Lrpprc (leucine rich pentatricopeptide repeat containing) - Rat Genome Database

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Gene: Lrpprc (leucine rich pentatricopeptide repeat containing) Chinchilla lanigera
Analyze
Symbol: Lrpprc
Name: leucine rich pentatricopeptide repeat containing
RGD ID: 8806302
Description: ENCODES a protein that exhibits actin filament binding (ortholog); beta-tubulin binding (ortholog); RNA binding (ortholog); INVOLVED IN mitochondrial RNA catabolic process (ortholog); negative regulation of mitochondrial RNA catabolic process (ortholog); regulation of mitochondrial translation (ortholog); PARTICIPATES IN CRM1 export pathway; ASSOCIATED WITH congenital myasthenic syndrome (ortholog); congenital myasthenic syndrome 10 (ortholog); epilepsy (ortholog); FOUND IN condensed nuclear chromosome (ortholog); cytoplasm (ortholog); cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich pentatricopeptide repeat containing; leucine-rich PPR motif-containing protein, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544111,012,910 - 11,116,965 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Lrpprc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544111,012,910 - 11,116,965 (-)NCBIChiLan1.0ChiLan1.0
LRPPRC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38243,886,224 - 43,996,265 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl243,886,224 - 43,996,226 (-)EnsemblGRCh38hg38GRCh38
GRCh37244,113,363 - 44,223,128 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36243,968,391 - 44,076,648 (-)NCBINCBI36Build 36hg18NCBI36
Build 34244,026,537 - 44,134,795NCBI
Celera243,952,087 - 44,062,100 (-)NCBICelera
Cytogenetic Map2p21NCBI
HuRef243,849,689 - 43,959,564 (-)NCBIHuRef
CHM1_1244,042,771 - 44,152,581 (-)NCBICHM1_1
T2T-CHM13v2.0243,891,557 - 44,001,630 (-)NCBIT2T-CHM13v2.0
Lrpprc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391785,012,675 - 85,098,214 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1785,012,675 - 85,098,217 (-)EnsemblGRCm39 Ensembl
GRCm381784,705,247 - 84,790,786 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1784,705,247 - 84,790,789 (-)EnsemblGRCm38mm10GRCm38
MGSCv371785,104,587 - 85,190,126 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361784,613,573 - 84,698,841 (-)NCBIMGSCv36mm8
Celera1789,073,226 - 89,158,633 (-)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1755.02NCBI
Lrpprc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8615,612,638 - 15,695,113 (+)NCBIGRCr8
mRatBN7.269,859,816 - 9,942,294 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl69,859,867 - 9,942,293 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx610,148,236 - 10,230,722 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0610,457,631 - 10,540,115 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.069,979,042 - 10,061,742 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.067,984,043 - 8,066,874 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl67,984,019 - 8,066,868 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.067,919,928 - 8,001,949 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.468,086,606 - 8,168,261 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.168,086,606 - 8,168,261 (-)NCBI
Celera69,581,533 - 9,663,935 (+)NCBICelera
Cytogenetic Map6q12NCBI
LRPPRC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21282,421,380 - 82,530,685 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A82,425,351 - 82,535,405 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A43,975,949 - 44,083,846 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A44,914,578 - 45,021,434 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A44,914,578 - 45,021,434 (-)Ensemblpanpan1.1panPan2
LRPPRC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11046,325,312 - 46,438,376 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1046,327,223 - 46,438,342 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1046,188,975 - 46,300,206 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01047,205,831 - 47,317,113 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1047,203,961 - 47,317,132 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11046,914,258 - 47,025,488 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01047,203,848 - 47,313,376 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01047,387,584 - 47,498,808 (-)NCBIUU_Cfam_GSD_1.0
Lrpprc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629236,532,488 - 36,638,283 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365087,961,079 - 8,068,228 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRPPRC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl396,474,549 - 96,595,143 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1396,474,510 - 96,590,706 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23102,630,054 - 102,744,878 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LRPPRC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11463,263,101 - 63,380,607 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604548,506,466 - 48,623,733 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrpprc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473825,338,098 - 25,452,676 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473825,340,588 - 25,452,593 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013517542   ⟹   XP_013372996
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544111,012,910 - 11,116,965 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013372996 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007399
  ENSCLAP00000007399.1
Reference Protein Sequences
RefSeq Acc Id: XP_013372996   ⟸   XM_013517542
- UniProtKB: A0A8C2V328 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Pentacotripeptide-repeat region of PRORP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005203 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007516 ENTREZGENE
  ENSCLAT00000007516.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro LRP130 UniProtKB/TrEMBL
  Pentatricopeptide_repeat UniProtKB/TrEMBL
  PPR_long UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
NCBI Gene Lrpprc ENTREZGENE
PANTHER LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR46669 UniProtKB/TrEMBL
Pfam PPR UniProtKB/TrEMBL
  PPR_3 UniProtKB/TrEMBL
  PPR_long UniProtKB/TrEMBL
PROSITE PPR UniProtKB/TrEMBL
UniProt A0A8C2V328 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Lrpprc  leucine rich pentatricopeptide repeat containing    leucine-rich pentatricopeptide repeat containing  Symbol and/or name change 5135510 APPROVED