Cabp2 (calcium binding protein 2)

Gene: Cabp2 (calcium binding protein 2) Chinchilla lanigera

Analyze

Symbol:

Cabp2

Name:

calcium binding protein 2

RGD ID:

8876558

Description:

ENCODES a protein that exhibits calcium channel regulator activity (ortholog); INVOLVED IN sensory perception of sound (ortholog); visual perception (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 93 (ortholog); FOUND IN Golgi apparatus (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

calcium-binding protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	17,967,313 - 17,972,468 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	17,967,313 - 17,972,468 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 3 (ISO)

autosomal recessive nonsyndromic deafness (ISO)

autosomal recessive nonsyndromic deafness 93 (ISO)

genetic disease (ISO)

Hearing Loss (ISO)

intellectual disability (ISO)

Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

sensory perception of sound (ISO)

visual perception (ISO)

Cellular Component

Golgi apparatus (ISO)

plasma membrane (ISO)

Molecular Function

calcium channel regulator activity (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium/calcium-mediated signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Cabp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	17,967,313 - 17,972,468 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	17,967,313 - 17,972,468 (+)	NCBI	ChiLan1.0	ChiLan1.0

CABP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	67,518,912 - 67,523,446 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	67,518,912 - 67,524,517 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	67,286,383 - 67,290,917 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	67,042,994 - 67,047,475 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	67,042,993 - 67,047,443	NCBI
Celera	11	64,620,821 - 64,625,302 (-)	NCBI		Celera
Cytogenetic Map	11	q13.2	NCBI
HuRef	11	63,615,628 - 63,620,109 (-)	NCBI		HuRef
CHM1_1	11	67,169,473 - 67,173,954 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	67,513,590 - 67,518,124 (-)	NCBI		T2T-CHM13v2.0

Cabp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	4,131,469 - 4,137,340 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	4,131,578 - 4,137,340 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	4,081,469 - 4,087,340 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	4,081,578 - 4,087,340 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	4,082,488 - 4,087,340 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	4,083,490 - 4,087,340 (+)	NCBI		MGSCv36	mm8
Celera	19	3,953,502 - 3,958,354 (+)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	3.79	NCBI

Cabp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	210,804,111 - 210,809,941 (+)	NCBI		GRCr8
mRatBN7.2	1	201,374,649 - 201,380,469 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	201,375,276 - 201,380,469 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	219,329,186 - 219,335,046 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	219,329,574 - 219,335,043 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	226,198,752 - 226,205,697 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	206,665,715 - 206,670,392 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	198,919,137 - 198,924,997 (+)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

CABP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	68,746,465 - 68,751,006 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	69,789,050 - 69,793,592 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	62,877,978 - 62,882,653 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	66,189,323 - 66,193,993 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

CABP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	49,960,656 - 49,963,889 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	49,959,544 - 49,964,268 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	48,571,195 - 48,574,807 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	50,882,846 - 50,886,458 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	50,881,853 - 50,886,458 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	50,096,161 - 50,099,774 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	49,670,916 - 49,674,529 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	50,464,914 - 50,468,526 (+)	NCBI		UU_Cfam_GSD_1.0

Cabp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	5,803,613 - 5,808,614 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	2,246,177 - 2,250,865 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936599	2,246,139 - 2,250,963 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CABP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	5,014,810 - 5,020,775 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	5,014,888 - 5,020,705 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	3,733,523 - 3,739,224 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CABP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	6,741,202 - 6,744,931 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	104,018,796 - 104,023,454 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cabp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	19,016,945 - 19,022,328 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	19,016,945 - 19,022,328 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005384309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005384310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01022933	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000023146 ⟹ ENSCLAP00000022931

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955422	17,967,313 - 17,972,468 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000023147 ⟹ ENSCLAP00000022932

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955422	17,968,245 - 17,972,468 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000023148 ⟹ ENSCLAP00000022933

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955422	17,968,245 - 17,972,302 (+)	Ensembl

RefSeq Acc Id:

XM_005384309 ⟹ XP_005384366

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955422	17,968,245 - 17,972,468 (+)	NCBI

Sequence:

show sequence

ATGGTTCAGGGGCCTATGGGGAACTGTGCCAAGTGGCCCCGGCGCCGGGGCCCCAAGGACCCCT
GGCAGTGGCCCCGTTCCCCCAGAGGGGGCTCCTGCGGCAATGCCAGTTCCCGCCCCGAAGAGCA
GGGGGCCGTCCAGGGCTACTCGGTGCTTGGCAGCCTGGTGGGGCCGGCCTGTATCTTCCTTCGG
CCCAGCATCGCCGCCACCCAGCTCGATCGGGATCTGCGGCCCGAGGAGATCGAAGAGCTGCAGG
TCGCTTTCCAGGAGTTTGACCGAGACCGGGATGGCTACATCGGCTATCGGGAGCTGGGTGCCTG
CATGCGGACCCTGGGCTACATGCCCACCGAGATGGAGCTCATCGAGATCTCACAGCAAATCAGT
GGCGGGAAGGTGGACTTTGAAGACTTCGTGGAGCTGATGGGCCCCAAGCTGCTGGCGGAAACAG
CAGACATGATCGGCGTCAGGGAGCTTCGGGATGCCTTTCGAGAGTTTGACACCAACGGGGATGG
CTGCATCAGCATAGGGGAGCTTCGGGCTGCCCTCAAGGCCCTGCTGGGGGAGCGCCTCAGCCAG
CGGGAGGTGGACGAGATTCTGCAGGACATCGACCTCAATGGAGATGGCCTGGTTGACTTTGAAG
AATTTGTGCGAATGATGTCTCGCTGAGCCTGTACAGAAGCTGGAGGCAGCAAACAGGACTGGAG
GACCACAGCCTCTTCAGATTGAGTGTGTTCCCAGAAGTCCATCCTGTACAGCTGGGATCCTCCT
CCACCCCTGCCTACCGCCACCCCTTACCCTATCTCTGTTTGTCTGACAATAAAGCATCAGTATG

hide sequence

RefSeq Acc Id:

