FBXL2 (F-box and leucine rich repeat protein 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: FBXL2 (F-box and leucine rich repeat protein 2) Homo sapiens
Analyze
Symbol: FBXL2
Name: F-box and leucine rich repeat protein 2
RGD ID: 736852
HGNC Page HGNC:13598
Description: Enables phosphatidylinositol 3-kinase regulatory subunit binding activity; protein phosphatase binding activity; and ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; and regulation of signal transduction. Located in membrane. Part of SCF ubiquitin ligase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: DKFZp564P0622; F-box and leucine-rich repeat protein 2; F-box protein containing leucine-rich repeats; F-box protein FBL2/FBL3; F-box/LRR-repeat protein 2; FBL2; FBL3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38333,277,025 - 33,422,698 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl333,277,025 - 33,403,662 (+)EnsemblGRCh38hg38GRCh38
GRCh37333,318,517 - 33,464,190 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36333,293,938 - 33,403,129 (+)NCBINCBI36Build 36hg18NCBI36
Build 34333,293,937 - 33,403,121NCBI
Celera333,262,399 - 33,372,286 (+)NCBICelera
Cytogenetic Map3p22.3NCBI
HuRef333,259,441 - 33,369,309 (+)NCBIHuRef
CHM1_1333,268,994 - 33,378,729 (+)NCBICHM1_1
T2T-CHM13v2.0333,278,817 - 33,424,454 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,TAS)
membrane  (IDA,IEA)
SCF ubiquitin ligase complex  (IDA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Identification of a novel Skp2-like mammalian protein containing F-box and leucine-rich repeats. Ilyin GP, etal., FEBS Lett 1999 Oct 1;459(1):75-9.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10531035   PMID:10531037   PMID:10945468   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15893726   PMID:16169070   PMID:16344560   PMID:17784784   PMID:18160438   PMID:19159283  
PMID:21873635   PMID:22020328   PMID:22323446   PMID:22399757   PMID:22455980   PMID:22939624   PMID:23370391   PMID:23604317   PMID:23928698   PMID:24035498   PMID:25036637   PMID:26037928  
PMID:26790640   PMID:27010866   PMID:27705803   PMID:28514442   PMID:28614300   PMID:29103612   PMID:29987050   PMID:30021884   PMID:31679690   PMID:31953162   PMID:32205409   PMID:32296183  
PMID:32814053   PMID:32938669   PMID:33450386   PMID:33961781   PMID:34635651   PMID:34709416   PMID:36460773   PMID:36662618  


Genomics

Comparative Map Data
FBXL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38333,277,025 - 33,422,698 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl333,277,025 - 33,403,662 (+)EnsemblGRCh38hg38GRCh38
GRCh37333,318,517 - 33,464,190 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36333,293,938 - 33,403,129 (+)NCBINCBI36Build 36hg18NCBI36
Build 34333,293,937 - 33,403,121NCBI
Celera333,262,399 - 33,372,286 (+)NCBICelera
Cytogenetic Map3p22.3NCBI
HuRef333,259,441 - 33,369,309 (+)NCBIHuRef
CHM1_1333,268,994 - 33,378,729 (+)NCBICHM1_1
T2T-CHM13v2.0333,278,817 - 33,424,454 (+)NCBIT2T-CHM13v2.0
Fbxl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399113,787,625 - 113,855,871 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9113,792,705 - 113,875,259 (-)EnsemblGRCm39 Ensembl
GRCm389113,958,557 - 114,026,803 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9113,963,637 - 114,046,191 (-)EnsemblGRCm38mm10GRCm38
MGSCv379113,886,076 - 113,935,869 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369113,825,656 - 113,875,449 (-)NCBIMGSCv36mm8
Celera9113,686,095 - 113,734,801 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map964.17NCBI
Fbxl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88122,794,870 - 122,843,265 (-)NCBIGRCr8
mRatBN7.28113,916,660 - 113,965,137 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8113,913,373 - 113,965,066 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.08122,240,393 - 122,290,439 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8122,243,016 - 122,311,431 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08121,554,708 - 121,603,927 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48118,621,502 - 118,669,052 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera8113,162,143 - 113,212,326 (-)NCBICelera
Cytogenetic Map8q32NCBI
Fbxl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955421512,158 - 617,524 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955421512,197 - 617,524 (+)NCBIChiLan1.0ChiLan1.0
