Dusp26 (dual specificity phosphatase 26)

Gene: Dusp26 (dual specificity phosphatase 26) Chinchilla lanigera

Analyze

Symbol:

Dusp26

Name:

dual specificity phosphatase 26

RGD ID:

8863922

Description:

ENCODES a protein that exhibits p53 binding (ortholog); phosphoprotein phosphatase activity (ortholog); protein tyrosine/serine/threonine phosphatase activity (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of cell adhesion (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog); nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

dual specificity phosphatase 26 (putative); dual specificity protein phosphatase 26

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	9,712,954 - 9,718,959 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	9,712,943 - 9,718,959 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of ERK1 and ERK2 cascade (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

positive regulation of cell adhesion (ISO)

Cellular Component

cytoplasm (ISO)

Golgi apparatus (ISO)

nucleoplasm (ISO)

nucleus (ISO)

Molecular Function

p53 binding (ISO)

phosphoprotein phosphatase activity (ISO)

protein binding (ISO)

protein tyrosine/serine/threonine phosphatase activity (ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Dusp26
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	9,712,954 - 9,718,959 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	9,712,943 - 9,718,959 (-)	NCBI	ChiLan1.0	ChiLan1.0

DUSP26
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	33,591,330 - 33,600,023 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	33,591,330 - 33,600,023 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	33,448,848 - 33,457,541 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	33,568,393 - 33,576,981 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	32,398,523 - 32,407,113 (-)	NCBI		Celera
Cytogenetic Map	8	p12	NCBI
HuRef	8	31,980,747 - 31,988,923 (-)	NCBI		HuRef
CHM1_1	8	33,650,334 - 33,658,924 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	33,862,584 - 33,871,277 (-)	NCBI		T2T-CHM13v2.0

Dusp26
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	31,579,555 - 31,587,074 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	31,579,499 - 31,587,075 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	31,089,527 - 31,097,046 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	31,089,471 - 31,097,047 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	32,200,134 - 32,207,519 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	32,555,597 - 32,562,982 (+)	NCBI		MGSCv36	mm8
Celera	8	32,614,701 - 32,622,121 (+)	NCBI		Celera
Cytogenetic Map	8	A3	NCBI
cM Map	8	17.93	NCBI

Dusp26
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	67,744,830 - 67,752,673 (-)	NCBI		GRCr8
mRatBN7.2	16	61,041,784 - 61,049,319 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	61,041,792 - 61,049,051 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	66,357,195 - 66,364,502 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	69,771,709 - 69,779,012 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	64,998,081 - 65,005,413 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	64,798,782 - 64,806,459 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	64,798,778 - 64,806,050 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	64,455,731 - 64,463,284 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	64,952,300 - 64,959,604 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	64,952,379 - 64,959,679 (-)	NCBI
Celera	16	59,046,361 - 59,053,665 (-)	NCBI		Celera
Cytogenetic Map	16	q12.3	NCBI

DUSP26
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	52,166,122 - 52,174,877 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	27,881,863 - 27,890,613 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	32,906,182 - 32,915,015 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	30,091,084 - 30,100,699 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	30,091,092 - 30,100,699 (-)	Ensembl	panpan1.1		panPan2

DUSP26
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	31,115,317 - 31,122,767 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	31,115,475 - 31,132,033 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	31,638,685 - 31,647,937 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	33,140,928 - 33,146,814 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	33,141,000 - 33,147,846 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	31,237,257 - 31,246,487 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	31,816,290 - 31,822,141 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	31,854,968 - 31,864,230 (+)	NCBI		UU_Cfam_GSD_1.0

Dusp26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	54,103,079 - 54,109,849 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936766	363,029 - 370,281 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936766	363,172 - 370,234 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DUSP26
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa10.2	15	59,480,305 - 59,486,816 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DUSP26
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	31,667,984 - 31,679,040 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	31,666,691 - 31,679,058 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	10,369,786 - 10,378,220 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dusp26
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624780	10,368,975 - 10,375,215 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624780	10,368,988 - 10,376,731 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005398407	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01049796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCB01005948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01009430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000004691 ⟹ ENSCLAP00000004605

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955463	9,712,954 - 9,718,959 (-)	Ensembl

RefSeq Acc Id:

XM_005398407 ⟹ XP_005398464

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955463	9,712,943 - 9,718,959 (-)	NCBI

Sequence:

