Nek8 (NIMA related kinase 8) - Rat Genome Database

Name: Nek8
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Nek8 (NIMA related kinase 8) Chinchilla lanigera

Analyze

Symbol:

Nek8

Name:

NIMA related kinase 8

RGD ID:

8778587

Description:

INVOLVED IN animal organ morphogenesis (ortholog); determination of left/right symmetry (ortholog); heart development (ortholog); ASSOCIATED WITH autosomal recessive polycystic kidney disease (ortholog); genetic disease (ortholog); kidney disease (ortholog); FOUND IN ciliary base (ortholog); ciliary inversin compartment (ortholog); cilium (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

NIMA-related kinase 8; serine/threonine-protein kinase Nek8

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	4,417,773 - 4,427,885 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	4,417,773 - 4,427,885 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive polycystic kidney disease (ISO)

genetic disease (ISO)

kidney disease (ISO)

nephronophthisis 9 (ISO)

Pancreatic Neoplasms (ISO)

primary ovarian insufficiency (ISO)

Renal-Hepatic-Pancreatic Dysplasia 2 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ morphogenesis (ISO)

determination of left/right symmetry (ISO)

heart development (ISO)

regulation of hippo signaling (ISO)

Cellular Component

ciliary base (ISO)

ciliary inversin compartment (ISO)

cilium (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Nek8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	4,417,773 - 4,427,885 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	4,417,773 - 4,427,885 (-)	NCBI	ChiLan1.0	ChiLan1.0

NEK8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	28,728,788 - 28,743,455 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	28,725,897 - 28,743,455 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	27,055,806 - 27,070,473 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	24,079,959 - 24,093,911 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	24,079,958 - 24,093,911	NCBI
Celera	17	23,914,995 - 23,928,979 (+)	NCBI		Celera
Cytogenetic Map	17	q11.2	NCBI
HuRef	17	23,264,730 - 23,278,592 (+)	NCBI		HuRef
CHM1_1	17	27,118,302 - 27,132,262 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	29,671,595 - 29,686,240 (+)	NCBI		T2T-CHM13v2.0

Nek8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	78,056,932 - 78,067,501 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	78,056,932 - 78,067,501 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	78,166,106 - 78,176,695 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	78,166,106 - 78,176,675 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	77,979,608 - 77,990,168 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	77,982,715 - 77,992,861 (-)	NCBI		MGSCv36	mm8
Celera	11	85,665,979 - 85,676,539 (-)	NCBI		Celera
Cytogenetic Map	11	B5	NCBI
cM Map	11	46.74	NCBI

Nek8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	63,558,940 - 63,570,954 (-)	NCBI		GRCr8
mRatBN7.2	10	63,060,868 - 63,073,546 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	63,061,253 - 63,072,416 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	67,693,525 - 67,704,703 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	67,198,879 - 67,210,057 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	62,669,900 - 62,681,011 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	65,404,489 - 65,439,059 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	65,425,771 - 65,437,143 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	66,196,993 - 66,230,588 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	64,458,886 - 64,470,044 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	64,472,568 - 64,483,018 (+)	NCBI
Celera	10	62,038,910 - 62,050,078 (-)	NCBI		Celera
Cytogenetic Map	10	q25	NCBI

NEK8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	35,716,348 - 35,732,975 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	37,596,329 - 37,613,488 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	28,033,001 - 28,048,157 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	28,539,621 - 28,553,282 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	28,539,621 - 28,550,860 (-)	Ensembl	panpan1.1		panPan2

NEK8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	42,923,208 - 42,933,083 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	42,923,288 - 42,932,352 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	42,078,973 - 42,088,848 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	43,741,379 - 43,751,253 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	43,741,425 - 43,751,220 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	42,524,530 - 42,534,168 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	42,816,751 - 42,826,387 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	42,895,059 - 42,904,934 (+)	NCBI		UU_Cfam_GSD_1.0

Nek8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	42,060,781 - 42,074,138 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936538	4,938,708 - 4,952,194 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936538	4,938,739 - 4,952,083 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NEK8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	44,965,116 - 44,975,083 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	44,963,095 - 44,975,092 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	46,948,058 - 46,960,030 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NEK8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	22,495,745 - 22,506,782 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666075	7,613,680 - 7,627,632 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nek8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	1,303,308 - 1,314,188 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	1,303,283 - 1,314,188 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005402716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013503384	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013503385	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01056937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDI01002899	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000016383 ⟹ ENSCLAP00000016219

