MIR6749 (microRNA 6749) - Rat Genome Database

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Pathways
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Gene: MIR6749 (microRNA 6749) Homo sapiens
Analyze
Symbol: MIR6749
Name: microRNA 6749
RGD ID: 8550079
HGNC Page HGNC:50087
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: hsa-mir-6749
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381164,902,387 - 64,902,455 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1164,902,387 - 64,902,455 (-)EnsemblGRCh38hg38GRCh38
GRCh371164,669,859 - 64,669,927 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map11q13.1NCBI
HuRef1160,996,890 - 60,996,958 (-)NCBIHuRef
CHM1_11164,553,641 - 64,553,709 (-)NCBICHM1_1
T2T-CHM13v2.01164,895,625 - 64,895,693 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:22955976  


Genomics

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:87448
Count of gene targets:23814
Count of transcripts:66461
Interacting mature miRNAs:hsa-miR-6749-3p, hsa-miR-6749-5p
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium
Low 33 63 36 10 66 8 100 14 43 5 41 36 2 28 48
Below cutoff 27 29 17 6 42 5 50 32 34 9 15 19 2 12 29 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000617008
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1164,902,387 - 64,902,455 (-)Ensembl
RefSeq Acc Id: NR_106807
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381164,902,387 - 64,902,455 (-)NCBI
HuRef1160,996,890 - 60,996,958 (-)NCBI
CHM1_11164,553,641 - 64,553,709 (-)NCBI
T2T-CHM13v2.01164,895,625 - 64,895,693 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC MIR6749 COSMIC
Ensembl Genes ENSG00000274314 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000617008 ENTREZGENE
GTEx ENSG00000274314 GTEx
HGNC ID HGNC:50087 ENTREZGENE
Human Proteome Map MIR6749 Human Proteome Map
miRBase MI0022594 ENTREZGENE
NCBI Gene MIR6749 ENTREZGENE
RNAcentral URS0000759E9A RNACentral
  URS000075B263 RNACentral
  URS000075E855 RNACentral