show sequence

CACGTTTGTGTGTATGTGCGCGTGCCTGTGTGCGCGCGGGGGCGGCGCCGCCCGGAGACCCGGA
GGCCGCGCGAGCGGGGCTCCACAATTGGCCGCCGGCGGGCGCGGGCTGGGTCTGGGCCCGCGAG
CGGTGGGGCGCCGGCGGCCGGACCCCGCTCCCTGCGGCCCGAGCCCTGCGTGTGTCCCGCGAGC
GCGCGCGCCGCGGCGAACCTGGCTTCGAGTGGGCGTCGCGGCTGGAAATAGCTGAAGCCGGCGG
CGGCGGGGAGCATGGCCGCCCGCGGCCTCGGGGACGCCTGAGCCGCCCAGCAGCTCACCTGGTG
CCCAACCCCGTCGTCCCCGCAGCCACCCGGCAGCTGCCCCGGCTCCTCCTGCTCTACAATGTGC
CCCGGGAACTGGCTGTGGGCCTCCATGACGTTCATGGCCCGCTTCTCCAGGAGTAGCTCAAGGT
CCCCTGTTCGCACCAGAGGGAGCCTGGAGGACATGCCACCCGTGCAGCATCCCTTCCTCAACGT
CTTTGAGCTGGAGCGGCTCCTGTACACAGGCAAGACAGCCTGTAACCACGCTGACGAGGTCTGG
CCAGGCCTCTACCTTGGAGACCAGGACATGGCCAACAACCGTCGGGAGCTGCGACGCCTGGGCA
TCACCCATGTCCTCAACGCCTCGCACAGCAGGTGGCGGGGCATACCCGAGGCCTATGAGGGGCT
GGGGATCCGCTACCTGGGTGTGGAGGCCCACGACTCCCCAGCCTTTGACATGAGCATCCACTTC
CAGACAGCTGCGGACTTCATCCACCGGGCGCTGAGCCAGCCAGGAGGCAAGATCCTGGTGCACT
GCGCCGTGGGAGTGAGCCGATCCGCCACGCTGGTGCTCGCCTACCTCATGCTGTACCACCGCTT
CACCCTCGTGGAGGCCATCAAGAAAGTCAAGGACCACCGAGGCATCATCCCCAACCGGGGCTTC
TTGAGGCAGCTCCTGGCCCTGGACCGCAGGCTGCGGCAGAGTCTGGAGGCCTGAGCGGAGGGGC
CAGGAGGTCAGGCCAGGCCCAGGTGGATCCCTGGCTTCACCTGGAGACAAGAGGCCCAGCCGGC
GGGGAGCAGAAAGCCCAAGGAGCCCGTCTTCTCCTGGGGCCAAGGCCCAGGCCACTGCTGCCCT
CTGTGAGAGCGGTGAGAGGTGAAGGTGGGTGGTGTGGGGGACAGGTGCCCAGGGGTGTGACCAG
GAAAGGAGGAGCCAGGCTGCAGGTAGAAGGATGTCCCCAGGTACACGCGGTCCCTTCCCCTCTT
TGTGTGCAGGTGTTCTCCTCTTTCCCTTACAAAAACAAAAGGGCCGTCTCTGCCCTGTGCCCAT
GCAAGGAGTCCCAGATGCAGCCGCACAAATGTGTGGGGTTGCGCGCAGACCATAGCATAGAGAC
AGATGACCTGGGTGATGTGAAAAGCTGTAAAGCCAGAGGGAGATTCCCCGCAGACTTGCTACAG
CAAGCATGGCACGAGCAGGTGTGTGCCGGCTGGCATGGCGCCCATGGGTGCTGCTGGTGGCCAA
GAGAATCGCAGAGGTGCATGACTGGCAGGCGTTGTTGGTACTGGATCCAGGTATCTGGATGAAA
AATAAAGACACTGGAAAAGAAGAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005398464	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000004605
	ENSCLAP00000004605.1

RefSeq Acc Id:

XP_005398464 ⟸ XM_005398407

- UniProtKB:

A0A8C2USG0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MCPGNWLWASMTFMARFSRSSSRSPVRTRGSLEDMPPVQHPFLNVFELERLLYTGKTACNHADE
VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGIPEAYEGLGIRYLGVEAHDSPAFDMSI
HFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHRFTLVEAIKKVKDHRGIIPNR
GFLRQLLALDRRLRQSLEA

hide sequence

RefSeq Acc Id:

ENSCLAP00000004605 ⟸ ENSCLAT00000004691

Protein Domains

Tyrosine specific protein phosphatases Tyrosine-protein phosphatase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000003277	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000004691	ENTREZGENE
	ENSCLAT00000004691.1	UniProtKB/TrEMBL
Gene3D-CATH	3.90.190.10	UniProtKB/TrEMBL
InterPro	Atypical_DUSP_subfamA	UniProtKB/TrEMBL
	Dual-sp_phosphatase_cat-dom	UniProtKB/TrEMBL
	Prot-tyrosine_phosphatase-like	UniProtKB/TrEMBL
	Tyr_Pase_AS	UniProtKB/TrEMBL
	Tyr_Pase_dom	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_DUAL_dom	UniProtKB/TrEMBL
NCBI Gene	Dusp26	ENTREZGENE
PANTHER	DUAL SPECIFICITY PROTEIN PHOSPHATASE 26	UniProtKB/TrEMBL
	PTHR45682	UniProtKB/TrEMBL
Pfam	DSPc	UniProtKB/TrEMBL
PRINTS	ADSPHPHTASE	UniProtKB/TrEMBL
	ADSPHPHTASEA	UniProtKB/TrEMBL
PROSITE	TYR_PHOSPHATASE_1	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_2	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_DUAL	UniProtKB/TrEMBL
SMART	DSPc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52799	UniProtKB/TrEMBL
UniProt	A0A8C2USG0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-12-13	Dusp26	dual specificity phosphatase 26		dual specificity phosphatase 26 (putative)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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