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955481	4,417,773 - 4,427,885 (-)	Ensembl

RefSeq Acc Id:

XM_005402716 ⟹ XP_005402773

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955481	4,417,773 - 4,427,885 (-)	NCBI

Sequence:

show sequence

GAGCGGGCAGGTCCGCGCATGCGCCGCCTGAAGGGTTCCGGAAGCATATGTCTGAGAAATGAGA
TGGAGAAGTACGAGCGGATCCGAGTGGTGGGGAGAGGTGCTTTCGGGATTGTGCACCTGTGTCT
GCGAAAGGCTGACCAGAAGCTGGTCATCATCAAACAGATCCCAGTGGAACAGATGACCAAGGAG
GAACGGCAGGCAGCCCAGAATGAGTGCCAGGTGCTCAAGCTGCTCAATCACCCCAATGTCATTG
AATACTATGAGAACTTCCTGGAGGACAAGGCTCTTATGATTGCCATGGAATATGCACCAGGTGG
CACTCTGGCTGAGTTCATCCAGAAGCGCTGCAATTCTCTGCTAGAGGAGGAGACCATCCTGCAC
TTCTTTGTGCAGATTCTGCTTGCGCTACATCATGTACACACCCACCTCATCCTGCACCGGGACC
TCAAGACCCAGAATATCCTTCTTGACAAACACCGCATGGTCGTCAAGATTGGTGACTTTGGCAT
CTCCAAGATCCTTAGCAGCAAGAGCAAGGCTTACACGGTAGTGGGTACTCCGTGCTACATCTCC
CCTGAGCTGTGTGAAGGCAAGCCGTATAACCAGAAGAGTGACATCTGGGCCCTGGGCTGTGTCC
TCTATGAGCTGGCCAGTCTCAAGAGAGCTTTCGAGGCTGCAAACCTGCCAGCACTGGTACTAAA
GATCATGAGCGGCACTTTTGCACCCATCTCTGACCGGTACAGCCCAGAGCTGCGCCAGCTGGTC
CTGAGTCTGCTGAGCCTGGAGCCTGCACAGCGGCCACCACTAAGCCACATCATGGCGCAGCCTC
TCTGCATCCGGGCCCTCCTCAACCTGCACACTGACGTGGGCAGCATCCGAATGCGGAGGGCAGA
GAAGTCTCTGGGTCCAGGACCACCCATTGTACCTGGCAACACAGGGAGTAGGACCAGCAGTGCC
CGCTGCAGGAGTGTTCTCCGGGGACCCATGAGGCCGGCCATCCCACCACCACTGTCATCAGTGT
ACGCATGGGGGGGTGGGCTGAGCACCCCCCTGCGGCTGCCAATGCTCAACACAGAGGTGATCCA
GGTGGCTGTAGGGCGCACACAGAAGGCTGGCGTCACACGCTCTGGGCGCCTCATCCTGTGGGAG
GCCCCACCCCTAGGATCAGGTGCAGGTGCCCTCCTCCCAGGGGCAGTGGAGCAGCCCCAGCCCC
AGTTCATCTCACGTTTCCTGGAGGGCCAGTCAGGCGTGACCATCAAGCATGTGGCCTGCGGGGA
CCTCTTCACGGCCTGCCTGACTGATCGCGGCATCATCATGACATTTGGCAGTGGCAGCAACGGG
