Bcl2a1 (BCL2 related protein A1) - Rat Genome Database

Name: Bcl2a1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Bcl2a1 (BCL2 related protein A1) Chinchilla lanigera

Analyze

Symbol:

Bcl2a1

Name:

BCL2 related protein A1

RGD ID:

8846566

Description:

ENCODES a protein that exhibits BH domain binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cerebral cortex development (ortholog); PARTICIPATES IN intrinsic apoptotic pathway; ASSOCIATED WITH allergic disease (ortholog); Bloom syndrome (ortholog); Breast Neoplasms (ortholog); FOUND IN cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

bcl-2-related protein A1; BCL2-related protein A1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955533	773,912 - 785,037 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955533	773,912 - 785,040 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

allergic disease (ISO)

Bloom syndrome (ISO)

Breast Neoplasms (ISO)

colorectal cancer (ISO)

COVID-19 (ISO)

Esophageal Neoplasms (ISO)

rheumatoid arthritis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cerebral cortex development (ISO)

Cellular Component

cytoplasm (ISO)

Molecular Function

BH domain binding (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

intrinsic apoptotic pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Bcl2a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955533	773,912 - 785,037 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955533	773,912 - 785,040 (-)	NCBI	ChiLan1.0	ChiLan1.0

BCL2A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	79,960,892 - 79,971,196 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	79,960,892 - 79,971,196 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	80,253,234 - 80,263,538 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	78,040,290 - 78,050,698 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	78,040,289 - 78,050,698	NCBI
Celera	15	57,189,526 - 57,199,937 (-)	NCBI		Celera
Cytogenetic Map	15	q25.1	NCBI
HuRef	15	57,011,277 - 57,021,688 (-)	NCBI		HuRef
CHM1_1	15	80,370,121 - 80,380,532 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	77,823,803 - 77,834,097 (-)	NCBI		T2T-CHM13v2.0

Bcl2a1b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	89,081,326 - 89,089,891 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	89,081,262 - 89,089,880 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	89,199,273 - 89,207,838 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	89,199,209 - 89,207,827 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	89,094,111 - 89,102,676 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	88,997,122 - 89,005,719 (+)	NCBI		MGSCv36	mm8
Celera	9	87,568,132 - 87,573,632 (-)	NCBI		Celera
Cytogenetic Map	9	E3.1	NCBI
cM Map	9	47.24	NCBI

Bcl2a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	98,596,806 - 98,604,890 (+)	NCBI		GRCr8
mRatBN7.2	8	89,716,914 - 89,724,998 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	89,716,914 - 89,724,998 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	95,382,133 - 95,390,252 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	93,581,342 - 93,589,461 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	91,445,125 - 91,453,238 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	96,551,424 - 96,559,527 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	96,551,245 - 96,559,483 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	96,059,040 - 96,067,299 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	94,045,109 - 94,053,777 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	94,064,563 - 94,073,232 (+)	NCBI
Celera	8	89,278,398 - 89,286,468 (+)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

BCL2A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	69,210,990 - 69,220,256 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	73,375,852 - 73,385,125 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	58,925,853 - 58,935,122 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	77,884,030 - 77,893,167 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	77,882,940 - 77,893,628 (-)	Ensembl	panpan1.1		panPan2

BCL2A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	57,451,512 - 57,463,692 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	57,424,555 - 57,463,692 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	60,109,775 - 60,121,887 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	57,884,668 - 57,896,576 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	3	57,383,698 - 57,395,826 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	57,590,934 - 57,602,831 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	57,937,969 - 57,949,867 (+)	NCBI		UU_Cfam_GSD_1.0

Bcl2a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	120,133,708 - 120,163,718 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	37,981,772 - 37,993,116 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	37,981,851 - 37,993,097 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BCL2A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	48,887,094 - 48,897,870 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	48,887,227 - 48,897,667 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	54,395,262 - 54,419,816 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BCL2A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	3,451,773 - 3,461,215 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	3,451,873 - 3,461,180 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	138,408,361 - 138,418,275 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bcl2a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624941	907,119 - 933,356 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624941	907,382 - 932,751 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005410388	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001232042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01070329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01389835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000002706 ⟹ ENSCLAP00000002651

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955533	773,912 - 785,037 (-)	Ensembl

RefSeq Acc Id:

XM_005410388 ⟹ XP_005410445

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955533	773,912 - 785,037 (-)	NCBI

Sequence:

