Ier2 (immediate early response 2)

Gene: Ier2 (immediate early response 2) Chinchilla lanigera

Analyze

Symbol:

Ier2

Name:

immediate early response 2

RGD ID:

8847881

Description:

INVOLVED IN cell motility (ortholog); neuron differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH alpha-mannosidosis (ortholog); Charcot-Marie-Tooth disease dominant intermediate B (ortholog); childhood acute myeloid leukemia (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	32,159,935 - 32,160,624 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	32,159,762 - 32,161,530 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alpha-mannosidosis (ISO)

Charcot-Marie-Tooth disease dominant intermediate B (ISO)

childhood acute myeloid leukemia (ISO)

colorectal adenocarcinoma (ISO)

colorectal cancer (ISO)

COVID-19 (ISO)

episodic ataxia type 2 (ISO)

genetic disease (ISO)

glutaric acidemia I (ISO)

hepatocellular carcinoma (ISO)

Lung Neoplasms (ISO)

Lymphatic Metastasis (ISO)

Marshall-Smith syndrome (ISO)

melanoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell motility (ISO)

neuron differentiation (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

response to fibroblast growth factor (ISO)

Cellular Component

cytoplasm (ISO)

nucleoplasm (ISO)

nucleus (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data

Ier2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	32,159,935 - 32,160,624 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	32,159,762 - 32,161,530 (+)	NCBI	ChiLan1.0	ChiLan1.0

IER2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	13,150,411 - 13,154,911 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	13,150,411 - 13,154,911 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	13,261,225 - 13,265,725 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	13,122,282 - 13,126,722 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	13,122,281 - 13,126,716	NCBI
Celera	19	13,151,680 - 13,156,120 (+)	NCBI		Celera
Cytogenetic Map	19	p13.13	NCBI
HuRef	19	12,833,675 - 12,838,116 (+)	NCBI		HuRef
CHM1_1	19	13,262,236 - 13,266,676 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	13,275,624 - 13,280,125 (+)	NCBI		T2T-CHM13v2.0

Ier2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	85,387,960 - 85,389,481 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	85,387,960 - 85,389,483 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	84,661,331 - 84,662,852 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	84,661,331 - 84,662,854 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	87,185,230 - 87,186,751 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	87,549,656 - 87,552,953 (-)	NCBI		MGSCv36	mm8
Celera	8	88,961,236 - 88,962,757 (-)	NCBI		Celera
Cytogenetic Map	8	C3	NCBI
cM Map	8	41.02	NCBI

Ier2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	40,399,373 - 40,400,897 (+)	NCBI		GRCr8
mRatBN7.2	19	23,494,551 - 23,496,075 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	23,494,184 - 23,499,211 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	30,317,473 - 30,318,997 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	30,971,850 - 30,973,374 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	33,194,540 - 33,196,064 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	25,774,146 - 25,775,670 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	25,774,143 - 25,775,659 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	36,750,509 - 36,752,033 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	25,159,276 - 25,160,800 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	25,164,101 - 25,165,622 (+)	NCBI
Celera	19	23,048,157 - 23,049,681 (+)	NCBI		Celera
Cytogenetic Map	19	q11	NCBI

IER2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	18,081,380 - 18,085,241 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	17,082,479 - 17,085,886 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	12,714,804 - 12,718,213 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	13,449,491 - 13,452,925 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	13,452,239 - 13,452,910 (+)	Ensembl	panpan1.1		panPan2

IER2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	49,071,243 - 49,074,184 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	49,072,234 - 49,072,902 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	48,944,380 - 48,946,236 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	49,588,863 - 49,590,720 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	49,588,864 - 49,590,663 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	48,800,441 - 48,802,297 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	49,226,806 - 49,228,663 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	49,469,195 - 49,471,051 (-)	NCBI		UU_Cfam_GSD_1.0

Ier2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	208,174,816 - 208,177,770 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936659	2,178,312 - 2,178,983 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936659	2,176,962 - 2,179,900 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IER2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	65,909,651 - 65,912,445 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	65,909,638 - 65,912,491 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	66,210,147 - 66,211,956 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IER2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	11,834,998 - 11,838,421 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	11,836,706 - 11,837,377 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	7,945,206 - 7,948,333 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ier2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624901	684,966 - 685,652 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624901	684,313 - 686,488 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005381057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01016712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDK01079819	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000022529 ⟹ ENSCLAP00000022324

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955415	32,159,935 - 32,160,624 (+)	Ensembl

RefSeq Acc Id:

XM_005381057 ⟹ XP_005381114

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955415	32,159,762 - 32,161,530 (+)	NCBI

