Unc45b (unc-45 myosin chaperone B) - Rat Genome Database

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Gene: Unc45b (unc-45 myosin chaperone B) Chinchilla lanigera
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Symbol: Unc45b
Name: unc-45 myosin chaperone B
RGD ID: 8719296
Description: ENCODES a protein that exhibits Hsp90 protein binding (ortholog); INVOLVED IN chaperone-mediated protein folding (ortholog); ASSOCIATED WITH cataract 43 (ortholog); Craniofacial Abnormalities (ortholog); dilated cardiomyopathy 1A (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: unc-45 homolog B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554819,833,905 - 9,860,697 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554819,833,918 - 9,860,202 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Unc45b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554819,833,905 - 9,860,697 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554819,833,918 - 9,860,202 (+)NCBIChiLan1.0ChiLan1.0
UNC45B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381735,147,817 - 35,189,345 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1735,147,817 - 35,189,345 (+)EnsemblGRCh38hg38GRCh38
GRCh371733,474,836 - 33,516,364 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361730,498,949 - 30,540,477 (+)NCBINCBI36Build 36hg18NCBI36
Build 341730,499,395 - 30,537,691NCBI
Celera1730,385,024 - 30,426,539 (+)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1729,659,471 - 29,700,988 (+)NCBIHuRef
CHM1_11733,539,195 - 33,580,717 (+)NCBICHM1_1
T2T-CHM13v2.01736,095,726 - 36,137,280 (+)NCBIT2T-CHM13v2.0
Unc45b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391182,802,112 - 82,834,284 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1182,801,376 - 82,834,229 (+)EnsemblGRCm39 Ensembl
GRCm381182,911,253 - 82,943,406 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,910,550 - 82,943,403 (+)EnsemblGRCm38mm10GRCm38
MGSCv371182,724,755 - 82,756,908 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361182,727,524 - 82,759,601 (+)NCBIMGSCv36mm8
Celera1192,535,272 - 92,566,088 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1150.3NCBI
Unc45b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81068,343,011 - 68,370,683 (+)NCBIGRCr8
mRatBN7.21067,845,464 - 67,873,143 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1067,845,462 - 67,873,389 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1072,465,507 - 72,493,429 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01071,970,884 - 71,998,806 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01067,434,975 - 67,462,832 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01070,262,340 - 70,290,445 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1070,262,361 - 70,290,445 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01069,893,499 - 69,920,936 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,128,525 - 71,156,471 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11071,142,158 - 71,170,095 (+)NCBI
Celera1066,789,697 - 66,817,760 (+)NCBICelera
Cytogenetic Map10q26NCBI
UNC45B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21929,276,717 - 29,318,181 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11731,157,541 - 31,199,152 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01721,596,445 - 21,638,487 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11721,888,426 - 21,930,357 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1721,888,426 - 21,930,357 (-)Ensemblpanpan1.1panPan2
UNC45B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1938,189,917 - 38,218,337 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl938,189,917 - 38,218,025 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha937,413,649 - 37,442,109 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0939,001,372 - 39,030,073 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl938,998,793 - 39,029,898 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1937,785,169 - 37,813,631 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0938,070,500 - 38,099,164 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0938,157,973 - 38,186,674 (-)NCBIUU_Cfam_GSD_1.0
Unc45b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560237,195,294 - 37,218,884 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493653873,176 - 96,712 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493653873,180 - 96,677 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC45B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,994,194 - 40,030,966 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11239,997,254 - 40,031,368 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,508,324 - 41,542,493 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UNC45B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11628,649,541 - 28,690,467 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660751,292,605 - 1,334,228 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc45b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248753,009,763 - 3,037,282 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248753,009,763 - 3,037,204 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000019473   ⟹   ENSCLAP00000019285
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554819,833,905 - 9,860,697 (+)Ensembl
RefSeq Acc Id: XM_005402873   ⟹   XP_005402930
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554819,833,918 - 9,860,202 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013503334   ⟹   XP_013358788
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554819,834,033 - 9,860,202 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005402930 (Get FASTA)   NCBI Sequence Viewer  
  XP_013358788 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000019285
  ENSCLAP00000019285.1
RefSeq Acc Id: XP_005402930   ⟸   XM_005402873
- UniProtKB: A0A8C2VW55 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013358788   ⟸   XM_013503334
- UniProtKB: A0A8C2VW55 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000019285   ⟸   ENSCLAT00000019473
Protein Domains
UNC-45/Cro1/She4 central


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013212 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019473 ENTREZGENE
  ENSCLAT00000019473.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  1.25.40.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
  UCS_central_dom UniProtKB/TrEMBL
NCBI Gene Unc45b ENTREZGENE
PANTHER FI21225P1 UniProtKB/TrEMBL
  PROTEIN UNC-45 HOMOLOG B UniProtKB/TrEMBL
Pfam UNC45-central UniProtKB/TrEMBL
PROSITE TPR UniProtKB/TrEMBL
SMART ARM UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
UniProt A0A8C2VW55 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Unc45b  unc-45 myosin chaperone B    unc-45 homolog B (C. elegans)  Symbol and/or name change 5135510 APPROVED