show sequence

TACGTAACAACGTGGGTGGAAGGATCCTGAACCATGATGCAAACAGAAAATCCACCGGTCAGGC
TATCACCATGGGTCACATCCTGCTCAGCTCTACTGCCGGCAGCCTCAGTCTGCCCGCACAGGCC
CCGGGCAAGCCGGCTCCAGGCTGCCCTCCCCAGCCCAAGATGATTGACCAGGAGTTCAGGTACA
CGCAAACTCTGGCCCAGGAGTACCTGCTGCACGTCCTGCAGGTGCCGCAGTGCGGGGCCAGCCC
CAGCAGGACGTCCAGAGTGCTACAGGGTGTGGCTTTCTCAGTGCAGAAAGAAGTGGAGGAGAGC
CTGAAGCCGTGGTTGGACAGATGCGATGTGGCGTCCGTCAACGCTGCCAGGGCGATATTCACCC
AGGTGATGGAGAAGGAGTTCGAGGACGGCATCATTAACTGGGGGCGGATTGTGACCATATTTGC
TTTTGGGGGAGTCATCCTCAAGAAACTTCCGCGAGAGCCGCTGGCCCCAGATGTGGACACTTAC
AGGGAGATTTCTCACTTTGTGGCTGAGTTCGTAGTGAACCACACGGGAGACTGGATCCGGCAGA
ACGGAGGCTGGGAAAACGGCTTTGTGAGGAAGTTTGAGCCCAAATTTGGCTGGCTGACCTTCGT
GGGAGTTCTGGGACAGATCTGTGAGATGCTGTCCCTCCTGAAGCAATTCTACTGATCGAAAGGA
CTCTGACTGTTGAGAGAGCTACTGCCACACAGGCCCTTCCTCCTCAAAGCCCTCACGATGTTTC
CCGACTGTCCAAAGCTACGGACTTCTGTCCCTCTTTTAATAAATTAATTGTCTCTGTA

hide sequence

RefSeq Acc Id:

XR_001232042

Type:

NON-CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955533	774,058 - 785,040 (-)	NCBI

Sequence:

show sequence

GCCTACGTAACAACGTGGGTGGAAGGATCCTGAACCATGATGCAAACAGAAAATCCACCGGTCA
GGCTATCACCATGGGTCACATCCTGCTCAGCTCTACTGCCGGCAGCCTCAGTCTGCCCGCACAG
GCCCCGGGCAAGCCGGCTCCAGGCTGCCCTCCCCAGCCCAAGATGATTGACCAGGAGTTCAGGT
ACACGCAAACTCTGGCCCAGGAGTACCTGCTGCACGTCCTGCAGGTGCCGCAGTGCGGGGCCAG
CCCCAGCAGGACGTCCAGAGTGCTACAGGGTGTGGCTTTCTCAGTGCAGAAAGAAGTGGAGGAG
AGCCTGAAGCCGTGGTTGGACAGATGCGATGTGGCGTCCGTCAACGCTGCCAGGGCGATATTCA
CCCAGGTGATGGAGAAGGAGTTCGAGGACGGCATCATTAACTGGGGGCGGATTGTGACCATATT
TGCTTTTGGGGGAGTCATCCTCAAGAAACTTCCGCGAGAGCCGCTGGCCCCAGATGTGGACACT
TACAGGGAGATTTCTCACTTTGTGGCTGAGTTCGTAGTGAACCACACGGGAGACTGGATCCGGC
AGAACGGAGGCTGGGCCGTGGACAAGGAAAGCCACGCGTGAAGCTCCGGCGTGCCTCTGTGGGA
CCCTGCGTGTGTGCGGTCTGGCTCTGGAGGAAAACGGCTTTGTGAGGAAGTTTGAGCCCAAATT
TGGCTGGCTGACCTTCGTGGGAGTTCTGGGACAGATCTGTGAGATGCTGTCCCTCCTG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005410445	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000002651
	ENSCLAP00000002651.1

RefSeq Acc Id:

XP_005410445 ⟸ XM_005410388

- UniProtKB:

A0A8C2UN30 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGHILLSSTAGSLSLPAQAPGKPAPGCPPQPKMIDQEFRYTQTLAQEYLLHVLQVPQCGASPSR
TSRVLQGVAFSVQKEVEESLKPWLDRCDVASVNAARAIFTQVMEKEFEDGIINWGRIVTIFAFG
GVILKKLPREPLAPDVDTYREISHFVAEFVVNHTGDWIRQNGGWENGFVRKFEPKFGWLTFVGV
LGQICEMLSLLKQFY

hide sequence

RefSeq Acc Id:

ENSCLAP00000002651 ⟸ ENSCLAT00000002706

Protein Domains

Bcl-2 Bcl-2 homology region 1-3

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000001913	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000002706	ENTREZGENE
	ENSCLAT00000002706.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.437.10	UniProtKB/TrEMBL
InterPro	Bcl-2-like_sf	UniProtKB/TrEMBL
	Bcl-2_BH1-3	UniProtKB/TrEMBL
	Bcl-2_fam	UniProtKB/TrEMBL
	Bcl2-like	UniProtKB/TrEMBL
	Bcl2_BH1_motif_CS	UniProtKB/TrEMBL
	Bcl2_BH2_motif_CS	UniProtKB/TrEMBL
	Bcl2A1	UniProtKB/TrEMBL
NCBI Gene	Bcl2a1	ENTREZGENE
PANTHER	PTHR11256	UniProtKB/TrEMBL
	PTHR11256:SF10	UniProtKB/TrEMBL
Pfam	Bcl-2	UniProtKB/TrEMBL
PRINTS	BCL2FAMILY	UniProtKB/TrEMBL
	BCL2RLATEDA1	UniProtKB/TrEMBL
PROSITE	BCL2_FAMILY	UniProtKB/TrEMBL
	BH1	UniProtKB/TrEMBL
	BH2	UniProtKB/TrEMBL
SMART	BCL	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56854	UniProtKB/TrEMBL
UniProt	A0A8C2UN30	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Bcl2a1	BCL2 related protein A1		BCL2-related protein A1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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