XM_005384310 ⟹ XP_005384367

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955422	17,967,313 - 17,972,468 (+)	NCBI

Sequence:

show sequence

ATGGCCCTGCCACAGGGCGCAGCAGACAGCAACATCCCCTTGAGGGACCCCAGCCCCTCTGCAG
GGGCTCCAGGTCCCAGCCAGACCCCCACCAGCCCAGCAGCCAGCCGGCGAGCACTTCTCCAGGA
GCTCGAGGCTCAGGTGCAGGCAGCCTATGGGCAGGATCGGGATCTGCGGCCCGAGGAGATCGAA
GAGCTGCAGGTCGCTTTCCAGGAGTTTGACCGAGACCGGGATGGCTACATCGGCTATCGGGAGC
TGGGTGCCTGCATGCGGACCCTGGGCTACATGCCCACCGAGATGGAGCTCATCGAGATCTCACA
GCAAATCAGTGGCGGGAAGGTGGACTTTGAAGACTTCGTGGAGCTGATGGGCCCCAAGCTGCTG
GCGGAAACAGCAGACATGATCGGCGTCAGGGAGCTTCGGGATGCCTTTCGAGAGTTTGACACCA
ACGGGGATGGCTGCATCAGCATAGGGGAGCTTCGGGCTGCCCTCAAGGCCCTGCTGGGGGAGCG
CCTCAGCCAGCGGGAGGTGGACGAGATTCTGCAGGACATCGACCTCAATGGAGATGGCCTGGTT
GACTTTGAAGAATTTGTGCGAATGATGTCTCGCTGAGCCTGTACAGAAGCTGGAGGCAGCAAAC
AGGACTGGAGGACCACAGCCTCTTCAGATTGAGTGTGTTCCCAGAAGTCCATCCTGTACAGCTG
GGATCCTCCTCCACCCCTGCCTACCGCCACCCCTTACCCTATCTCTGTTTGTCTGACAATAAAG
CATCAGTATG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005384366	(Get FASTA)	NCBI Sequence Viewer
	XP_005384367	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000022931
	ENSCLAP00000022931.1
	ENSCLAP00000022932
	ENSCLAP00000022932.1
	ENSCLAP00000022933.1

RefSeq Acc Id:	XP_005384367 ⟸ XM_005384310
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2W460 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALPQGAADSNIPLRDPSPSAGAPGPSQTPTSPAASRRALLQELEAQVQAAYGQDRDLRPEEIE ELQVAFQEFDRDRDGYIGYRELGACMRTLGYMPTEMELIEISQQISGGKVDFEDFVELMGPKLL AETADMIGVRELRDAFREFDTNGDGCISIGELRAALKALLGERLSQREVDEILQDIDLNGDGLV DFEEFVRMMSR hide sequence

RefSeq Acc Id:	XP_005384366 ⟸ XM_005384309
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2W6H8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVQGPMGNCAKWPRRRGPKDPWQWPRSPRGGSCGNASSRPEEQGAVQGYSVLGSLVGPACIFLR PSIAATQLDRDLRPEEIEELQVAFQEFDRDRDGYIGYRELGACMRTLGYMPTEMELIEISQQIS GGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGCISIGELRAALKALLGERLSQ REVDEILQDIDLNGDGLVDFEEFVRMMSR hide sequence

RefSeq Acc Id:

ENSCLAP00000022933 ⟸ ENSCLAT00000023148

RefSeq Acc Id:

ENSCLAP00000022931 ⟸ ENSCLAT00000023146

RefSeq Acc Id:

ENSCLAP00000022932 ⟸ ENSCLAT00000023147

Protein Domains

EF-hand

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000015734	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000023146	ENTREZGENE
	ENSCLAT00000023146.1	UniProtKB/TrEMBL
	ENSCLAT00000023147	ENTREZGENE
	ENSCLAT00000023147.1	UniProtKB/TrEMBL
	ENSCLAT00000023148.1	UniProtKB/TrEMBL
Gene3D-CATH	EF-hand	UniProtKB/TrEMBL
InterPro	CaBP1/2/4/5	UniProtKB/TrEMBL
	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
NCBI Gene	Cabp2	ENTREZGENE
PANTHER	PTHR45917	UniProtKB/TrEMBL
	PTHR45917:SF2	UniProtKB/TrEMBL
Pfam	EF-hand_7	UniProtKB/TrEMBL
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
SMART	EFh	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	A0A8C2W2B3_CHILA	UniProtKB/TrEMBL
	A0A8C2W460	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2W6H8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

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