Hspb7 (heat shock protein family B (small) member 7)

Gene: Hspb7 (heat shock protein family B (small) member 7) Chinchilla lanigera

Analyze

Symbol:

Hspb7

Name:

heat shock protein family B (small) member 7

RGD ID:

8728094

Description:

ENCODES a protein that exhibits filamin binding (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); Moebius syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); aggresome (ortholog); cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

heat shock 27kDa protein family, member 7 (cardiovascular); heat shock protein beta-7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955527	2,219,462 - 2,222,824 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955527	2,219,462 - 2,222,824 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 1p36 deletion syndrome (ISO)

Moebius syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

actin cytoskeleton (ISO)

aggresome (ISO)

cytoplasm (ISO)

nucleoplasm (ISO)

nucleus (ISO)

Molecular Function

filamin binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Hspb7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955527	2,219,462 - 2,222,824 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955527	2,219,462 - 2,222,824 (+)	NCBI	ChiLan1.0	ChiLan1.0

HSPB7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	16,014,029 - 16,019,594 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	16,014,028 - 16,019,594 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	16,340,524 - 16,346,089 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	16,213,111 - 16,217,538 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	16,085,830 - 16,090,257	NCBI
Celera	1	14,820,429 - 14,825,190 (-)	NCBI		Celera
Cytogenetic Map	1	p36.13	NCBI
HuRef	1	14,859,583 - 14,864,344 (-)	NCBI		HuRef
CHM1_1	1	16,139,026 - 16,143,787 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	15,455,340 - 15,460,905 (-)	NCBI		T2T-CHM13v2.0

Hspb7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	141,148,090 - 141,152,621 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	141,148,090 - 141,152,622 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	141,420,779 - 141,425,310 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	141,420,779 - 141,425,311 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	140,976,694 - 140,981,225 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	140,692,855 - 140,697,386 (+)	NCBI		MGSCv36	mm8
Celera	4	143,237,268 - 143,241,799 (+)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	74.08	NCBI

Hspb7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	159,010,759 - 159,014,245 (+)	NCBI		GRCr8
mRatBN7.2	5	153,727,782 - 153,731,268 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	153,727,588 - 153,731,266 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	156,414,594 - 156,418,080 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	158,187,880 - 158,191,366 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	158,177,061 - 158,180,547 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	159,968,077 - 159,971,563 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	159,967,839 - 159,971,562 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	163,688,616 - 163,692,102 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	160,311,908 - 160,315,394 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	160,322,230 - 160,322,989 (+)	NCBI
Celera	5	152,089,504 - 152,092,990 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

HSPB7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	210,902,785 - 210,906,988 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	210,151,188 - 210,155,577 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	15,151,471 - 15,156,234 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	16,144,200 - 16,148,959 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

HSPB7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	81,628,051 - 81,631,939 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	81,619,999 - 81,630,483 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	78,163,485 - 78,167,372 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	82,273,705 - 82,277,606 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	82,273,504 - 82,277,580 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	79,026,872 - 79,030,773 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	80,044,020 - 80,047,921 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	81,111,730 - 81,115,632 (+)	NCBI		UU_Cfam_GSD_1.0

Hspb7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	37,759,259 - 37,762,650 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	3,583,509 - 3,587,508 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	3,583,999 - 3,587,316 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HSPB7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	75,166,992 - 75,175,013 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	75,171,507 - 75,174,918 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

HSPB7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	116,280,155 - 116,284,982 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	116,280,704 - 116,285,133 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	19,806,487 - 19,811,415 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hspb7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	2,193,778 - 2,197,707 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	2,194,420 - 2,197,713 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005409852	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01069425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCB01004969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000008649 ⟹ ENSCLAP00000008522

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955527	2,219,462 - 2,222,824 (+)	Ensembl

RefSeq Acc Id:

XM_005409852 ⟹ XP_005409909

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955527	2,219,462 - 2,222,824 (+)	NCBI

Sequence:

