C10orf95-AS1 (C10orf95 antisense RNA 1) - Rat Genome Database

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Gene: C10orf95-AS1 (C10orf95 antisense RNA 1) Homo sapiens
Analyze
Symbol: C10orf95-AS1
Name: C10orf95 antisense RNA 1
RGD ID: 8548341
HGNC Page HGNC:45238
Description: ASSOCIATED WITH desmoplastic/nodular medulloblastoma; INTERACTS WITH 2-hydroxypropanoic acid; acrylamide; aflatoxin B1
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: RPARP antisense RNA 1; RPARP-AS1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810102,449,817 - 102,456,293 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10102,449,816 - 102,461,106 (+)EnsemblGRCh38hg38GRCh38
GRCh3710104,209,574 - 104,216,050 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera1097,950,508 - 97,956,966 (+)NCBICelera
Cytogenetic Map10q24.32NCBI
HuRef1097,843,282 - 97,850,020 (+)NCBIHuRef
CHM1_110104,493,040 - 104,499,513 (+)NCBICHM1_1
T2T-CHM13v2.010103,334,804 - 103,341,280 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7566098   PMID:12477932   PMID:14702039   PMID:24133439   PMID:38308235  


Genomics

Variants

.
Variants in C10orf95-AS1
3 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q24.31-26.3(chr10:100600492-133622588)x3 copy number gain See cases [RCV000137747] Chr10:100600492..133622588 [GRCh38]
Chr10:102360249..135436092 [GRCh37]
Chr10:102350239..135286082 [NCBI36]
Chr10:10q24.31-26.3		 pathogenic
GRCh38/hg38 10q23.33-25.3(chr10:95112607-116776637)x3 copy number gain See cases [RCV000050747] Chr10:95112607..116776637 [GRCh38]
Chr10:96872364..118383651 [GRCh37]
Chr10:96862354..118526138 [NCBI36]
Chr10:10q23.33-25.3		 pathogenic
GRCh38/hg38 10q24.32-24.33(chr10:102243341-103929730)x1 copy number loss See cases [RCV000052568] Chr10:102243341..103929730 [GRCh38]
Chr10:104003098..105689488 [GRCh37]
Chr10:103993088..105679478 [NCBI36]
Chr10:10q24.32-24.33		 pathogenic
GRCh38/hg38 10q23.31-26.3(chr10:91048545-133620674)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|See cases [RCV000053560] Chr10:91048545..133620674 [GRCh38]
Chr10:92808302..135434178 [GRCh37]
Chr10:92798282..135284168 [NCBI36]
Chr10:10q23.31-26.3		 pathogenic
GRCh38/hg38 10q24.31-26.3(chr10:100194215-132432797)x3 copy number gain See cases [RCV000053564] Chr10:100194215..132432797 [GRCh38]
Chr10:101953972..134246301 [GRCh37]
Chr10:101943962..134096291 [NCBI36]
Chr10:10q24.31-26.3		 pathogenic
NM_001363580.1(C10orf95):c.507G>A (p.Gln169=) single nucleotide variant not specified [RCV004215629] Chr10:102450587 [GRCh38]
Chr10:104210344 [GRCh37]
Chr10:10q24.32		 uncertain significance
NM_001363580.1(C10orf95):c.440G>A (p.Arg147His) single nucleotide variant not specified [RCV004071568] Chr10:102450654 [GRCh38]
Chr10:104210411 [GRCh37]
Chr10:10q24.32		 uncertain significance
NM_001363580.1(C10orf95):c.410T>C (p.Leu137Pro) single nucleotide variant not specified [RCV004241380] Chr10:102450684 [GRCh38]
Chr10:104210441 [GRCh37]
Chr10:10q24.32		 uncertain significance
NC_000010.11:g.(102444036_?)_(?_104726221)del deletion Desmoplastic/nodular medulloblastoma [RCV000003754] Chr10:102444036..104726221 [GRCh38]
Chr10:10q24.32-25.1		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1474
Count of miRNA genes:689
Interacting mature miRNAs:780
Transcripts:ENST00000473970, ENST00000492465, ENST00000494270, ENST00000594818, ENST00000596045, ENST00000596366, ENST00000597488, ENST00000598368
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 580 91 1157 158 630 28 1289 59 2224 128 965 1254 133 57 741 2
Low 1853 2868 566 464 1311 436 3065 2117 1484 290 485 357 37 1147 2046 2
Below cutoff 1 25 1 7 1 17 3 4 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000473970
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,449,816 - 102,456,297 (+)Ensembl
RefSeq Acc Id: ENST00000492465
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,449,853 - 102,456,293 (+)Ensembl
RefSeq Acc Id: ENST00000494270
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,449,817 - 102,456,265 (+)Ensembl
RefSeq Acc Id: ENST00000594818
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,450,193 - 102,461,106 (+)Ensembl
RefSeq Acc Id: ENST00000596045
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,450,631 - 102,451,441 (+)Ensembl
RefSeq Acc Id: ENST00000596366
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,450,554 - 102,455,883 (+)Ensembl
RefSeq Acc Id: ENST00000597488
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,451,602 - 102,453,539 (+)Ensembl
RefSeq Acc Id: ENST00000598368
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,453,840 - 102,456,292 (+)Ensembl
RefSeq Acc Id: ENST00000657934
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,449,837 - 102,456,297 (+)Ensembl
RefSeq Acc Id: ENST00000659211
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,450,804 - 102,456,265 (+)Ensembl
RefSeq Acc Id: ENST00000663480
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,449,840 - 102,456,293 (+)Ensembl
RefSeq Acc Id: ENST00000669625
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,449,980 - 102,456,297 (+)Ensembl
RefSeq Acc Id: ENST00000670059
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10102,450,126 - 102,456,293 (+)Ensembl
RefSeq Acc Id: NR_038937
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810102,449,817 - 102,456,293 (+)NCBI
HuRef1097,843,282 - 97,850,020 (+)NCBI
CHM1_110104,493,040 - 104,499,513 (+)NCBI
T2T-CHM13v2.010103,334,804 - 103,341,280 (+)NCBI
Sequence:
RefSeq Acc Id: NR_038938
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810102,449,817 - 102,456,293 (+)NCBI
HuRef1097,843,282 - 97,850,020 (+)NCBI
CHM1_110104,493,040 - 104,499,513 (+)NCBI
T2T-CHM13v2.010103,334,804 - 103,341,280 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC C10orf95-AS1 COSMIC
Ensembl Genes ENSG00000269609 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000473970 ENTREZGENE
  ENST00000492465 ENTREZGENE
GTEx ENSG00000269609 GTEx
HGNC ID HGNC:45238 ENTREZGENE
Human Proteome Map C10orf95-AS1 Human Proteome Map
NCBI Gene RPARP-AS1 ENTREZGENE
RNAcentral URS000075B6B9 RNACentral
  URS000075DFC1 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-10-05 C10orf95-AS1  C10orf95 antisense RNA 1  RPARP-AS1  RPARP antisense RNA 1  Symbol and/or name change 19259463 PROVISIONAL