Rpp38 (ribonuclease P/MRP subunit p38)

Gene: Rpp38 (ribonuclease P/MRP subunit p38) Chinchilla lanigera

Analyze

Symbol:

Rpp38

Name:

ribonuclease P/MRP subunit p38

RGD ID:

8752812

Description:

ENCODES a protein that exhibits ribonuclease P activity (ortholog); ribonuclease P RNA binding (ortholog); INVOLVED IN tRNA 5'-leader removal (ortholog); PARTICIPATES IN tRNA maturation pathway; ASSOCIATED WITH hypoparathyroidism-deafness-renal disease syndrome (ortholog); melanoma (ortholog); FOUND IN fibrillar center (ortholog); multimeric ribonuclease P complex (ortholog); nucleolus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ribonuclease P protein subunit p38; ribonuclease P/MRP 38kDa subunit

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955429	19,358,765 - 19,360,973 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955429	19,358,765 - 19,360,973 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hypoparathyroidism-deafness-renal disease syndrome (ISO)

melanoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

tRNA 5'-leader removal (ISO)

Cellular Component

fibrillar center (ISO)

multimeric ribonuclease P complex (ISO)

nucleolus (ISO)

Molecular Function

protein binding (ISO)

ribonuclease P activity (ISO)

ribonuclease P RNA binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

tRNA maturation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Rpp38
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955429	19,358,765 - 19,360,973 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955429	19,358,765 - 19,360,973 (-)	NCBI	ChiLan1.0	ChiLan1.0

RPP38
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	15,097,355 - 15,104,257 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	15,097,180 - 15,139,818 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	15,139,354 - 15,146,256 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	15,179,188 - 15,186,262 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	10	15,067,814 - 15,074,888 (+)	NCBI		Celera
Cytogenetic Map	10	p13	NCBI
HuRef	10	15,049,413 - 15,056,395 (+)	NCBI		HuRef
CHM1_1	10	15,139,292 - 15,146,368 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	15,111,088 - 15,118,231 (+)	NCBI		T2T-CHM13v2.0

Rpp38
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	3,328,305 - 3,334,023 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	3,329,986 - 3,333,680 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	3,326,548 - 3,332,986 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	3,328,949 - 3,332,643 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	3,246,221 - 3,249,900 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	3,246,221 - 3,249,863 (-)	NCBI		MGSCv36	mm8
Celera	2	3,280,688 - 3,284,367 (-)	NCBI		Celera
Cytogenetic Map	2	A1	NCBI
cM Map	2	1.87	NCBI

Rpp38
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	79,823,237 - 79,826,908 (+)	NCBI		GRCr8
mRatBN7.2	17	74,914,066 - 74,917,742 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	74,908,932 - 74,927,431 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	78,380,911 - 78,384,455 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	82,216,290 - 82,219,834 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	76,264,235 - 76,267,779 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	78,915,450 - 78,919,144 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	78,915,604 - 78,919,143 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	80,556,274 - 80,560,521 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	86,033,450 - 86,036,990 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	86,046,905 - 86,047,736 (+)	NCBI
Celera	17	74,293,601 - 74,297,141 (+)	NCBI		Celera
Cytogenetic Map	17	q12.3	NCBI

RPP38
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	27,937,238 - 27,944,415 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	27,942,564 - 27,949,741 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	15,413,026 - 15,420,170 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	15,694,410 - 15,701,569 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	15,700,027 - 15,703,046 (+)	Ensembl	panpan1.1		panPan2

RPP38
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	21,612,114 - 21,617,371 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	21,612,200 - 21,614,485 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	18,725,394 - 18,730,634 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	21,913,363 - 21,918,600 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	21,913,380 - 21,918,563 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	19,113,947 - 19,119,188 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	19,948,839 - 19,954,079 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	20,575,433 - 20,580,672 (-)	NCBI		UU_Cfam_GSD_1.0

Rpp38
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	16,149,771 - 16,153,543 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936574	5,651,758 - 5,657,119 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936574	5,648,696 - 5,653,030 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RPP38
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	46,717,197 - 46,725,920 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	46,720,135 - 46,725,962 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	51,454,233 - 51,459,147 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RPP38
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	15,073,265 - 15,080,322 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	15,079,383 - 15,080,231 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666051	20,617,027 - 20,624,053 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rpp38
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624805	453,703 - 460,430 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624805	456,432 - 460,906 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005387145	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01028948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCE01098131	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01139986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000014938 ⟹ ENSCLAP00000014779

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955429	19,358,765 - 19,360,973 (-)	Ensembl

RefSeq Acc Id:

XM_005387145 ⟹ XP_005387202

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955429	19,358,765 - 19,360,973 (-)	NCBI

Sequence:

show sequence

CACGAGCAGCGGGAGTCGCCGCGGTGAGTGCGGGCGGCGCTCTGTCGGGCGGCGGGGCTTCGCG
CGGGGTGCGGGGAGGGGAGTCCGCGGGCGCGCGGTGTCCGCGGCTCCCGGGAACGTCTGGCGTG
GCTGGAGTAGCGGCCGTCGCGGCGCCCCCGGGCCCGCCGCAGCCCCTTCCGTGCGCTCCGTCTG
CTCGGCCCGGGCCTCGGCGCTCCCGTGCAGCGTGTGTCCGCGCGGCCGCCTCCTTCGGATATTC
GCCTCGCCTCCCGCCGGGGGCGGCTTCAGGCGGCGCCCATCCGGGTCCCCCGCGCCTGCGCCGG
CCGCGCCGAGCTGCGTTGCCCGCGCGCCGGGCCCCCCGCGCTCCCCGGCTTCGGCGAGCGTCCT
CGGGAGTCAGCCCGGCCTCGCGCTCTGCGGGTTTCCTGAGCGTCCTGCCCCAGCTTGACGCTGG
TGCGCGCCGCCTTGCTGTGCTGCTTATTAGACCGACAATCTTTCCTAAACTCCAAGCTGACGCC
AGGGACAGTGTTAGCGTTTTTCCTGTGTTATGGACAGCGCGTCCTGGGTAACCCATTGTGCGGA
AGAAAGAGCTGGAGATCAAACACAGGGCCTTGCCCTGCTATGCACGCCCCAAATTACTTAAATC
TTAAAAGAGGTCAAACGTCTGGTCACGTGACAGAGTCTCTGTAATTAGGTTTGCTGTAGCTTGT
CACGAATCTGAGAGACTACACTGCCTTTCTGGCTAACAAGAATTTTCCATTGTCATTTTGATTC
TCTGAAGGGTTTTCAAAATGGCTGCTGCCCCTCAAGCACCAGGAAGGGGTTCTGTTCGTAAGAC
CAGGCCTCTGACTGTGAAGACATCATTGAACAACCCATATGTTCTCTGCTGGAGCACCCTGGAC
AGAGAGGACATGCAGTTCATATTACAGACACTTGAGGACAGGTTCAAATCTATTGGACTTCAGA
AAATAGAGGATAAAAAGAAAAGGAAAAGGCCACCTCTTGTAAACAATCAAGGCAGAGAAAAATG
CGGCCTAGATGCTGGTGTGACTGAGGACCCCAAGGAGAAAAAGCCCGACGCTGACCAGCGGGCA
TCGGGGTGGACACCTGTGCATGTCAGGAAGCAGCTTGCCCTTGGCGTGAACGAGGTCACCCGGG
CCCTGGAGAGAAACGAGCTGCTCTTGGTGCTTGTGTGCAAGTCAGTCAAGCCCGCTGTCATCAC
CTCACACTTGATCCAGTTAAGTCTAAGCAGATCTGTTCCTGCCTGTCAGGTCCCCCGCCTCAGC
GAGAGAATTGCCCCCGTCATTGGCTTAAAATGTGTGCTAGCCTTGGGGTTCAGAAAGGGCACCT
CCGACTTTGCAGATGAAGTAAGAGCCATCATTCCCCGAGTGCCCAGCTTAAATGTACCATGGCT
TCAAGACAGAATTGAAAGTTCTGGAGAAAATGCAGAGACTGAATCTTTGGAAGACCAAGACAAA
GAGATCTTGGAAACTTCATTTGAAGACCTCTCAAAACATAAGAGAAAAATTGTGGAAGGGAGGC
TGGGTTCTGCTATAGCGTTACAACCACTTAAAATAAAGAAACTGATTCCCAACCCTAATAAGAT
AAGGAAACCACCTAAAAATAAAAAAACTATTTCAAAGTAATCTTGGAGAAAGCTGTCATTTTAA
TGCAATTTATAAAAAGACACGATGGGGGCTGGGGATTTAGCTCAGCAGCACAAGCGTGAGGTTG
TGAGTTCAATTCCCAGTACCAGAGGGGAAAAAAAACCTAAAAAAAAAGGACACAATGTAAAGAA
GCCTTAAAGTAAGCTACATTTACATATATTGTTGGGACCCTGTGGCAGTG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005387202	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000014779
	ENSCLAP00000014779.1

RefSeq Acc Id:

XP_005387202 ⟸ XM_005387145

- UniProtKB:

A0A8C2VLZ2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAAPQAPGRGSVRKTRPLTVKTSLNNPYVLCWSTLDREDMQFILQTLEDRFKSIGLQKIEDKK
KRKRPPLVNNQGREKCGLDAGVTEDPKEKKPDADQRASGWTPVHVRKQLALGVNEVTRALERNE
LLLVLVCKSVKPAVITSHLIQLSLSRSVPACQVPRLSERIAPVIGLKCVLALGFRKGTSDFADE
VRAIIPRVPSLNVPWLQDRIESSGENAETESLEDQDKEILETSFEDLSKHKRKIVEGRLGSAIA
LQPLKIKKLIPNPNKIRKPPKNKKTISK

hide sequence

RefSeq Acc Id:

ENSCLAP00000014779 ⟸ ENSCLAT00000014938

Protein Domains

Ribosomal protein eL8/eL30/eS12/Gadd45

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000010194	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000014938	ENTREZGENE
	ENSCLAT00000014938.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.1330.30	UniProtKB/TrEMBL
InterPro	L30e-like	UniProtKB/TrEMBL
	Ribosomal_L7Ae/L30e/S12e/Gad45	UniProtKB/TrEMBL
	Rpp38	UniProtKB/TrEMBL
NCBI Gene	Rpp38	ENTREZGENE
PANTHER	PTHR46948	UniProtKB/TrEMBL
	RIBONUCLEASE P PROTEIN SUBUNIT P38	UniProtKB/TrEMBL
Pfam	Ribosomal_L7Ae	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55315	UniProtKB/TrEMBL
UniProt	A0A8C2VLZ2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Rpp38	ribonuclease P/MRP subunit p38		ribonuclease P/MRP 38kDa subunit	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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