TGCCTAGGCCATGGCAGCCTCACTGACATCAGCCAGCCCACCATTGTGGAGGCCCTGCTGGGCT
ATGAGATGGTGCAGGTGGCCTGTGGGGCCTCTCATGTGCTGGCCCTGTCCACAGAGCGAGAACT
GTTTGCCTGGGGCCGCGGAGATGGTGGCAGGCTGGGACTAGGCACCAGAGAGTCTCATAGCTGC
CCCCAACAGGTGCCCATGCCCCCAGGACAGGAGGCCCAGCGGGTTGTATGTGGCATTGATTCTT
CCATGATCCTCACTGTGCCTGGCCGAGCCCTGGCCTGTGGGAGCAACAGGTTCAACAAGCTGGG
CCTGGACCACCTCTCCCTCGGGGAGGAGCCTGCCCCCCAGCAGCAAGTAGAGGAGGCCCTGGGC
TTCACACCACTACGCTCCGCACCCCTGGACCAGGAGTCCTTGCTGAGTGTGGACCTGGGTACTG
CTCACTCGGCTGCTGTGACTGCCTCGGGTGACTGCTACACTTTTGGCAGCAATCAGCATGGGCA
GTTGGGCACCAATGCCCGCCGGGGCAGCCGAGCACCCTGTCAGGTCCTAGGCCTTGAGGGGATC
AAGATGGCCATGGTGGCCTGTGGAGATGCCTTCACTGTAGCTATTGGGGCAGAGGGTGAAGTGT
ACTCTTGGGGCAAAGGGGCCCGAGGTCGACTGGGAAGGAGGGATGAGGATGCTGGACTCCCTCG
GCCAGTGCAGCTGGATGAGACTCACCCTTATGCAGTGACTTCTGTGTCTTGTTGCCATGGAAAC
ACTCTCCTGGCAGTGCGCCACATCACAGATGAGCCAGTCCCTCCCTGAGGCACCAGGATGCACC
TCTGAACCACCCTGATACAGCAATGCTTCTCTGCCTAAGTGTTCTGGAGAAGTGCTTCTGCACT
GTGGAATGGTGGGGAAGGGCTGGGGAAGCTTTACTCTGCTCTGGCCCTGGGTGGAGAAATCTCA
ACCACTCTGGTCTCCCTCCCTGCCCCTCTTTACCCTCCCTACTCACTCTTCCCTCACGGTGTCC
CCAGGTCCAGCCTGGCTGGAGCTGGCATTTCACACTAGGACTACCTTTGGCAGCTGGTCTCTAG
AGCCTTGCTGAGAGGCATCTGTGGCTTTCCTCAGTTCCTGTCCTGCCCCCTGCCCAGTTAGAAA
ATACGTTTCCCTGCAGGGGTTGATGGCCTGTGATCTTAGCTATTACTGTTCTCAGTTGCTGAGG
CAGGAGGATCACCAGTTAAAGTCTAGCCTGAGCAGCTTAGTGAGACATTGTTTCAAAAAAAAGT
TTGCACCAGTGGGAGATAGGCGCCATGCTTCACAGCAGAGCAAGTCAAGGCCTGCCTGGACTGG
CCATCAGTCCTGCCTAGCCTTTGCATGGCCTGGGGCAGGGAGGTCCAAGGGACCCCGTCACCCC
TTTATCCTGAGGCAGGATTAACACAACCTCCGTGAGCCTTCCTTCCCCTGCCAGAGTGCTAGAG
TCCGCAAGTGGCTGCAGAGAGGATCCTTGGCTAGGTTGCCCATCACCCCAAGTCTTTGCCCAGA
CCCAGGTTTGGAGTAAAGGTAGCTAGTGAGACCAGACCAGTTTCTCAAAGGACTGAAAGTAGCG
CTAATAAAAAATAGCAACCGCC

