Efcab7 (EF-hand calcium binding domain 7) - Rat Genome Database

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Gene: Efcab7 (EF-hand calcium binding domain 7) Chinchilla lanigera
Analyze
Symbol: Efcab7
Name: EF-hand calcium binding domain 7
RGD ID: 8826422
Description: INVOLVED IN positive regulation of protein import into nucleus (ortholog); positive regulation of protein localization to ciliary membrane (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Craniosynostosis Syndrome, Autosomal Recessive (ortholog); intellectual disability (ortholog); Postaxial Polydactyly (ortholog); FOUND IN ciliary membrane (ortholog); cytoplasmic side of plasma membrane (ortholog); plasma membrane protein complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EF-hand calcium-binding domain-containing protein 7
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542326,474,568 - 26,509,196 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542326,473,310 - 26,510,704 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Efcab7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542326,474,568 - 26,509,196 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542326,473,310 - 26,510,704 (-)NCBIChiLan1.0ChiLan1.0
EFCAB7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,523,525 - 63,585,370 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl163,523,372 - 63,572,693 (+)EnsemblGRCh38hg38GRCh38
GRCh37163,989,196 - 64,038,364 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,761,856 - 63,810,952 (+)NCBINCBI36Build 36hg18NCBI36
Celera162,278,938 - 62,328,273 (+)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef162,097,101 - 62,146,337 (+)NCBIHuRef
CHM1_1164,104,820 - 64,154,155 (+)NCBICHM1_1
T2T-CHM13v2.0163,399,112 - 63,465,319 (+)NCBIT2T-CHM13v2.0
Efcab7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39499,717,440 - 99,769,985 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl499,717,435 - 99,769,985 (+)EnsemblGRCm39 Ensembl
GRCm38499,829,445 - 99,912,788 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl499,829,198 - 99,912,788 (+)EnsemblGRCm38mm10GRCm38
MGSCv37499,550,648 - 99,585,390 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36499,375,977 - 99,410,717 (+)NCBIMGSCv36mm8
Celera498,205,751 - 98,257,285 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map445.71NCBI
Efcab7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85119,640,841 - 119,691,566 (+)NCBIGRCr8
mRatBN7.25114,525,403 - 114,576,130 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5114,525,167 - 114,576,129 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5117,081,727 - 117,132,281 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05118,807,048 - 118,857,604 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05118,869,583 - 118,920,138 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05118,673,835 - 118,724,581 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5118,541,979 - 118,724,581 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05122,591,957 - 122,629,531 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.05122,470,265 - 122,472,469 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45120,525,527 - 120,576,068 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5113,073,505 - 113,124,027 (+)NCBICelera
Cytogenetic Map5q33NCBI
EFCAB7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21163,281,065 - 163,330,396 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11162,431,674 - 162,480,895 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0162,779,937 - 62,829,252 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1164,588,691 - 64,650,754 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,588,691 - 64,638,005 (+)Ensemblpanpan1.1panPan2
EFCAB7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1546,598,411 - 46,645,651 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl546,597,432 - 46,645,592 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha546,659,205 - 46,706,543 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0546,778,686 - 46,826,225 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl546,778,693 - 46,826,040 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1546,740,499 - 46,787,825 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0546,686,845 - 46,734,339 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0546,944,328 - 46,991,657 (-)NCBIUU_Cfam_GSD_1.0
Efcab7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505876,776,487 - 76,822,052 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366921,091,613 - 1,137,671 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366921,091,872 - 1,137,426 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EFCAB7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6148,851,183 - 148,994,952 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16148,939,050 - 148,997,790 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26137,259,099 - 137,317,498 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EFCAB7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12069,504,889 - 69,564,538 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2069,517,867 - 69,562,294 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603347,896,943 - 47,947,384 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Efcab7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474230,605,865 - 30,637,383 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474230,607,384 - 30,639,187 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000013636   ⟹   ENSCLAP00000013482
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542326,474,568 - 26,509,196 (-)Ensembl
RefSeq Acc Id: XM_005385327   ⟹   XP_005385384
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542326,473,310 - 26,510,703 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005385328   ⟹   XP_005385385
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542326,473,310 - 26,510,685 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005385329   ⟹   XP_005385386
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542326,473,310 - 26,510,686 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005385330   ⟹   XP_005385387
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542326,473,310 - 26,510,704 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005385384 (Get FASTA)   NCBI Sequence Viewer  
  XP_005385385 (Get FASTA)   NCBI Sequence Viewer  
  XP_005385386 (Get FASTA)   NCBI Sequence Viewer  
  XP_005385387 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000013482
  ENSCLAP00000013482.1
RefSeq Acc Id: XP_005385387   ⟸   XM_005385330
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005385384   ⟸   XM_005385327
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VG50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005385385   ⟸   XM_005385328
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VG50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005385386   ⟸   XM_005385329
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VG50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000013482   ⟸   ENSCLAT00000013636
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009320 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013636 ENTREZGENE
  ENSCLAT00000013636.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
NCBI Gene Efcab7 ENTREZGENE
PANTHER EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 UniProtKB/TrEMBL
  EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 UniProtKB/TrEMBL
Pfam EF-hand_5 UniProtKB/TrEMBL
  EF-hand_7 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A8C2VG50 ENTREZGENE, UniProtKB/TrEMBL