FBXL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2233,256,595 - 33,365,985 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1333,261,360 - 33,370,750 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0333,199,436 - 33,308,831 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1333,501,519 - 33,646,074 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl333,501,525 - 33,610,039 (+)Ensemblpanpan1.1panPan2
FBXL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1233,498,253 - 3,606,016 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl233,498,979 - 3,607,093 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha233,541,659 - 3,650,996 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0233,750,529 - 3,868,136 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl233,749,200 - 3,868,361 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1233,592,258 - 3,701,543 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0233,719,289 - 3,828,653 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0233,692,819 - 3,802,389 (-)NCBIUU_Cfam_GSD_1.0
Fbxl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118190,428,643 - 190,520,703 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647323,567,230 - 23,658,240 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647323,567,251 - 23,659,708 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1319,128,237 - 19,221,201 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11319,128,145 - 19,206,458 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FBXL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11577,769,424 - 77,895,994 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1577,769,748 - 77,878,340 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604151,150,472 - 51,278,268 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478811,253,934 - 11,349,137 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478811,253,912 - 11,350,045 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FBXL2
21 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3p22.3-22.2(chr3:32322382-36775606)x1 copy number loss See cases [RCV000051509] Chr3:32322382..36775606 [GRCh38]
Chr3:32363874..36817097 [GRCh37]
Chr3:32338878..36792101 [NCBI36]
Chr3:3p22.3-22.2		 pathogenic
GRCh38/hg38 3p22.3-22.2(chr3:33062199-36829440)x1 copy number loss See cases [RCV000051510] Chr3:33062199..36829440 [GRCh38]
Chr3:33103691..36870931 [GRCh37]
Chr3:33078695..36845935 [NCBI36]
Chr3:3p22.3-22.2		 pathogenic
GRCh38/hg38 3p26.3-22.2(chr3:52266-37148076)x3 copy number gain See cases [RCV000051097] Chr3:52266..37148076 [GRCh38]
Chr3:93949..37189567 [GRCh37]
Chr3:68949..37164571 [NCBI36]
Chr3:3p26.3-22.2		 pathogenic
GRCh38/hg38 3p25.3-22.2(chr3:11463328-38919543)x3 copy number gain See cases [RCV000051720] Chr3:11463328..38919543 [GRCh38]
Chr3:11504802..38961034 [GRCh37]
Chr3:11479802..38936038 [NCBI36]
Chr3:3p25.3-22.2		 pathogenic
GRCh38/hg38 3p26.3-22.1(chr3:53308-41381521)x3 copy number gain See cases [RCV000141810] Chr3:53308..41381521 [GRCh38]
Chr3:94991..41423012 [GRCh37]
Chr3:69991..41398016 [NCBI36]
Chr3:3p26.3-22.1		 pathogenic
GRCh37/hg19 3p24.1-22.3(chr3:29689082-34233218)x1 copy number loss See cases [RCV000240426] Chr3:29689082..34233218 [GRCh37]
Chr3:3p24.1-22.3		 pathogenic
GRCh37/hg19 3p26.3-22.2(chr3:61891-36710181)x3 copy number gain See cases [RCV000448528] Chr3:61891..36710181 [GRCh37]
Chr3:3p26.3-22.2		 pathogenic
GRCh37/hg19 3p26.3-22.3(chr3:61891-33958201)x3 copy number gain See cases [RCV000510429] Chr3:61891..33958201 [GRCh37]
Chr3:3p26.3-22.3		 pathogenic
GRCh37/hg19 3p26.3-22.2(chr3:61891-37459464)x3 copy number gain See cases [RCV000511463] Chr3:61891..37459464 [GRCh37]
Chr3:3p26.3-22.2		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_014517.5(UBP1):c.479C>G (p.Thr160Arg) single nucleotide variant not specified [RCV004288667] Chr3:33411657 [GRCh38]
Chr3:33453149 [GRCh37]
Chr3:3p22.3		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p24.3-21.31(chr3:16923595-45249923)x2,3 copy number gain not provided [RCV000682249] Chr3:16923595..45249923 [GRCh37]
Chr3:3p24.3-21.31		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_014517.5(UBP1):c.1081G>A (p.Gly361Ser) single nucleotide variant not specified [RCV004314816] Chr3:33400967 [GRCh38]
Chr3:33442459 [GRCh37]
Chr3:3p22.3		 likely benign
NM_012157.5(FBXL2):c.200G>A (p.Arg67Gln) single nucleotide variant not specified [RCV004307243] Chr3:33364629 [GRCh38]
