Rab38 (RAB38, member RAS oncogene family)

Gene: Rab38 (RAB38, member RAS oncogene family) Chinchilla lanigera

Analyze

Symbol:

Rab38

Name:

RAB38, member RAS oncogene family

RGD ID:

8753367

Description:

ENCODES a protein that exhibits AP-1 adaptor complex binding (ortholog); AP-2 adaptor complex binding (ortholog); AP-3 adaptor complex binding (ortholog); INVOLVED IN endosome to melanosome transport (ortholog); melanosome assembly (ortholog); mitochondrion organization (ortholog); ASSOCIATED WITH Albuminuria (ortholog); Hermansky-Pudlak syndrome (ortholog); intellectual disability (ortholog); FOUND IN cell body (ortholog); early endosome (ortholog); early endosome lumen (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ras-related protein Rab-38

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	5,158,261 - 5,215,698 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	5,158,860 - 5,214,108 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Albuminuria (ISO)

Hermansky-Pudlak syndrome (ISO)

intellectual disability (ISO)

platelet storage pool deficiency (ISO)

proteinuria (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endosome to melanosome transport (ISO)

melanosome assembly (ISO)

mitochondrion organization (ISO)

phagosome acidification (ISO)

platelet dense granule organization (ISO)

positive regulation of melanin biosynthetic process (ISO)

positive regulation of phosphatidylcholine biosynthetic process (ISO)

positive regulation of protein localization to cell periphery (ISO)

protein localization to membrane (ISO)

Cellular Component

cell body (ISO)

early endosome (ISO)

early endosome lumen (ISO)

lysosome (ISO)

melanosome (ISO)

melanosome membrane (ISO)

membrane (ISO)

mitochondria-associated endoplasmic reticulum membrane contact site (ISO)

mitochondrion (ISO)

perinuclear region of cytoplasm (ISO)

phagocytic vesicle (ISO)

vesicle (ISO)

Molecular Function

AP-1 adaptor complex binding (ISO)

AP-2 adaptor complex binding (ISO)

AP-3 adaptor complex binding (ISO)

BLOC-2 complex binding (ISO)

GTP binding (ISO)

GTP-dependent protein binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Rab38
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	5,158,261 - 5,215,698 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	5,158,860 - 5,214,108 (+)	NCBI	ChiLan1.0	ChiLan1.0

RAB38
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	87,803,715 - 88,175,443 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	88,113,251 - 88,175,443 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	87,846,419 - 87,908,611 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	87,486,079 - 87,548,247 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	87,486,078 - 87,548,247	NCBI
Celera	11	86,723,503 - 86,785,679 (+)	NCBI		Celera
Cytogenetic Map	11	q14.2	NCBI
HuRef	11	84,086,688 - 84,148,798 (-)	NCBI		HuRef
CHM1_1	11	87,729,200 - 87,791,404 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	87,746,041 - 88,094,423 (-)	NCBI		T2T-CHM13v2.0

Rab38
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	88,079,481 - 88,140,780 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	88,079,481 - 88,140,780 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	88,430,273 - 88,491,572 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	88,430,273 - 88,491,572 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	95,578,783 - 95,640,082 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	88,305,465 - 88,366,764 (+)	NCBI		MGSCv36	mm8
Celera	7	85,784,928 - 85,846,216 (+)	NCBI		Celera
Cytogenetic Map	7	D3	NCBI
cM Map	7	49.19	NCBI

Rab38
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	151,595,153 - 151,675,492 (+)	NCBI		GRCr8
mRatBN7.2	1	142,182,566 - 142,262,923 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	142,182,556 - 142,262,924 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	150,149,817 - 150,230,171 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	157,326,253 - 157,406,599 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	150,200,179 - 150,280,523 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	152,072,716 - 152,153,449 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	152,072,665 - 152,153,449 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	158,385,888 - 158,466,621 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	144,783,919 - 144,864,573 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	144,862,324 - 144,942,979 (+)	NCBI
Celera	1	140,481,941 - 140,561,948 (+)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

RAB38
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	88,982,414 - 89,051,335 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	90,026,601 - 90,092,945 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	83,121,858 - 83,183,698 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	86,710,358 - 86,772,796 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	86,710,358 - 86,773,142 (-)	Ensembl	panpan1.1		panPan2

RAB38
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	11,769,924 - 11,823,546 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	11,769,351 - 11,822,815 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	11,629,645 - 11,685,137 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	11,951,012 - 12,006,559 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	11,950,427 - 12,014,114 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	11,739,658 - 11,795,116 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	11,810,618 - 11,866,135 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	11,864,785 - 11,920,329 (+)	NCBI		UU_Cfam_GSD_1.0

Rab38
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	73,981,078 - 74,037,967 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936736	1,304,185 - 1,361,221 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936736	1,304,290 - 1,360,412 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAB38
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	21,577,033 - 21,640,115 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	21,577,083 - 21,640,637 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	23,798,471 - 23,863,103 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAB38
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	79,256,996 - 79,316,967 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	79,256,835 - 79,316,789 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	46,404,298 - 46,464,013 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rab38
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624845	1,906,671 - 1,984,029 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624845	1,908,410 - 1,983,897 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005379731	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01014888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01014889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01095846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000019178 ⟹ ENSCLAP00000018993

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955414	5,158,261 - 5,215,698 (+)	Ensembl

RefSeq Acc Id:

XM_005379731 ⟹ XP_005379788

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955414	5,158,860 - 5,214,108 (+)	NCBI

Sequence:

show sequence

GAAATCTCTGGCAGCTGTGCAGCGCGGCACAAGCAAGCGAACTCCGGAGGCCCTTCGCTTCCCG
TCCCGAGCGCAGCTCCTGTCTCCACCCACCTCCAAACCCGCGAAGTAGGAAGGAGGATTAACAG
GGGAGGAGTTCCGCCGAGTGGCCGCAGACGCTCTCCCAGCGCCCCACTCGCGCCCAGCGTCCGC
CCGCGCCGTGCCCAGGCTGCGCTTCCCGGCCACGCTCTCGGGGGCCGGCAGGATGCAGGCCCCG
CACAAGGAGCACCTGTACAAGCTGCTGGTGATCGGCGACCTGGGCGTGGGTAAGACCAGCATCA
TTAAGCGCTACGTGCACCAGAACTTCTCCTCGCATTACCGGGCCACCATCGGCGTGGACTTCGC
GCTCAAGGTGCTGCACTGGGACCCCGAGACCGTGGTGCGCCTGCAGCTCTGGGACATCGCAGGT
CAAGAAAGATTTGGAAACATGACAAGGGTCTATTACCGAGAAGCTATGGGTGCGTTCATTGTCT
TCGATGTCACCAGGCCAGCCACATTTGAAGCAGTGGCAAAGTGGAAAAATGATTTGGACTCAAA
GTTAACTCTCCCAAATGGCAAACCTGTTTCAGTGGTTTTACTAGCTAACAAATGTGACCAGGGG
AAGGATGTGCTCATGAACAATGGCCTCAAGATGGACCAGTTCTGCAAGGAGCATGGTTTCGTAG
GATGGTTTGAAACATCAGCAAAGGAAAATATAAACATCGATGAAGCCTCCAGATGCCTGGTGAA
GCACATACTTGCAAATGAGTGTGACCTAATGGAGTCTATAGAGCCGGACATCGTGAAGCCCCAT
CTCGCGTCACCTAAGGTCGTCAGCTGCTCCAGCTGTGCCAAATCCTAGTGGGCTCCTCGGCTGG
CATGTGACAGAAATAAGCCCAGGGCCCCATGAATTGTGCCTGAGTTTTTACCATTTTGGGTAAA
CATCAGATTAGGAAAACATGGCAAACCAAATATCTCCGCCTCAAGTTTTCCTGTAAGAGAGAAA
TAGCAAATGTTCTTTTTGTGTTTTTCACACCATCGGCACAGTTTTTACAAGCTCTTTTAATACA
TAGTTTGTTACAAAATTCTGTTGTATTGCAGAGCAAACTTTTGCAGGGCTGGAGGGGACCCTGG
TATTTGCTCCTTTAAATCAGCAAAGGCCTTAGGACTTAGAGAGAAGTGGGACAGAGCAAACCAG
CTGTCAAGTTAAGCACTGATATTTGCCTTGTCCTGGTGTGTCTTTGTTCAGATTTCAATACATT
CTCTGCAGCCTGACAGGTCTGTTAAATAGAAATAGTATTTTCCCCAGAGATGACCTCCATTCTC
GACAGACCCAAGAGCTGTCTGTGATTTGGCTCTTCAGAGTCGTGCACACAGGCTTCCTGTGCTT
TCGTTGCCTTCACTGTCACTTGCCAGGCCATGAATGCTGGTTTCCCTGAACACAGCATGAAAAG
AGCTGCCCCCTGTATGTGCCTTTTTTGTTAGCTTTCTCTGAACCAAGCTGTGGGACTCTTCTCT
ACATGTAATATATATTATATATATTTTCACAAGTGAAAAATAAAACATGAAAAGATGCTGTTTC
CCTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005379788	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000018993
	ENSCLAP00000018993.1

RefSeq Acc Id:

XP_005379788 ⟸ XM_005379731

- UniProtKB:

A0A8C2VSG6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQAPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLW
DIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVSVVLLANK
CDQGKDVLMNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHILANECDLMESIEPDI
VKPHLASPKVVSCSSCAKS

hide sequence

RefSeq Acc Id:

ENSCLAP00000018993 ⟸ ENSCLAT00000019178

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000013006	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000019178	ENTREZGENE
	ENSCLAT00000019178.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Rab29/Rab38/Rab32	UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/TrEMBL
	Small_GTPase	UniProtKB/TrEMBL
NCBI Gene	Rab38	ENTREZGENE
PANTHER	RAB FAMILY	UniProtKB/TrEMBL
	RAS-RELATED PROTEIN RAB	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
SMART	RAB	UniProtKB/TrEMBL
	RAN	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8C2VSG6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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