Rnf212b (ring finger protein 212B) - Rat Genome Database

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Gene: Rnf212b (ring finger protein 212B) Rattus norvegicus
Analyze
Symbol: Rnf212b
Name: ring finger protein 212B
RGD ID: 7500178
Description: Predicted to enable SUMO transferase activity and metal ion binding activity. Predicted to be involved in reciprocal meiotic recombination. Predicted to be located in synaptonemal complex. Orthologous to human RNF212B (ring finger protein 212B); INTERACTS WITH Aflatoxin B2 alpha (ortholog); benzo[a]pyrene (ortholog); benzo[e]pyrene (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC102550789; RING finger protein C14orf164 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,244,620 - 32,292,358 (+)NCBIGRCr8
mRatBN7.21528,274,629 - 28,321,093 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,244,083 - 28,321,347 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01533,430,269 - 33,509,698 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01537,318,544 - 37,396,548 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1527,822,288 - 27,900,302 (+)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Rnf212b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,244,620 - 32,292,358 (+)NCBIGRCr8
mRatBN7.21528,274,629 - 28,321,093 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,244,083 - 28,321,347 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01533,430,269 - 33,509,698 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01537,318,544 - 37,396,548 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1527,822,288 - 27,900,302 (+)NCBICelera
Cytogenetic Map15p13NCBI
RNF212B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,185,336 - 23,273,477 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,185,316 - 23,273,477 (+)EnsemblGRCh38hg38GRCh38
GRCh371423,654,545 - 23,742,686 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,724,385 - 22,809,408 (+)NCBINCBI36Build 36hg18NCBI36
Celera143,572,254 - 3,602,270 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,823,625 - 3,860,155 (+)NCBIHuRef
CHM1_11423,705,740 - 23,742,151 (+)NCBICHM1_1
T2T-CHM13v2.01417,386,004 - 17,474,456 (+)NCBIT2T-CHM13v2.0
Rnf212b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,020,798 - 55,091,567 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,051,598 - 55,091,565 (+)EnsemblGRCm39 Ensembl
GRCm381454,783,341 - 54,854,110 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,814,141 - 54,854,108 (+)EnsemblGRCm38mm10GRCm38
Celera1452,576,109 - 52,657,147 (+)NCBICelera
Cytogenetic Map14C2- C3NCBI
Rnf212b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540937,041,751 - 37,095,179 (-)NCBIChiLan1.0ChiLan1.0
RNF212B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,668,210 - 24,706,850 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,884,700 - 23,923,340 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,056,671 - 4,093,210 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11422,153,247 - 22,188,319 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1422,153,247 - 22,188,319 (+)Ensemblpanpan1.1panPan2
RNF212B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,509,481 - 3,552,600 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,509,638 - 3,544,740 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,457,882 - 3,500,161 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,617,537 - 3,659,814 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,617,689 - 3,652,792 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,308,549 - 3,351,225 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,369,825 - 3,412,538 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,632,387 - 3,674,674 (+)NCBIUU_Cfam_GSD_1.0
Rnf212b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,272,431 - 35,302,846 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,088,424 - 1,116,352 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,086,237 - 1,116,352 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF212B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,796,882 - 75,829,620 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,798,895 - 75,831,455 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,916,406 - 80,942,492 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF212B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,609,267 - 23,646,333 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,611,965 - 23,644,935 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605922,773,394 - 22,861,081 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf212b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248209,268,727 - 9,322,963 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf212b
175 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000115058   ⟹   ENSRNOP00000092948
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1528,244,083 - 28,321,347 (+)Ensembl
RefSeq Acc Id: XM_017599876   ⟹   XP_017455365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81532,244,620 - 32,292,358 (+)NCBI
mRatBN7.21528,274,629 - 28,321,093 (+)NCBI
Rnor_6.01533,460,789 - 33,509,698 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_017455365 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000092948
  ENSRNOP00000092948.1
Reference Protein Sequences
RefSeq Acc Id: XP_017455365   ⟸   XM_017599876
- UniProtKB: A0A8I6GKF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000092948   ⟸   ENSRNOT00000115058

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7500178 AgrOrtholog
BioCyc Gene G2FUF-13776 BioCyc
Ensembl Genes ENSRNOG00000066673 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000115058.1 UniProtKB/TrEMBL
InterPro Zip3/RNF212-like UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report rno:102550789 UniProtKB/TrEMBL
NCBI Gene LOC102550789 ENTREZGENE
PANTHER PTHR22663 UniProtKB/TrEMBL
  RING FINGER PROTEIN 212B UniProtKB/TrEMBL
PhenoGen Rnf212b PhenoGen
PROSITE ZF_RING_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000066673 RatGTEx
UniProt A0A8I6GKF5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Rnf212b  ring finger protein 212B  Rnf212b  ring finger protein 212B  Data merged from RGD:149736408 737654 PROVISIONAL
2021-08-09 Rnf212b  ring finger protein 212B      Symbol and Name status set to provisional 45752 PROVISIONAL
2018-09-06 Rnf212b  ring finger protein 212B  LOC102550789  RING finger protein C14orf164 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102550789  RING finger protein C14orf164 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL