Prrg2 (proline rich and Gla domain 2) - Rat Genome Database

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Gene: Prrg2 (proline rich and Gla domain 2) Chinchilla lanigera
Analyze
Symbol: Prrg2
Name: proline rich and Gla domain 2
RGD ID: 8818651
Description: ASSOCIATED WITH developmental and epileptic encephalopathy 12 (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: proline rich Gla (G-carboxyglutamic acid) 2; transmembrane gamma-carboxyglutamic acid protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,280,192 - 1,285,734 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,279,601 - 1,287,182 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Prrg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,280,192 - 1,285,734 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,279,601 - 1,287,182 (-)NCBIChiLan1.0ChiLan1.0
PRRG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,580,617 - 49,591,004 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,580,646 - 49,591,004 (+)EnsemblGRCh38hg38GRCh38
GRCh371950,084,573 - 50,094,261 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,778,280 - 54,786,008 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,778,279 - 54,786,003NCBI
Celera1946,953,927 - 46,963,605 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,461,623 - 46,471,387 (+)NCBIHuRef
CHM1_11950,086,368 - 50,096,057 (+)NCBICHM1_1
T2T-CHM13v2.01952,580,649 - 52,591,029 (+)NCBIT2T-CHM13v2.0
Prrg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,703,008 - 44,711,828 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,703,008 - 44,712,101 (-)EnsemblGRCm39 Ensembl
GRCm38745,053,584 - 45,062,672 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,053,584 - 45,062,677 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,308,974 - 52,317,022 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,921,646 - 44,929,694 (-)NCBIMGSCv36mm8
Celera740,505,750 - 40,513,793 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.1NCBI
Prrg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,670,748 - 104,679,852 (-)NCBIGRCr8
mRatBN7.2195,534,276 - 95,543,364 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,534,290 - 95,543,425 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,920,581 - 100,928,019 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,393,252 - 109,400,690 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,683,652 - 102,691,090 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,046,621 - 101,055,608 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,046,563 - 101,054,851 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,111,580 - 102,120,584 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,526,091 - 95,533,411 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,603,840 - 95,611,512 (-)NCBI
Celera189,796,266 - 89,803,702 (-)NCBICelera
Cytogenetic Map1q22NCBI
PRRG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,698,898 - 55,708,028 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,619,731 - 57,629,319 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,595,628 - 46,605,897 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,516,413 - 55,525,229 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,516,413 - 55,525,229 (+)Ensemblpanpan1.1panPan2
PRRG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11106,931,658 - 106,938,321 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1106,932,232 - 106,936,422 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,514,939 - 106,522,854 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,451,745 - 107,459,689 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,452,319 - 107,458,086 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,124,812 - 107,132,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,766,915 - 106,774,825 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,608,044 - 107,615,973 (-)NCBIUU_Cfam_GSD_1.0
Prrg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,801,833 - 21,808,351 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,421,015 - 3,426,541 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,420,457 - 3,426,541 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRRG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,635,929 - 54,644,323 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,635,980 - 54,644,653 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,364,945 - 50,373,362 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRRG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,754,739 - 42,765,349 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,755,353 - 42,765,402 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,694,775 - 22,705,271 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prrg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248324,667,957 - 4,674,386 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,667,957 - 4,674,949 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000010966   ⟹   ENSCLAP00000010833
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555591,280,192 - 1,285,734 (-)Ensembl
RefSeq Acc Id: XM_005412865   ⟹   XP_005412922
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,279,601 - 1,287,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013508986   ⟹   XP_013364440
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,279,601 - 1,287,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013508987   ⟹   XP_013364441
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,279,601 - 1,286,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013508988   ⟹   XP_013364442
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,280,619 - 1,286,454 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005412922 (Get FASTA)   NCBI Sequence Viewer  
  XP_013364440 (Get FASTA)   NCBI Sequence Viewer  
  XP_013364441 (Get FASTA)   NCBI Sequence Viewer  
  XP_013364442 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000010833
  ENSCLAP00000010833.1
RefSeq Acc Id: XP_005412922   ⟸   XM_005412865
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V649 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013364440   ⟸   XM_013508986
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V649 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013364441   ⟸   XM_013508987
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V649 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013364442   ⟸   XM_013508988
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000010833   ⟸   ENSCLAT00000010966
Protein Domains
Gla


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007479 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010966 ENTREZGENE
  ENSCLAT00000010966.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.740.10 UniProtKB/TrEMBL
InterPro Coagulation_fac-like_Gla_dom UniProtKB/TrEMBL
  GLA-like_dom_SF UniProtKB/TrEMBL
  GLA_domain UniProtKB/TrEMBL
NCBI Gene Prrg2 ENTREZGENE
PANTHER COAGULATION FACTOR UniProtKB/TrEMBL
  TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 2 UniProtKB/TrEMBL
Pfam Gla UniProtKB/TrEMBL
PRINTS GLABLOOD UniProtKB/TrEMBL
PROSITE GLA_1 UniProtKB/TrEMBL
  GLA_2 UniProtKB/TrEMBL
SMART GLA UniProtKB/TrEMBL
Superfamily-SCOP SSF57630 UniProtKB/TrEMBL
UniProt A0A8C2V649 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Prrg2  proline rich and Gla domain 2    proline rich Gla (G-carboxyglutamic acid) 2  Symbol and/or name change 5135510 APPROVED