hide sequence

RefSeq Acc Id:

XM_013503384 ⟹ XP_013358838

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955481	4,417,773 - 4,427,573 (-)	NCBI

Sequence:

show sequence

GCTGGGTGTGAGGTTCCTCGTTCTTTCCTTGAACAGATGTTGAGTGCCGGCTGCAAGAGTCCGG
CTCTGGGCGCTGGGTGTAAAGTTATGACCAAACAGGATTGTGCACCTGTGTCTGCGAAAGGCTG
ACCAGAAGCTGGTCATCATCAAACAGATCCCAGTGGAACAGATGACCAAGGAGGAACGGCAGGC
AGCCCAGAATGAGTGCCAGGTGCTCAAGCTGCTCAATCACCCCAATGTCATTGAATACTATGAG
AACTTCCTGGAGGACAAGGCTCTTATGATTGCCATGGAATATGCACCAGGTGGCACTCTGGCTG
AGTTCATCCAGAAGCGCTGCAATTCTCTGCTAGAGGAGGAGACCATCCTGCACTTCTTTGTGCA
GATTCTGCTTGCGCTACATCATGTACACACCCACCTCATCCTGCACCGGGACCTCAAGACCCAG
AATATCCTTCTTGACAAACACCGCATGGTCGTCAAGATTGGTGACTTTGGCATCTCCAAGATCC
TTAGCAGCAAGAGCAAGGCTTACACGGTAGTGGGTACTCCGTGCTACATCTCCCCTGAGCTGTG
TGAAGGCAAGCCGTATAACCAGAAGAGTGACATCTGGGCCCTGGGCTGTGTCCTCTATGAGCTG
GCCAGTCTCAAGAGAGCTTTCGAGGCTGCAAACCTGCCAGCACTGGTACTAAAGATCATGAGCG
GCACTTTTGCACCCATCTCTGACCGGTACAGCCCAGAGCTGCGCCAGCTGGTCCTGAGTCTGCT
GAGCCTGGAGCCTGCACAGCGGCCACCACTAAGCCACATCATGGCGCAGCCTCTCTGCATCCGG
GCCCTCCTCAACCTGCACACTGACGTGGGCAGCATCCGAATGCGGAGGGCAGAGAAGTCTCTGG
GTCCAGGACCACCCATTGTACCTGGCAACACAGGGAGTAGGACCAGCAGTGCCCGCTGCAGGAG
TGTTCTCCGGGGACCCATGAGGCCGGCCATCCCACCACCACTGTCATCAGTGTACGCATGGGGG
GGTGGGCTGAGCACCCCCCTGCGGCTGCCAATGCTCAACACAGAGGTGATCCAGGTGGCTGTAG
GGCGCACACAGAAGGCTGGCGTCACACGCTCTGGGCGCCTCATCCTGTGGGAGGCCCCACCCCT
AGGATCAGGTGCAGGTGCCCTCCTCCCAGGGGCAGTGGAGCAGCCCCAGCCCCAGTTCATCTCA
CGTTTCCTGGAGGGCCAGTCAGGCGTGACCATCAAGCATGTGGCCTGCGGGGACCTCTTCACGG
CCTGCCTGACTGATCGCGGCATCATCATGACATTTGGCAGTGGCAGCAACGGGTGCCTAGGCCA
TGGCAGCCTCACTGACATCAGCCAGCCCACCATTGTGGAGGCCCTGCTGGGCTATGAGATGGTG
CAGGTGGCCTGTGGGGCCTCTCATGTGCTGGCCCTGTCCACAGAGCGAGAACTGTTTGCCTGGG
GCCGCGGAGATGGTGGCAGGCTGGGACTAGGCACCAGAGAGTCTCATAGCTGCCCCCAACAGGT
GCCCATGCCCCCAGGACAGGAGGCCCAGCGGGTTGTATGTGGCATTGATTCTTCCATGATCCTC
ACTGTGCCTGGCCGAGCCCTGGCCTGTGGGAGCAACAGGTTCAACAAGCTGGGCCTGGACCACC
TCTCCCTCGGGGAGGAGCCTGCCCCCCAGCAGCAAGTAGAGGAGGCCCTGGGCTTCACACCACT
ACGCTCCGCACCCCTGGACCAGGAGTCCTTGCTGAGTGTGGACCTGGGTACTGCTCACTCGGCT
GCTGTGACTGCCTCGGGTGACTGCTACACTTTTGGCAGCAATCAGCATGGGCAGTTGGGCACCA
ATGCCCGCCGGGGCAGCCGAGCACCCTGTCAGGTCCTAGGCCTTGAGGGGATCAAGATGGCCAT
GGTGGCCTGTGGAGATGCCTTCACTGTAGCTATTGGGGCAGAGGGTGAAGTGTACTCTTGGGGC
AAAGGGGCCCGAGGTCGACTGGGAAGGAGGGATGAGGATGCTGGACTCCCTCGGCCAGTGCAGC
TGGATGAGACTCACCCTTATGCAGTGACTTCTGTGTCTTGTTGCCATGGAAACACTCTCCTGGC
AGTGCGCCACATCACAGATGAGCCAGTCCCTCCCTGAGGCACCAGGATGCACCTCTGAACCACC
CTGATACAGCAATGCTTCTCTGCCTAAGTGTTCTGGAGAAGTGCTTCTGCACTGTGGAATGGTG
GGGAAGGGCTGGGGAAGCTTTACTCTGCTCTGGCCCTGGGTGGAGAAATCTCAACCACTCTGGT
CTCCCTCCCTGCCCCTCTTTACCCTCCCTACTCACTCTTCCCTCACGGTGTCCCCAGGTCCAGC
CTGGCTGGAGCTGGCATTTCACACTAGGACTACCTTTGGCAGCTGGTCTCTAGAGCCTTGCTGA
GAGGCATCTGTGGCTTTCCTCAGTTCCTGTCCTGCCCCCTGCCCAGTTAGAAAATACGTTTCCC
TGCAGGGGTTGATGGCCTGTGATCTTAGCTATTACTGTTCTCAGTTGCTGAGGCAGGAGGATCA
CCAGTTAAAGTCTAGCCTGAGCAGCTTAGTGAGACATTGTTTCAAAAAAAAGTTTGCACCAGTG
GGAGATAGGCGCCATGCTTCACAGCAGAGCAAGTCAAGGCCTGCCTGGACTGGCCATCAGTCCT
GCCTAGCCTTTGCATGGCCTGGGGCAGGGAGGTCCAAGGGACCCCGTCACCCCTTTATCCTGAG
GCAGGATTAACACAACCTCCGTGAGCCTTCCTTCCCCTGCCAGAGTGCTAGAGTCCGCAAGTGG
CTGCAGAGAGGATCCTTGGCTAGGTTGCCCATCACCCCAAGTCTTTGCCCAGACCCAGGTTTGG
AGTAAAGGTAGCTAGTGAGACCAGACCAGTTTCTCAAAGGACTGAAAGTAGCGCTAATAAAAAA
TAGCAACCGCC

