Xntrpc (Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthrough) - Rat Genome Database

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Gene: Xntrpc (Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthrough) Mus musculus
Analyze
Symbol: Xntrpc
Name: Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthrough
RGD ID: 8548938
MGI Page MGI
Description: This locus represents naturally occurring readthrough transcription between the neighboring Xndr (XRCC1 N-terminal domain-related) and Trpc2 (transient receptor potential cation channel, subfamily C, member 2) genes on chromosome 7. Readthrough transcripts include one that encodes a fusion protein that shares sequence identity with each individual gene product and one that is a candidate for nonsense-mediated mRNA decay (NMD), and thus is unlikely to produce a protein product. [provided by RefSeq, Nov 2013]
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Xndr-t; Xndr-trpc2; Xndr-Trpc2 readthrough
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397101,714,698 - 101,746,071 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7101,714,920 - 101,746,071 (+)EnsemblGRCm39 Ensembl
GRCm387102,065,491 - 102,096,864 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7102,065,713 - 102,096,864 (+)EnsemblGRCm38mm10GRCm38
Celera7102,440,643 - 102,463,923 (+)NCBICelera
Cytogenetic Map7E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)
ethanol  (EXP)
triptonide  (EXP)
tungsten  (EXP)

References
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:21854574   PMID:21873635  


Genomics

Variants

.
Variants in Xntrpc
745 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768365595102365702Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785365595112533819Mouse
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787143137119485380Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
27095929Pglq8_mpelvic girdle length QTL 8, 10 week (mouse)787849208108099207Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
13464255Ifvrq2_minfluenza virus resistance QTL 2 (mouse)792500698106455693Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000084843   ⟹   ENSMUSP00000081903
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7101,714,985 - 101,745,541 (+)Ensembl
GRCm38.p6 Ensembl7102,065,778 - 102,096,334 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123372   ⟹   ENSMUSP00000121068
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7101,714,920 - 101,746,071 (+)Ensembl
GRCm38.p6 Ensembl7102,065,713 - 102,096,864 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139104   ⟹   ENSMUSP00000122430
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7101,725,087 - 101,745,533 (+)Ensembl
GRCm38.p6 Ensembl7102,075,880 - 102,096,326 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155078   ⟹   ENSMUSP00000123466
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7101,725,083 - 101,745,541 (+)Ensembl
GRCm38.p6 Ensembl7102,075,876 - 102,096,334 (+)Ensembl
RefSeq Acc Id: NM_011644   ⟹   NP_035774
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397101,720,426 - 101,746,071 (+)NCBI
GRCm387102,071,219 - 102,096,864 (+)NCBI
Celera7102,440,643 - 102,463,923 (+)NCBI
Sequence:
RefSeq Acc Id: NR_104582
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397101,714,698 - 101,746,071 (+)NCBI
GRCm387102,065,491 - 102,096,864 (+)NCBI
Celera7102,440,643 - 102,463,923 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_035774 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000081903
  ENSMUSP00000081903.4
  ENSMUSP00000122430.2
  ENSMUSP00000123466.2
Reference Protein Sequences
RefSeq Acc Id: NP_035774   ⟸   NM_011644
- UniProtKB: Q9R244 (UniProtKB/Swiss-Prot),   Q9R243 (UniProtKB/Swiss-Prot),   Q9ES60 (UniProtKB/Swiss-Prot),   Q9ES59 (UniProtKB/Swiss-Prot),   F8VQM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000122430   ⟸   ENSMUST00000139104
RefSeq Acc Id: ENSMUSP00000081903   ⟸   ENSMUST00000084843
RefSeq Acc Id: ENSMUSP00000121068   ⟸   ENSMUST00000123372
RefSeq Acc Id: ENSMUSP00000123466   ⟸   ENSMUST00000155078
Protein Domains
DNA-repair protein Xrcc1 N-terminal   Transient receptor ion channel


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000070425 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000084843 ENTREZGENE
  ENSMUST00000084843.10 UniProtKB/TrEMBL
  ENSMUST00000139104.3 UniProtKB/TrEMBL
  ENSMUST00000155078.8 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
InterPro Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Galactose-bd-like UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  TRP_dom UniProtKB/TrEMBL
  TRPC2_channel UniProtKB/TrEMBL
  TRPC_channel UniProtKB/TrEMBL
  Xrcc1_N UniProtKB/TrEMBL
KEGG Report mmu:102443351 UniProtKB/TrEMBL
MGD MGI:5546370 ENTREZGENE
NCBI Gene Xntrpc ENTREZGENE
PANTHER DNA-REPAIR PROTEIN XRCC1 UniProtKB/TrEMBL
  PTHR10117 UniProtKB/TrEMBL
  PTHR10117:SF6 UniProtKB/TrEMBL
  XRCC1_N DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
  TRP_2 UniProtKB/TrEMBL
  XRCC1_N UniProtKB/TrEMBL
PhenoGen Xntrpc PhenoGen
PRINTS TRNSRECEPTRP UniProtKB/TrEMBL
  TRPCHANNEL2 UniProtKB/TrEMBL
SMART TRP_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
  SSF49785 UniProtKB/TrEMBL
UniProt F6WIA6_MOUSE UniProtKB/TrEMBL
  F7D6D1_MOUSE UniProtKB/TrEMBL
  F8VQM8 ENTREZGENE, UniProtKB/TrEMBL
  Q9ES59 ENTREZGENE
  Q9ES60 ENTREZGENE
  Q9R243 ENTREZGENE
  Q9R244 ENTREZGENE