Chr3:33406121 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_012157.5(FBXL2):c.161G>T (p.Arg54Ile) single nucleotide variant not specified [RCV004309999] Chr3:33359323 [GRCh38]
Chr3:33400815 [GRCh37]
Chr3:3p22.3		 uncertain significance
GRCh37/hg19 3p22.3(chr3:32699328-35286114) copy number gain not specified [RCV002053338] Chr3:32699328..35286114 [GRCh37]
Chr3:3p22.3		 uncertain significance
GRCh37/hg19 3p26.3-22.2(chr3:61891-36710181) copy number gain not specified [RCV002053300] Chr3:61891..36710181 [GRCh37]
Chr3:3p26.3-22.2		 pathogenic
NC_000003.11:g.(?_16710965)_(41275270_?)del deletion not provided [RCV001958625] Chr3:16710965..41275270 [GRCh37]
Chr3:3p24.3-22.1		 pathogenic
NM_014517.5(UBP1):c.698A>G (p.Lys233Arg) single nucleotide variant not specified [RCV004137809] Chr3:33409459 [GRCh38]
Chr3:33450951 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.1323C>G (p.Ser441Arg) single nucleotide variant not specified [RCV004095162] Chr3:33396229 [GRCh38]
Chr3:33437721 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.296A>T (p.Asn99Ile) single nucleotide variant not specified [RCV004169086] Chr3:33416804 [GRCh38]
Chr3:33458296 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_012157.5(FBXL2):c.1020T>G (p.His340Gln) single nucleotide variant not specified [RCV004132173] Chr3:33384057 [GRCh38]
Chr3:33425549 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_012157.5(FBXL2):c.907A>C (p.Thr303Pro) single nucleotide variant not specified [RCV004152283] Chr3:33378697 [GRCh38]
Chr3:33420189 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.1306C>T (p.Arg436Trp) single nucleotide variant not specified [RCV004227755] Chr3:33396246 [GRCh38]
Chr3:33437738 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.1499G>T (p.Gly500Val) single nucleotide variant not specified [RCV004235223] Chr3:33393346 [GRCh38]
Chr3:33434838 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.979C>A (p.Pro327Thr) single nucleotide variant not specified [RCV004212690] Chr3:33402853 [GRCh38]
Chr3:33444345 [GRCh37]
Chr3:3p22.3		 likely benign
NM_012157.5(FBXL2):c.806G>A (p.Arg269Gln) single nucleotide variant not specified [RCV004241212] Chr3:33377290 [GRCh38]
Chr3:33418782 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.1363A>G (p.Ser455Gly) single nucleotide variant not specified [RCV004163359] Chr3:33396189 [GRCh38]
Chr3:33437681 [GRCh37]
Chr3:3p22.3		 likely benign
NM_012157.5(FBXL2):c.341G>A (p.Cys114Tyr) single nucleotide variant not specified [RCV004136544] Chr3:33373142 [GRCh38]
Chr3:33414634 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.808A>G (p.Ile270Val) single nucleotide variant not specified [RCV004219178] Chr3:33409247 [GRCh38]
Chr3:33450739 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.452T>C (p.Ile151Thr) single nucleotide variant not specified [RCV004266026] Chr3:33411684 [GRCh38]
Chr3:33453176 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.1105A>G (p.Thr369Ala) single nucleotide variant not specified [RCV004321890] Chr3:33400264 [GRCh38]
Chr3:33441756 [GRCh37]
Chr3:3p22.3		 uncertain significance
GRCh37/hg19 3p22.3(chr3:32324460-33982773)x3 copy number gain not provided [RCV003484125] Chr3:32324460..33982773 [GRCh37]
Chr3:3p22.3		 uncertain significance
GRCh37/hg19 3p26.3-22.3(chr3:61891-33946644)x3 copy number gain not specified [RCV003986437] Chr3:61891..33946644 [GRCh37]
Chr3:3p26.3-22.3		 pathogenic
NM_012157.5(FBXL2):c.1207G>A (p.Val403Ile) single nucleotide variant not specified [RCV004378896] Chr3:33385543 [GRCh38]
Chr3:33427035 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_012157.5(FBXL2):c.405G>C (p.Leu135=) single nucleotide variant not specified [RCV004378897] Chr3:33373305 [GRCh38]
Chr3:33414797 [GRCh37]
Chr3:3p22.3		 likely benign
NM_014517.5(UBP1):c.1052A>G (p.His351Arg) single nucleotide variant not specified [RCV004477036] Chr3:33400996 [GRCh38]
Chr3:33442488 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.997T>C (p.Ser333Pro) single nucleotide variant not specified [RCV004477038] Chr3:33402835 [GRCh38]
Chr3:33444327 [GRCh37]
Chr3:3p22.3		 uncertain significance
NM_014517.5(UBP1):c.998C>T (p.Ser333Phe) single nucleotide variant not specified [RCV004477039] Chr3:33402834 [GRCh38]
Chr3:33444326 [GRCh37]
Chr3:3p22.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:7425
Count of miRNA genes:1205