hide sequence

RefSeq Acc Id:

XM_013503385 ⟹ XP_013358839

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955481	4,417,773 - 4,427,885 (-)	NCBI

Sequence:

show sequence

GAGCGGGCAGGTCCGCGCATGCGCCGCCTGAAGGGTTCCGGAAGCATATGTCTGAGAAATGAGA
TGGAGAAGTACGAGCGGATCCGAGTGGTGGGGAGAGGTGCTTTCGGGTGGCACTCTGGCTGAGT
TCATCCAGAAGCGCTGCAATTCTCTGCTAGAGGAGGAGACCATCCTGCACTTCTTTGTGCAGAT
TCTGCTTGCGCTACATCATGTACACACCCACCTCATCCTGCACCGGGACCTCAAGACCCAGAAT
ATCCTTCTTGACAAACACCGCATGGTCGTCAAGATTGGTGACTTTGGCATCTCCAAGATCCTTA
GCAGCAAGAGCAAGGCTTACACGGTAGTGGGTACTCCGTGCTACATCTCCCCTGAGCTGTGTGA
AGGCAAGCCGTATAACCAGAAGAGTGACATCTGGGCCCTGGGCTGTGTCCTCTATGAGCTGGCC
AGTCTCAAGAGAGCTTTCGAGGCTGCAAACCTGCCAGCACTGGTACTAAAGATCATGAGCGGCA
CTTTTGCACCCATCTCTGACCGGTACAGCCCAGAGCTGCGCCAGCTGGTCCTGAGTCTGCTGAG
CCTGGAGCCTGCACAGCGGCCACCACTAAGCCACATCATGGCGCAGCCTCTCTGCATCCGGGCC
CTCCTCAACCTGCACACTGACGTGGGCAGCATCCGAATGCGGAGGGCAGAGAAGTCTCTGGGTC
CAGGACCACCCATTGTACCTGGCAACACAGGGAGTAGGACCAGCAGTGCCCGCTGCAGGAGTGT
TCTCCGGGGACCCATGAGGCCGGCCATCCCACCACCACTGTCATCAGTGTACGCATGGGGGGGT
GGGCTGAGCACCCCCCTGCGGCTGCCAATGCTCAACACAGAGGTGATCCAGGTGGCTGTAGGGC
GCACACAGAAGGCTGGCGTCACACGCTCTGGGCGCCTCATCCTGTGGGAGGCCCCACCCCTAGG
ATCAGGTGCAGGTGCCCTCCTCCCAGGGGCAGTGGAGCAGCCCCAGCCCCAGTTCATCTCACGT
TTCCTGGAGGGCCAGTCAGGCGTGACCATCAAGCATGTGGCCTGCGGGGACCTCTTCACGGCCT
GCCTGACTGATCGCGGCATCATCATGACATTTGGCAGTGGCAGCAACGGGTGCCTAGGCCATGG
CAGCCTCACTGACATCAGCCAGCCCACCATTGTGGAGGCCCTGCTGGGCTATGAGATGGTGCAG
GTGGCCTGTGGGGCCTCTCATGTGCTGGCCCTGTCCACAGAGCGAGAACTGTTTGCCTGGGGCC
GCGGAGATGGTGGCAGGCTGGGACTAGGCACCAGAGAGTCTCATAGCTGCCCCCAACAGGTGCC
CATGCCCCCAGGACAGGAGGCCCAGCGGGTTGTATGTGGCATTGATTCTTCCATGATCCTCACT
GTGCCTGGCCGAGCCCTGGCCTGTGGGAGCAACAGGTTCAACAAGCTGGGCCTGGACCACCTCT
CCCTCGGGGAGGAGCCTGCCCCCCAGCAGCAAGTAGAGGAGGCCCTGGGCTTCACACCACTACG
CTCCGCACCCCTGGACCAGGAGTCCTTGCTGAGTGTGGACCTGGGTACTGCTCACTCGGCTGCT
GTGACTGCCTCGGGTGACTGCTACACTTTTGGCAGCAATCAGCATGGGCAGTTGGGCACCAATG
CCCGCCGGGGCAGCCGAGCACCCTGTCAGGTCCTAGGCCTTGAGGGGATCAAGATGGCCATGGT
GGCCTGTGGAGATGCCTTCACTGTAGCTATTGGGGCAGAGGGTGAAGTGTACTCTTGGGGCAAA
GGGGCCCGAGGTCGACTGGGAAGGAGGGATGAGGATGCTGGACTCCCTCGGCCAGTGCAGCTGG
ATGAGACTCACCCTTATGCAGTGACTTCTGTGTCTTGTTGCCATGGAAACACTCTCCTGGCAGT
GCGCCACATCACAGATGAGCCAGTCCCTCCCTGAGGCACCAGGATGCACCTCTGAACCACCCTG
ATACAGCAATGCTTCTCTGCCTAAGTGTTCTGGAGAAGTGCTTCTGCACTGTGGAATGGTGGGG
AAGGGCTGGGGAAGCTTTACTCTGCTCTGGCCCTGGGTGGAGAAATCTCAACCACTCTGGTCTC
CCTCCCTGCCCCTCTTTACCCTCCCTACTCACTCTTCCCTCACGGTGTCCCCAGGTCCAGCCTG
GCTGGAGCTGGCATTTCACACTAGGACTACCTTTGGCAGCTGGTCTCTAGAGCCTTGCTGAGAG
GCATCTGTGGCTTTCCTCAGTTCCTGTCCTGCCCCCTGCCCAGTTAGAAAATACGTTTCCCTGC
AGGGGTTGATGGCCTGTGATCTTAGCTATTACTGTTCTCAGTTGCTGAGGCAGGAGGATCACCA
GTTAAAGTCTAGCCTGAGCAGCTTAGTGAGACATTGTTTCAAAAAAAAGTTTGCACCAGTGGGA
GATAGGCGCCATGCTTCACAGCAGAGCAAGTCAAGGCCTGCCTGGACTGGCCATCAGTCCTGCC
TAGCCTTTGCATGGCCTGGGGCAGGGAGGTCCAAGGGACCCCGTCACCCCTTTATCCTGAGGCA
GGATTAACACAACCTCCGTGAGCCTTCCTTCCCCTGCCAGAGTGCTAGAGTCCGCAAGTGGCTG
CAGAGAGGATCCTTGGCTAGGTTGCCCATCACCCCAAGTCTTTGCCCAGACCCAGGTTTGGAGT
AAAGGTAGCTAGTGAGACCAGACCAGTTTCTCAAAGGACTGAAAGTAGCGCTAATAAAAAATAG
CAACCGCC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005402773	(Get FASTA)	NCBI Sequence Viewer
	XP_013358838	(Get FASTA)	NCBI Sequence Viewer
	XP_013358839	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000016219
	ENSCLAP00000016219.1

