SYT13 (synaptotagmin 13) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: SYT13 (synaptotagmin 13) Homo sapiens
Analyze
Symbol: SYT13
Name: synaptotagmin 13
RGD ID: 735243
HGNC Page HGNC:14962
Description: Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Predicted to be involved in calcium-ion regulated exocytosis; cellular response to calcium ion; and regulation of secretion by cell. Predicted to act upstream of or within vesicle-mediated transport. Located in transport vesicle.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: KIAA1427; synaptotagmin XIII; synaptotagmin-13; sytXIII
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381145,240,302 - 45,286,341 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1145,240,302 - 45,286,341 (-)EnsemblGRCh38hg38GRCh38
GRCh371145,261,853 - 45,307,892 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361145,218,429 - 45,264,383 (-)NCBINCBI36Build 36hg18NCBI36
Build 341145,218,428 - 45,264,383NCBI
Celera1145,409,536 - 45,455,569 (-)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1144,971,578 - 45,017,603 (-)NCBIHuRef
CHM1_11145,260,943 - 45,306,976 (-)NCBICHM1_1
T2T-CHM13v2.01145,397,823 - 45,443,869 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889549   PMID:10718198   PMID:11076863   PMID:11171101   PMID:11230166   PMID:11256614   PMID:11543631   PMID:12477932   PMID:15342556   PMID:15489334   PMID:15489336   PMID:16381901  
PMID:18202767   PMID:20379614   PMID:20840848   PMID:21873635   PMID:22632162   PMID:29741294   PMID:30021884   PMID:31055693   PMID:31625195   PMID:31939613   PMID:32065260   PMID:33961781  
PMID:34677264   PMID:35337019   PMID:35753051   PMID:36630025  


Genomics

Comparative Map Data
SYT13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381145,240,302 - 45,286,341 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1145,240,302 - 45,286,341 (-)EnsemblGRCh38hg38GRCh38
GRCh371145,261,853 - 45,307,892 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361145,218,429 - 45,264,383 (-)NCBINCBI36Build 36hg18NCBI36
Build 341145,218,428 - 45,264,383NCBI
Celera1145,409,536 - 45,455,569 (-)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1144,971,578 - 45,017,603 (-)NCBIHuRef
CHM1_11145,260,943 - 45,306,976 (-)NCBICHM1_1
T2T-CHM13v2.01145,397,823 - 45,443,869 (-)NCBIT2T-CHM13v2.0
Syt13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39292,745,446 - 92,786,403 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl292,745,443 - 92,786,403 (+)EnsemblGRCm39 Ensembl
GRCm38292,915,101 - 92,956,051 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl292,915,098 - 92,956,058 (+)EnsemblGRCm38mm10GRCm38
MGSCv37292,755,258 - 92,796,208 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36292,715,940 - 92,756,890 (+)NCBIMGSCv36mm8
Celera294,309,422 - 94,350,401 (+)NCBICelera
Cytogenetic Map2E1NCBI
cM Map251.37NCBI
Syt13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8399,332,554 - 99,372,960 (+)NCBIGRCr8
mRatBN7.2378,877,114 - 78,917,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl378,877,114 - 78,917,392 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx382,352,838 - 82,389,785 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0390,951,885 - 90,988,833 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0388,803,139 - 88,840,217 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0381,814,287 - 81,852,454 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl381,814,261 - 81,854,605 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0388,516,996 - 88,555,163 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4377,317,878 - 77,356,047 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1377,214,229 - 77,252,539 (+)NCBI
Celera378,081,337 - 78,119,548 (+)NCBICelera
Cytogenetic Map3q31NCBI
Syt13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554222,561,373 - 2,601,823 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554222,561,660 - 2,600,863 (+)NCBIChiLan1.0ChiLan1.0
SYT13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2947,452,120 - 47,498,245 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11147,458,764 - 47,504,873 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01145,197,691 - 45,243,814 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11145,690,894 - 45,736,503 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1145,690,894 - 45,736,503 (-)Ensemblpanpan1.1panPan2