Interacting mature miRNAs:1534
Transcripts:ENST00000283627, ENST00000421391, ENST00000422741, ENST00000425973, ENST00000432809, ENST00000435207, ENST00000446237, ENST00000451636, ENST00000460186, ENST00000461094, ENST00000463698, ENST00000463736, ENST00000464164, ENST00000464990, ENST00000471208, ENST00000483037, ENST00000484457, ENST00000492662, ENST00000493778, ENST00000497411, ENST00000498807, ENST00000507198, ENST00000538181, ENST00000538892, ENST00000542085
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
HSC28B082  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37333,427,875 - 33,428,079UniSTSGRCh37
Build 36333,402,879 - 33,403,083RGDNCBI36
Celera333,371,404 - 33,371,608RGD
Cytogenetic Map3p22.3UniSTS
HuRef333,368,423 - 33,368,627UniSTS
GeneMap99-GB4 RH Map3122.42UniSTS
Whitehead-RH Map3130.4UniSTS
G63013  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37333,347,400 - 33,347,729UniSTSGRCh37
Build 36333,322,404 - 33,322,733RGDNCBI36
Celera333,290,846 - 33,291,175RGD
Cytogenetic Map3p22.3UniSTS
HuRef333,287,962 - 33,288,291UniSTS
TNG Radiation Hybrid Map320643.0UniSTS
G63277  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37333,347,400 - 33,347,740UniSTSGRCh37
Build 36333,322,404 - 33,322,744RGDNCBI36
Celera333,290,846 - 33,291,186RGD
Cytogenetic Map3p22.3UniSTS
HuRef333,287,962 - 33,288,302UniSTS
TNG Radiation Hybrid Map320646.0UniSTS
D3S3815  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37333,427,786 - 33,427,974UniSTSGRCh37
Build 36333,402,790 - 33,402,978RGDNCBI36
Celera333,371,315 - 33,371,503RGD
Cytogenetic Map3p22.3UniSTS
HuRef333,368,334 - 33,368,522UniSTS
GeneMap99-GB4 RH Map3124.02UniSTS
Whitehead-RH Map3130.3UniSTS
Whitehead-YAC Contig Map3 UniSTS
NCBI RH Map3342.2UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 43 1047 773 2 3 3 754 18 1525 37 504 529 2 1 16 749
Low 2296 1047 622 292 819 133 2917 1363 2200 378 954 1082 172 1188 1360 6 2
Below cutoff 97 874 330 329 1096 328 685 815 9 4 2 2 1 679

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001349316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_146135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005265015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011533559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017006093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024453440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054346016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054346017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008486694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008486695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008486696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC122176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF174589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF176518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF186273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK096492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK302218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL049953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU124816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR457121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA031508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY138078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000283627
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,446 - 33,386,476 (+)Ensembl
RefSeq Acc Id: ENST00000421391   ⟹   ENSP00000408895
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,477 - 33,385,862 (+)Ensembl
RefSeq Acc Id: ENST00000422741   ⟹   ENSP00000406737
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,476 - 33,386,633 (+)Ensembl
RefSeq Acc Id: ENST00000425973   ⟹   ENSP00000405084
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,472 - 33,373,319 (+)Ensembl
RefSeq Acc Id: ENST00000432809   ⟹   ENSP00000411273
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,451 - 33,386,023 (+)Ensembl
RefSeq Acc Id: ENST00000435207   ⟹   ENSP00000411484
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,445 - 33,385,621 (+)Ensembl
RefSeq Acc Id: ENST00000451636   ⟹   ENSP00000416332
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,453 - 33,385,948 (+)Ensembl
RefSeq Acc Id: ENST00000460186
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,372,988 - 33,375,366 (+)Ensembl
RefSeq Acc Id: ENST00000461094
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,364,336 - 33,373,618 (+)Ensembl
RefSeq Acc Id: ENST00000463698
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,372,341 - 33,373,639 (+)Ensembl
RefSeq Acc Id: ENST00000463736
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,466 - 33,403,662 (+)Ensembl
RefSeq Acc Id: ENST00000464164
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,289,669 - 33,373,303 (+)Ensembl
RefSeq Acc Id: ENST00000464990
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,382,552 - 33,386,625 (+)Ensembl
RefSeq Acc Id: ENST00000471208
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,373,276 - 33,373,924 (+)Ensembl
RefSeq Acc Id: ENST00000483037
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,278,173 - 33,359,358 (+)Ensembl
RefSeq Acc Id: ENST00000484457   ⟹   ENSP00000417601
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,442 - 33,388,092 (+)Ensembl
RefSeq Acc Id: ENST00000492662
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,373,021 - 33,375,407 (+)Ensembl
RefSeq Acc Id: ENST00000493778
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,289,650 - 33,373,311 (+)Ensembl
RefSeq Acc Id: ENST00000497411
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,445 - 33,373,601 (+)Ensembl
RefSeq Acc Id: ENST00000498807
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,025 - 33,373,295 (+)Ensembl
RefSeq Acc Id: ENST00000538892   ⟹   ENSP00000441228
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl333,277,445 - 33,387,265 (+)Ensembl
RefSeq Acc Id: NM_001349316   ⟹   NP_001336245
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001349319   ⟹   NP_001336248
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,025 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,278,817 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001349320   ⟹   NP_001336249
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001349321   ⟹   NP_001336250
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001349322   ⟹   NP_001336251
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001349323   ⟹   NP_001336252
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,025 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,278,817 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001349324   ⟹   NP_001336253
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001349325   ⟹   NP_001336254
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001349326   ⟹   NP_001336255
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NM_012157   ⟹   NP_036289
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
GRCh37333,318,934 - 33,445,505 (+)NCBI
Build 36333,293,938 - 33,403,129 (+)NCBI Archive
Celera333,262,399 - 33,372,286 (+)RGD
HuRef333,259,441 - 33,369,309 (+)ENTREZGENE
CHM1_1333,268,994 - 33,378,729 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146121
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,025 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,278,817 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146122
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,025 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,278,817 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146123
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,422,698 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,424,454 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146124
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,403,662 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,405,423 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146125
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,403,662 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,405,423 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146126
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146127
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,403,662 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,405,423 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146128
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,403,662 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,405,423 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146129
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,403,662 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,405,423 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146130
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146131
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146132
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,422,698 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,424,454 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146133
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146134
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: NR_146135
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,388,092 (+)NCBI
T2T-CHM13v2.0333,279,236 - 33,389,860 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054346016   ⟹   XP_054201991
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0333,291,298 - 33,389,860 (+)NCBI
RefSeq Acc Id: XM_054346017   ⟹   XP_054201992
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0333,291,445 - 33,389,860 (+)NCBI
RefSeq Acc Id: XR_007095659
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,403,662 (+)NCBI
RefSeq Acc Id: XR_008486694
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0333,291,298 - 33,405,423 (+)NCBI
RefSeq Acc Id: XR_008486695
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0333,279,236 - 33,405,423 (+)NCBI
RefSeq Acc Id: XR_008486696
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0333,291,445 - 33,405,423 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001336245 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336248 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336249 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336250 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336251 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336252 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336253 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336254 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336255 (Get FASTA)   NCBI Sequence Viewer  
  NP_036289 (Get FASTA)   NCBI Sequence Viewer  
  XP_054201991 (Get FASTA)   NCBI Sequence Viewer  
  XP_054201992 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD56248 (Get FASTA)   NCBI Sequence Viewer  
  AAF03128 (Get FASTA)   NCBI Sequence Viewer  
  AAF04510 (Get FASTA)   NCBI Sequence Viewer  
  AAH31556 (Get FASTA)   NCBI Sequence Viewer  
  BAA91691 (Get FASTA)   NCBI Sequence Viewer  
  BAG50882 (Get FASTA)   NCBI Sequence Viewer  
  BAG57520 (Get FASTA)   NCBI Sequence Viewer  
  BAG59935 (Get FASTA)   NCBI Sequence Viewer  
  BAG61062 (Get FASTA)   NCBI Sequence Viewer  
  BAG61579 (Get FASTA)   NCBI Sequence Viewer  
  BAG63574 (Get FASTA)   NCBI Sequence Viewer  
  BAG64730 (Get FASTA)   NCBI Sequence Viewer  
  BAH14600 (Get FASTA)   NCBI Sequence Viewer  
  BAH14754 (Get FASTA)   NCBI Sequence Viewer  
  CAB43222 (Get FASTA)   NCBI Sequence Viewer  
  CAG33402 (Get FASTA)   NCBI Sequence Viewer  
  EAW64452 (Get FASTA)   NCBI Sequence Viewer  
  EAW64453 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000405084.1
  ENSP00000406737.1
  ENSP00000408895.1
  ENSP00000411273.1
  ENSP00000411484.1
  ENSP00000416332.1
  ENSP00000417601
  ENSP00000417601.1
GenBank Protein Q9UKC9 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_036289   ⟸   NM_012157
- Peptide Label: isoform 1
- UniProtKB: Q9UKA5 (UniProtKB/Swiss-Prot),   Q9UK27 (UniProtKB/Swiss-Prot),   Q9NVQ8 (UniProtKB/Swiss-Prot),   Q6IAN3 (UniProtKB/Swiss-Prot),   E9PD06 (UniProtKB/Swiss-Prot),   B4DQV0 (UniProtKB/Swiss-Prot),   Q9Y3Y9 (UniProtKB/Swiss-Prot),   Q9UKC9 (UniProtKB/Swiss-Prot),   B3KM70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001336248   ⟸   NM_001349319
- Peptide Label: isoform 4
- Sequence:
RefSeq Acc Id: NP_001336252   ⟸   NM_001349323
- Peptide Label: isoform 6
- UniProtKB: B4DMM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001336255   ⟸   NM_001349326
- Peptide Label: isoform 6
- UniProtKB: B4DMM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001336250   ⟸   NM_001349321
- Peptide Label: isoform 4
- Sequence:
RefSeq Acc Id: NP_001336254   ⟸   NM_001349325
- Peptide Label: isoform 6
- UniProtKB: B4DMM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001336251   ⟸   NM_001349322
- Peptide Label: isoform 5 precursor
- UniProtKB: B4E1B8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001336249   ⟸   NM_001349320
- Peptide Label: isoform 4
- Sequence:
RefSeq Acc Id: NP_001336253   ⟸   NM_001349324
- Peptide Label: isoform 6
- UniProtKB: B4DMM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001336245   ⟸   NM_001349316