show sequence

TCGGGGCCCAGCACGCTCCGCCGGAGCCCCGCACCCACGCCTTCTCCTGTTCCGCCTCTGCCCG
CTCAGGGCCCAGCGCTGCCTGTGGATGAGCCACCGGACCTCCTCCTCCTTCAGAGCGGAGAGAA
GCTTCCACTCCTCCTCCTCCTCCTCCTCCTCCTCCTCCTCCTCCTCTGCGGCCTCCCATGCCCT
CCCGCCCCAGGACCCACCCATGGAGAAGGCCCTGAGCTTGTTTTCCGAGGACTTTGGCAGCTTC
ATGAGGCCCCACTCGGAGCCCCTGGCCTTCCCAGCCCGCCCCGCAGGACCAGGCAACATCAAGA
CCCTTGGAGACGCCTACGAGTTTGCAGTGGACGTCAGAGACTTCTCCCCTGAGGACATCATCGT
CACCACCTCCAACAACCACATCGAGGTTCGGGCAGAGAAGCTGGCGGCGGACGGCACTGTCATG
AACACCTTCGCTCACAAGTGCCAGCTGCCGGAGGACGTGGACCCAACCTCGGTGACCTCAGCCC
TGCGGGAGGACGGCAGCCTCACCATCCGGGCTCGGCGTCACCCGCACACGGAGCACGTCCAGCA
GACCTTCCGGACCGAGATCAAAATCTGAGGCCCGCAACCACTGCCCTGCCTGCTCTCCCTCCTC
CCCGAGGGGCCTCCCTAGAGCCTACCGAGTCCCGGACGACGCCCCCCCCAGGACAGCTCAGCTC
AGCTCCTGGAGCCCCTAGGCCCCAGGCGGGCATCGCCCCCAAACTAGGGCCCTCCACTCTACCA
AGGGCAGCCGGCAACCCCCGTATCTCCGTGTGGCCCCGAGATTCCAGAGAAGGTATCTCTCAAT
TAGGAATTGAGGGGCTGGGTAGGGACAGCTAGGTCCTAAAGACCCACTTTGAGGAAGGGGGAGG
GGACAGGCAGGGCCTCTGGACAAAAGATCTGCAGGACAGACAGACAGGGGAGCCAAAAGCGGGG
GGGCGAGGGGGGCGCGCTGGACCAGTGGTTCCCTGGCAAAGCAGAGCAGCTCAGGCTGAGGGAA
GGTCACGGGCAAAGTGCCCATCCAGGTGAGACTGCCGGAGGGCCTGGGAGGCCACAGCGTGATG
ACACCTCCCCTGGCCACCCCCTGCAACCCAGCCCGCCAGCTGTGCCCGGACAGGGCACGTCCGT
CTGCACAGATGGGATTTTTCCAATACAGCTGGTTCGTGACAAACCGGGTGAAATCCTGCTGTCC
CCTACCTGCCTGGTGCCTGCAGGTGTGTGGGACTTGTCCTCCCCCACCGCAGACCTGGGCTCCC
GGGTCGCTCCCCCTGCAGCCAGGGTCCCCTACAGTGACCGTCTCCTGCAATCGCCCCACCCCTC
AGGTGCACCCACCCTTCCCGCCCTCCACCCATCCGCACATCTGGGGGCTTCGTGTGGAACCCAC
ACCCCAGGCCCATTGTCCTTCACATCCTCAGTGAGGCCAAATCAAAGCACCCTAAAAGTGGACT
CCGCCCCTCCATTTTTATCCATGGGGAAACTTGAGTGTCTAGCAAGCCCTTGGCACTGGCCTTT
GTCACTGGAGGGTAGATGCGAGCCCAGGATGTCCGTGGTCCTCAGCCCCAACTCTGAGGCCAAG
GGGAGTCCCCTCACTCTGTCCCCCTGGGGCTCTGCGTCCTGCTGGGGTGGAGGGGTCACAGAGA
GAGCCCTGAGACCCGTTCCCTCCTGGTCCCCGATCCGTGAGTGTGGCTCAGGCTTCCAAAGCGG
GGGGGAGGGGAGAGGGTGGTTCACAGTCAGTGAGGGGCTCAGGAAAGAGGTGGGGCCACCTGTG
CCACTGCTTCTTGGCTAAGCTCAGGGTCAGGGGCTTCTGACCCCTCTCACTCTGGGGCGCTTGG
GGAGGGCAGGTGGGGCAGCAGGAGAGTGGGCGCTGTAACCTGGACGCACAATAAATGACAGTGT
CACGGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005409909	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000008522
	ENSCLAP00000008522.1

RefSeq Acc Id:	XP_005409909 ⟸ XM_005409852
- UniProtKB:	A0A8C2V1E0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSHRTSSSFRAERSFHSSSSSSSSSSSSSAASHALPPQDPPMEKALSLFSEDFGSFMRPHSEPL AFPARPAGPGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQ LPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI hide sequence

RefSeq Acc Id:

ENSCLAP00000008522 ⟸ ENSCLAT00000008649

Protein Domains

sHSP

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000005960	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000008649	ENTREZGENE
	ENSCLAT00000008649.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.790	UniProtKB/TrEMBL
InterPro	A-crystallin/Hsp20_dom	UniProtKB/TrEMBL
	ACD_HspB7	UniProtKB/TrEMBL
	Alpha-crystallin/sHSP_animal	UniProtKB/TrEMBL
	HSP20-like_chaperone	UniProtKB/TrEMBL
NCBI Gene	Hspb7	ENTREZGENE
PANTHER	HEAT SHOCK PROTEIN BETA-7	UniProtKB/TrEMBL
	HEAT SHOCK PROTEIN BETA-7-RELATED	UniProtKB/TrEMBL
Pfam	HSP20	UniProtKB/TrEMBL
PRINTS	ACRYSTALLIN	UniProtKB/TrEMBL
PROSITE	SHSP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49764	UniProtKB/TrEMBL
UniProt	A0A8C2V1E0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Hspb7	heat shock protein family B (small) member 7		heat shock 27kDa protein family, member 7 (cardiovascular)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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