SYT13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11844,061,220 - 44,105,742 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1844,061,271 - 44,102,382 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1842,789,172 - 42,833,682 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01844,717,536 - 44,762,060 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1844,717,529 - 44,762,063 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11844,201,700 - 44,246,169 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01843,755,171 - 43,799,823 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01844,487,469 - 44,531,997 (+)NCBIUU_Cfam_GSD_1.0
Syt13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494721,487,774 - 21,501,096 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365623,599,400 - 3,614,829 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365623,596,283 - 3,612,689 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYT13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl217,120,634 - 17,166,990 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1217,120,127 - 17,166,997 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2218,596,983 - 18,640,224 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SYT13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1120,054,549 - 20,101,574 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl120,054,827 - 20,104,144 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038117,313,631 - 117,359,849 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syt13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247673,073,168 - 3,122,183 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247673,073,269 - 3,121,172 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SYT13
19 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11p11.2(chr11:45272625-45532378)x3 copy number gain See cases [RCV000051906] Chr11:45272625..45532378 [GRCh38]
Chr11:45294176..45553928 [GRCh37]
Chr11:45250752..45510504 [NCBI36]
Chr11:11p11.2		 uncertain significance
GRCh38/hg38 11p13-11.2(chr11:35663578-46959820)x1 copy number loss See cases [RCV000052679] Chr11:35663578..46959820 [GRCh38]
Chr11:35685126..46981371 [GRCh37]
Chr11:35641702..46937947 [NCBI36]
Chr11:11p13-11.2		 pathogenic
GRCh38/hg38 11p12-11.2(chr11:36508280-48643003)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052680]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052680]|See cases [RCV000052680] Chr11:36508280..48643003 [GRCh38]
Chr11:36529830..48664555 [GRCh37]
Chr11:36486406..48621131 [NCBI36]
Chr11:11p12-11.2		 pathogenic
GRCh38/hg38 11p11.2(chr11:44136593-46121139)x1 copy number loss See cases [RCV000052681] Chr11:44136593..46121139 [GRCh38]
Chr11:44158143..46142690 [GRCh37]
Chr11:44114719..46099266 [NCBI36]
Chr11:11p11.2		 pathogenic
GRCh38/hg38 11p12-11.2(chr11:41118322-48643003)x1 copy number loss See cases [RCV000135405] Chr11:41118322..48643003 [GRCh38]
Chr11:41139872..48664555 [GRCh37]
Chr11:41096448..48621131 [NCBI36]
Chr11:11p12-11.2		 pathogenic
GRCh38/hg38 11p12-11.12(chr11:39179252-49135735)x1 copy number loss See cases [RCV000137391] Chr11:39179252..49135735 [GRCh38]
Chr11:39200802..49157287 [GRCh37]
Chr11:39157378..49113863 [NCBI36]
Chr11:11p12-11.12		 pathogenic
GRCh38/hg38 11p12-11.12(chr11:42727555-49135735)x3 copy number gain See cases [RCV000139422] Chr11:42727555..49135735 [GRCh38]
Chr11:42749105..49157287 [GRCh37]
Chr11:42705681..49113863 [NCBI36]
Chr11:11p12-11.12		 likely pathogenic
GRCh38/hg38 11p12-11.2(chr11:42553659-46114792)x1 copy number loss See cases [RCV000142289] Chr11:42553659..46114792 [GRCh38]
Chr11:42575209..46136343 [GRCh37]
Chr11:42531785..46092919 [NCBI36]
Chr11:11p12-11.2		 pathogenic
GRCh37/hg19 11p12-11.2(chr11:42475897-48372559)x1 copy number loss See cases [RCV000446383] Chr11:42475897..48372559 [GRCh37]
Chr11:11p12-11.2		 pathogenic
GRCh37/hg19 11p14.1-11.2(chr11:29238811-45494063)x1 copy number loss See cases [RCV000445800] Chr11:29238811..45494063 [GRCh37]
Chr11:11p14.1-11.2		 pathogenic
GRCh37/hg19 11p14.2-11.12(chr11:26574629-50508019)x3 copy number gain See cases [RCV000448603] Chr11:26574629..50508019 [GRCh37]
Chr11:11p14.2-11.12		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p11.2(chr11:45229091-46342834)x3 copy number gain not provided [RCV000750026] Chr11:45229091..46342834 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.471C>T (p.Asn157=) single nucleotide variant not provided [RCV000888137] Chr11:45254343 [GRCh38]
Chr11:45275894 [GRCh37]
Chr11:11p11.2		 benign
NM_020826.3(SYT13):c.103C>A (p.Pro35Thr) single nucleotide variant not specified [RCV004306903] Chr11:45286105 [GRCh38]