RefSeq Acc Id:	XP_005402773 ⟸ XM_005402716
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2VKS7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRRLKGSGSICLRNEMEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQ NECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQIL LALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEG KPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSL EPAQRPPLSHIMAQPLCIRALLNLHTDVGSIRMRRAEKSLGPGPPIVPGNTGSRTSSARCRSVL RGPMRPAIPPPLSSVYAWGGGLSTPLRLPMLNTEVIQVAVGRTQKAGVTRSGRLILWEAPPLGS GAGALLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGS LTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDGGRLGLGTRESHSCPQQVPM PPGQEAQRVVCGIDSSMILTVPGRALACGSNRFNKLGLDHLSLGEEPAPQQQVEEALGFTPLRS APLDQESLLSVDLGTAHSAAVTASGDCYTFGSNQHGQLGTNARRGSRAPCQVLGLEGIKMAMVA CGDAFTVAIGAEGEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYAVTSVSCCHGNTLLAVR HITDEPVPP hide sequence

RefSeq Acc Id:	XP_013358839 ⟸ XM_013503385
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C2VKS7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRWRSTSGSEWWGEVLSGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKT QNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYE LASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCI RALLNLHTDVGSIRMRRAEKSLGPGPPIVPGNTGSRTSSARCRSVLRGPMRPAIPPPLSSVYAW GGGLSTPLRLPMLNTEVIQVAVGRTQKAGVTRSGRLILWEAPPLGSGAGALLPGAVEQPQPQFI SRFLEGQSGVTIKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEM VQVACGASHVLALSTERELFAWGRGDGGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMI LTVPGRALACGSNRFNKLGLDHLSLGEEPAPQQQVEEALGFTPLRSAPLDQESLLSVDLGTAHS AAVTASGDCYTFGSNQHGQLGTNARRGSRAPCQVLGLEGIKMAMVACGDAFTVAIGAEGEVYSW GKGARGRLGRRDEDAGLPRPVQLDETHPYAVTSVSCCHGNTLLAVRHITDEPVPP hide sequence

RefSeq Acc Id:	XP_013358838 ⟸ XM_013503384
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2VKS7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEE TILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTP CYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPEL RQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSIRMRRAEKSLGPGPPIVPGNTGSR TSSARCRSVLRGPMRPAIPPPLSSVYAWGGGLSTPLRLPMLNTEVIQVAVGRTQKAGVTRSGRL ILWEAPPLGSGAGALLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDLFTACLTDRGIIMTFGS GSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDGGRLGLGTRE SHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGRALACGSNRFNKLGLDHLSLGEEPAPQQQVE EALGFTPLRSAPLDQESLLSVDLGTAHSAAVTASGDCYTFGSNQHGQLGTNARRGSRAPCQVLG LEGIKMAMVACGDAFTVAIGAEGEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYAVTSVSC CHGNTLLAVRHITDEPVPP hide sequence

RefSeq Acc Id:

ENSCLAP00000016219 ⟸ ENSCLAT00000016383

Protein Domains

Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000011158	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000016383	ENTREZGENE
	ENSCLAT00000016383.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.30	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	RCC1/BLIP-II	UniProtKB/TrEMBL
	Reg_chr_condens	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
	STKc_Nek8	UniProtKB/TrEMBL
NCBI Gene	Nek8	ENTREZGENE
PANTHER	PROTEIN CBG16200	UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN KINASE NEK8	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
	RCC1	UniProtKB/TrEMBL
PRINTS	RCCNDNSATION	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
	RCC1_3	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50985	UniProtKB/TrEMBL
	SSF56112	UniProtKB/TrEMBL
UniProt	A0A8C2VKS7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Nek8	NIMA related kinase 8		NIMA-related kinase 8	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM