGCTTAT
TTTATTTTTTTAATTTAGATGGATTTGTTACTATTTGATCAGTTAGAATGAACCTATGCACATT
TTTTTCATGTATACATAGCCAGTTAAATAGTTGCCTCTTAGTTGCATTAAATAGCTAATGAGAT
TTTGTACATTACTTGACATACTACTTTTTAAATTGAATTTTTAAAGAAATAAGTGGTGTGTGAT
TGTAGCCCTAGCTACTCAAGTGGTTCAGGCAGGAGGATCACTTGAGCCCAGGAGTTTGCAGCCA
GCCTGGGCAGCAAAACTAAAAAAAAAAAAAAAACCAACCACAACAACAACAAAAAAAAAAAACA
AAGTGAAGAAATAGGCATTTGATAACTAGCTTTGCAAATAACTCTAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005409058	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005409058 ⟸ XM_005409001
- Sequence:	show sequence MGCFFSKERKTEKESRRENEEERPKKYSWDQREKKFYFPQMVGKGFFLIQTKEVSMKAEDATRV FQNKAPDYLPLLSKGPVIALEFNGDGVVEECQLTINKTFNGTKMFVSENKETASEDVDNFYNFV DIQMGI hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Rp2	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-01-29	Rp2	RP2 activator of ARL3 GTPase		RP2, ARL3 GTPase activating protein	Symbol and/or name change	5135510	APPROVED
2017-02-28	Rp2	RP2, ARL3 GTPase activating protein		retinitis pigmentosa 2 (X-linked recessive)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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