Stam (signal transducing adaptor molecule) - Rat Genome Database

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Gene: Stam (signal transducing adaptor molecule) Chinchilla lanigera
Analyze
Symbol: Stam
Name: signal transducing adaptor molecule
RGD ID: 8733261
Description: ENCODES a protein that exhibits ubiquitin-like protein ligase binding (ortholog); INVOLVED IN positive regulation of exosomal secretion (ortholog); regulation of extracellular exosome assembly (ortholog); PARTICIPATES IN interleukin-2 signaling pathway; ASSOCIATED WITH hypoparathyroidism-deafness-renal disease syndrome (ortholog); Imerslund-Grasbeck Syndrome (ortholog); FOUND IN cytosol (ortholog); ESCRT-0 complex (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: signal transducing adapter molecule 1; signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542910,306,957 - 10,366,081 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542910,306,957 - 10,366,072 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Stam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542910,306,957 - 10,366,081 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542910,306,957 - 10,366,072 (-)NCBIChiLan1.0ChiLan1.0
STAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381017,644,151 - 17,716,824 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1017,644,151 - 17,716,824 (+)EnsemblGRCh38hg38GRCh38
GRCh371017,686,150 - 17,758,823 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361017,726,130 - 17,797,913 (+)NCBINCBI36Build 36hg18NCBI36
Build 341017,726,129 - 17,797,913NCBI
Celera1017,619,602 - 17,691,384 (+)NCBICelera
Cytogenetic Map10p12.33NCBI
HuRef1017,598,859 - 17,671,557 (+)NCBIHuRef
CHM1_11017,686,508 - 17,759,210 (+)NCBICHM1_1
T2T-CHM13v2.01017,662,652 - 17,736,129 (+)NCBIT2T-CHM13v2.0
Stam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39214,078,912 - 14,152,351 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl214,078,909 - 14,154,445 (+)EnsemblGRCm39 Ensembl
GRCm38214,073,962 - 14,148,338 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl214,074,098 - 14,149,634 (+)EnsemblGRCm38mm10GRCm38
MGSCv37213,995,739 - 14,069,965 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36213,991,866 - 14,066,092 (+)NCBIMGSCv36mm8
Celera213,978,783 - 14,051,519 (+)NCBICelera
Cytogenetic Map2A2NCBI
cM Map210.36NCBI
Stam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81782,028,779 - 82,074,717 (+)NCBIGRCr8
mRatBN7.21777,120,235 - 77,166,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1777,120,158 - 77,166,467 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1780,570,551 - 80,615,048 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01784,405,965 - 84,450,462 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01778,453,865 - 78,498,362 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01781,209,795 - 81,256,111 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1781,209,867 - 81,255,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01782,954,327 - 83,002,657 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41788,276,082 - 88,321,955 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1776,453,145 - 76,499,077 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
STAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2830,485,153 - 30,561,119 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11030,492,656 - 30,566,440 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01017,962,759 - 18,035,654 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11018,232,548 - 18,305,169 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1018,232,548 - 18,305,197 (+)Ensemblpanpan1.1panPan2
STAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1219,264,392 - 19,344,187 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl219,266,055 - 19,344,045 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha216,365,991 - 16,445,808 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0219,553,884 - 19,634,156 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl219,553,652 - 19,652,382 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1216,756,688 - 16,836,708 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0217,592,245 - 17,672,295 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0218,212,306 - 18,292,067 (-)NCBIUU_Cfam_GSD_1.0
Stam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934418,270,841 - 18,333,310 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365209,624,628 - 9,689,686 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365209,627,674 - 9,689,658 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1043,947,011 - 44,016,056 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11043,946,990 - 44,016,064 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21048,632,911 - 48,699,716 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1917,590,252 - 17,662,278 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl917,590,268 - 17,663,986 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605123,235,162 - 23,320,904 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479610,201,518 - 10,269,311 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479610,195,897 - 10,269,311 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000006669   ⟹   ENSCLAP00000006561
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542910,306,957 - 10,366,081 (-)Ensembl
RefSeq Acc Id: XM_005386961   ⟹   XP_005387018
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542910,306,957 - 10,366,072 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005387018 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000006561
  ENSCLAP00000006561.1
Reference Protein Sequences
RefSeq Acc Id: XP_005387018   ⟸   XM_005386961
- UniProtKB: A0A8C2UWR8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000006561   ⟸   ENSCLAT00000006669
Protein Domains
SH3   VHS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004624 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006669 ENTREZGENE
  ENSCLAT00000006669.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1940 UniProtKB/TrEMBL
  1.25.40.90 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro ENTH_VHS UniProtKB/TrEMBL
  GAT_STAM1 UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  STAM1_SH3 UniProtKB/TrEMBL
  UIM_dom UniProtKB/TrEMBL
  VHS_dom UniProtKB/TrEMBL
  VHS_STAM1 UniProtKB/TrEMBL
NCBI Gene Stam ENTREZGENE
PANTHER JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE UniProtKB/TrEMBL
  SIGNAL TRANSDUCING ADAPTER MOLECULE 1 UniProtKB/TrEMBL
Pfam SH3_1 UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
  VHS UniProtKB/TrEMBL
PRINTS P67PHOX UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
  VHS UniProtKB/TrEMBL
SMART SH3 UniProtKB/TrEMBL
  VHS UniProtKB/TrEMBL
Superfamily-SCOP SSF48464 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A8C2UWR8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Stam  signal transducing adaptor molecule    signal transducing adaptor molecule (SH3 domain and ITAM motif) 1  Symbol and/or name change 5135510 APPROVED