Sequence:

show sequence

TGGGCGGGGCGCCGCTGATGTCATCTTGGGTACAAAAGGGCTCGAGTGGCCGGCTCCTGGGCAG
AGCTTACGACCTGACGGCGTTGAGAGAATTGGCGCGTCTTCCGCAGAGCACCAACCGCTATCTG
TTCCGCGCTGCTCAGAGTCCCTGTATCCCTTACCGTCGAGTTGCCATGGAGGTGCAGAAGGAGG
CACAGCGCATCATGACACTATCGGTGTGGAAAATGTATCACTCGCGTATGCAGCGCGGAGGCCT
GCGCCTGCACCGAAGTCTGCAGCTGTCGCTGATCATGCGCAGCGCCCGGGAGCTCTACCTCTCG
GCCAAAGTGGAGGCCCTCGATCTCGAGGCGCCCTCGCCGCCCGCCCGCTGCCCGGACCCGCGCC
TGCACCCGCCGCGGGAAGTGGAAGTGCCCGCCGCGTGTGTGCCCCCCGACGGGGAGCAGCCGTT
GCCGGAGCCTATGGACACGCAGGAAGAGGAGGAGGCGCCCCCCAGAGCCGCGGAGACGGAGACT
CTGGTCCGTTGCTCCCCGCGCCCCGCCAGGGTCTGCCGCAAGCGACGCAGTAGCAGCCTTAGCG
ACGGCGTGGACGCCGGCCTGGTCCCCAGCAAGAAGGCCCGCTTGGAGGAGCAGGAGGAGGCAAA
GGACTCGTCCTCTGAGGTTCCCGATTGCCTGCCGCCCCCACCCGCTCAGGCGGAAGGCGCCTTC
CCCAACCTGGCGCGCGTCCTGCAGCGAAGCTTCTCCGGGCTCCTGAGCCGCGGCCCTGCCGCTT
CCCCGACGGCGCCCCCCGCGCGTGACGCCAAGCCGGCCTGTCGCCCGGCGGACCCGATGCTGAG
CGTGCTTGTGCGCGCCGTGGTGGCCTTCTGAGGACCGAGCCCGCTGCCGGAGCCAGAGAGCGCG
CCGAGCCGTCGACCCGAGTGCGCAACACAAGGCGTTACGCCCTCCCCGAGGCATGTGAGCCAGC
GGGAGCGGAGGAGGAGCGAGGCGGCCGCCCGGGCTGAGGGAGCCGCAGAGGGACAGTGCCCGGG
GATCGTCGCCGTCCACGCTGCGGCGGCCCAGGAGCCGGGGGGCGCGGGCGCCTTCCGCGAGCCC
CGCGGCGCCCAGAGGTGCTGATTTACGGACTGGGACCTGGGCCTTGACCTCTCCCACGCTGGGA
GAGAGGTTCGGTCTATCAATCTCAGGGTCGGACTTCATTTTTTTTTTTTTTTTTTTTTTAAATC
AAGCGCTGGGCCACGTTTTCCAAGACTTGCCAGTGTGTGCCCTTCCAGCTTCAGAATTCCAGGC
GCTCCCCTGCTCCTCTGGTGACACACTTGTGCAAGCGGTCACCGTTGCGTCATGGGGCAGGGGT
GGGGAGCTTCCTGTCGCCTAGCGTGGGTGTGGGGCCCGGGAGGCGGCTCCGGGGCGTAGACCGC
CCTGGGGAGTGGGAGGAGTGCGGCCTGAGTCACTGCGCCCCGCCTCACCACCGCCGCGAGAGCC
CTGCGAGTTTCTGATTCATTGTTTTTTTGTTTTTTAATTTCCTCATTTGTTTGTGCTAAGAGGT
GGCGCGATGTTCCCAGCCCGGAGCGTGACCTCCCTTGGACACACGGACACGCAACCCAGATGGA
CCTTGGAGGGGTGGGAAGGGGGGGCGCCCTTGGCGCCCGGACTGAGCTGAGACGGAAGGATGCC
CGCCTGGGCGGTGGAGCCCTGTTTACCTTTCCCGCAGTGGGTGCCGTCTACCTGGCGTCTCTTT
GGAAATGTCAGCCAGGACAATAAAGACCATTGCAGTGGAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005381114	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000022324.1

RefSeq Acc Id:

XP_005381114 ⟸ XM_005381057

- Sequence:

show sequence

MSSWVQKGSSGRLLGRAYDLTALRELARLPQSTNRYLFRAAQSPCIPYRRVAMEVQKEAQRIMT
LSVWKMYHSRMQRGGLRLHRSLQLSLIMRSARELYLSAKVEALDLEAPSPPARCPDPRLHPPRE
VEVPAACVPPDGEQPLPEPMDTQEEEEAPPRAAETETLVRCSPRPARVCRKRRSSSLSDGVDAG
LVPSKKARLEEQEEAKDSSSEVPDCLPPPPAQAEGAFPNLARVLQRSFSGLLSRGPAASPTAPP
ARDAKPACRPADPMLSVLVRAVVAF

hide sequence

RefSeq Acc Id:

ENSCLAP00000022324 ⟸ ENSCLAT00000022529

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000015309	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000022529.1	UniProtKB/TrEMBL
InterPro	IER	UniProtKB/TrEMBL
NCBI Gene	Ier2	ENTREZGENE
PANTHER	IMMEDIATE EARLY RESPONSE GENE 2 PROTEIN	UniProtKB/TrEMBL
	PTHR15895	UniProtKB/TrEMBL
Pfam	IER	UniProtKB/TrEMBL
UniProt	A0A8C2VYH5_CHILA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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