- Peptide Label: isoform 3
- UniProtKB: B3KM70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000405084   ⟸   ENST00000425973
RefSeq Acc Id: ENSP00000416332   ⟸   ENST00000451636
RefSeq Acc Id: ENSP00000417601   ⟸   ENST00000484457
RefSeq Acc Id: ENSP00000441228   ⟸   ENST00000538892
RefSeq Acc Id: ENSP00000411273   ⟸   ENST00000432809
RefSeq Acc Id: ENSP00000408895   ⟸   ENST00000421391
RefSeq Acc Id: ENSP00000411484   ⟸   ENST00000435207
RefSeq Acc Id: ENSP00000406737   ⟸   ENST00000422741
RefSeq Acc Id: XP_054201991   ⟸   XM_054346016
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054201992   ⟸   XM_054346017
- Peptide Label: isoform X2
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9UKC9-F1-model_v2 AlphaFold Q9UKC9 1-423 view protein structure

Promoters
RGD ID:6863920
Promoter ID:EPDNEW_H5125
Type:initiation region
Name:FBXL2_1
Description:F-box and leucine rich repeat protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38333,277,442 - 33,277,502EPDNEW
RGD ID:6801039
Promoter ID:HG_KWN:44278
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:NM_001171713,   OTTHUMT00000253245,   OTTHUMT00000342306,   OTTHUMT00000342307,   OTTHUMT00000342308,   OTTHUMT00000342309,   OTTHUMT00000342310,   OTTHUMT00000342311,   OTTHUMT00000342312,   OTTHUMT00000342313,   OTTHUMT00000342365,   OTTHUMT00000342369,   OTTHUMT00000342370
Position:
Human AssemblyChrPosition (strand)Source
Build 36333,293,741 - 33,294,241 (+)MPROMDB
RGD ID:6801047
Promoter ID:HG_KWN:44279
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:OTTHUMT00000342366,   OTTHUMT00000342371
Position:
Human AssemblyChrPosition (strand)Source
Build 36333,293,806 - 33,294,306 (+)MPROMDB
RGD ID:6801040
Promoter ID:HG_KWN:44282
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell
Transcripts:OTTHUMT00000342372,   OTTHUMT00000342439,   OTTHUMT00000342440,   OTTHUMT00000342441
Position:
Human AssemblyChrPosition (strand)Source
Build 36333,389,161 - 33,389,661 (+)MPROMDB
RGD ID:6801036
Promoter ID:HG_KWN:44283
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   K562,   Lymphoblastoid
Transcripts:OTTHUMT00000342314
Position:
Human AssemblyChrPosition (strand)Source
Build 36333,398,531 - 33,400,567 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:13598 AgrOrtholog
COSMIC FBXL2 COSMIC
Ensembl Genes ENSG00000153558 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000421391.5 UniProtKB/TrEMBL
  ENST00000422741.5 UniProtKB/TrEMBL
  ENST00000425973.5 UniProtKB/TrEMBL
  ENST00000432809.5 UniProtKB/TrEMBL
  ENST00000435207.5 UniProtKB/TrEMBL
  ENST00000451636.5 UniProtKB/TrEMBL
  ENST00000463736 ENTREZGENE
  ENST00000484457 ENTREZGENE
  ENST00000484457.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1280.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000153558 GTEx
HGNC ID HGNC:13598 ENTREZGENE
Human Proteome Map FBXL2 Human Proteome Map
InterPro F-box_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-box_dom_like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_Cys-con_subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:25827 UniProtKB/Swiss-Prot
NCBI Gene 25827 ENTREZGENE
OMIM 605652 OMIM
PANTHER F-BOX_LRR PROTEIN UniProtKB/TrEMBL
  MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN AMN1 HOMOLOG UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA28021 PharmGKB
PROSITE FBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP F-box_dom_Skp2-like UniProtKB/TrEMBL
  RNI-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B3KM70 ENTREZGENE, UniProtKB/TrEMBL
  B4DMM3 ENTREZGENE, UniProtKB/TrEMBL
  B4DQV0 ENTREZGENE
  B4E1B8 ENTREZGENE, UniProtKB/TrEMBL
  E9PD06 ENTREZGENE
  F8WB01_HUMAN UniProtKB/TrEMBL
  F8WBS9_HUMAN UniProtKB/TrEMBL
  F8WBW7_HUMAN UniProtKB/TrEMBL
  F8WC58_HUMAN UniProtKB/TrEMBL
  F8WCQ8_HUMAN UniProtKB/TrEMBL
  F8WE99_HUMAN UniProtKB/TrEMBL
  FBXL2_HUMAN UniProtKB/Swiss-Prot
  Q6IAN3 ENTREZGENE
  Q9NVQ8 ENTREZGENE
  Q9UK27 ENTREZGENE
  Q9UKA5 ENTREZGENE
  Q9UKC9 ENTREZGENE
  Q9Y3Y9 ENTREZGENE
UniProt Secondary B4DQV0 UniProtKB/Swiss-Prot
  E9PD06 UniProtKB/Swiss-Prot
  Q6IAN3 UniProtKB/Swiss-Prot
  Q9NVQ8 UniProtKB/Swiss-Prot
  Q9UK27 UniProtKB/Swiss-Prot
  Q9UKA5 UniProtKB/Swiss-Prot
  Q9Y3Y9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-14 FBXL2  F-box and leucine rich repeat protein 2    F-box and leucine-rich repeat protein 2  Symbol and/or name change 5135510 APPROVED