Chr11:45307656 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.851C>A (p.Pro284Gln) single nucleotide variant not specified [RCV004332927] Chr11:45246508 [GRCh38]
Chr11:45268059 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.786G>A (p.Leu262=) single nucleotide variant not provided [RCV000976537] Chr11:45252481 [GRCh38]
Chr11:45274032 [GRCh37]
Chr11:11p11.2		 benign
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
GRCh37/hg19 11p11.2(chr11:44266593-46123796)x4 copy number gain not provided [RCV001259092] Chr11:44266593..46123796 [GRCh37]
Chr11:11p11.2		 uncertain significance
GRCh37/hg19 11p11.2(chr11:45287267-45599960)x3 copy number gain not provided [RCV001827753] Chr11:45287267..45599960 [GRCh37]
Chr11:11p11.2		 uncertain significance
GRCh37/hg19 11p12-11.2(chr11:40117145-46920718)x1 copy number loss not provided [RCV001836486] Chr11:40117145..46920718 [GRCh37]
Chr11:11p12-11.2		 pathogenic
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
GRCh37/hg19 11p11.2-q12.2(chr11:51581311-54891247)x3 copy number gain See cases [RCV002286338] Chr11:51581311..54891247 [GRCh37]
Chr11:11p11.2-q12.2		 pathogenic
NM_020826.3(SYT13):c.787G>T (p.Asp263Tyr) single nucleotide variant not specified [RCV004294776] Chr11:45252480 [GRCh38]
Chr11:45274031 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.527T>C (p.Phe176Ser) single nucleotide variant not specified [RCV004332192] Chr11:45254287 [GRCh38]
Chr11:45275838 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.1199C>T (p.Ser400Leu) single nucleotide variant not specified [RCV004156890] Chr11:45244134 [GRCh38]
Chr11:45265685 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.101A>C (p.His34Pro) single nucleotide variant not specified [RCV004081535] Chr11:45286107 [GRCh38]
Chr11:45307658 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.211G>C (p.Val71Leu) single nucleotide variant not specified [RCV004153799] Chr11:45255864 [GRCh38]
Chr11:45277415 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.191T>G (p.Val64Gly) single nucleotide variant not specified [RCV004197426] Chr11:45255884 [GRCh38]
Chr11:45277435 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.1193A>T (p.His398Leu) single nucleotide variant not specified [RCV004171649] Chr11:45244140 [GRCh38]
Chr11:45265691 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.1077G>C (p.Met359Ile) single nucleotide variant not specified [RCV004173152] Chr11:45244256 [GRCh38]
Chr11:45265807 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.169G>C (p.Gly57Arg) single nucleotide variant not specified [RCV004182375] Chr11:45286039 [GRCh38]
Chr11:45307590 [GRCh37]
Chr11:11p11.2		 likely benign
NM_020826.3(SYT13):c.606G>T (p.Arg202Ser) single nucleotide variant not specified [RCV004160430] Chr11:45252661 [GRCh38]
Chr11:45274212 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.719C>T (p.Thr240Met) single nucleotide variant not specified [RCV004163419] Chr11:45252548 [GRCh38]
Chr11:45274099 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.371G>T (p.Arg124Met) single nucleotide variant not specified [RCV004231010] Chr11:45255704 [GRCh38]
Chr11:45277255 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.361C>G (p.Arg121Gly) single nucleotide variant not specified [RCV004255643] Chr11:45255714 [GRCh38]
Chr11:45277265 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.427T>A (p.Cys143Ser) single nucleotide variant not specified [RCV004361141] Chr11:45254387 [GRCh38]
Chr11:45275938 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.644G>C (p.Arg215Pro) single nucleotide variant not specified [RCV004359495] Chr11:45252623 [GRCh38]
Chr11:45274174 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.776G>A (p.Arg259His) single nucleotide variant not specified [RCV004465874] Chr11:45252491 [GRCh38]
Chr11:45274042 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.854C>G (p.Ser285Cys) single nucleotide variant not specified [RCV004465877] Chr11:45246505 [GRCh38]
Chr11:45268056 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.203C>T (p.Thr68Met) single nucleotide variant not specified [RCV004463888] Chr11:45255872 [GRCh38]
Chr11:45277423 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.499G>A (p.Asp167Asn) single nucleotide variant not specified [RCV004463890] Chr11:45254315 [GRCh38]
Chr11:45275866 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.269C>T (p.Thr90Met) single nucleotide variant not specified [RCV004463889] Chr11:45255806 [GRCh38]
Chr11:45277357 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.800T>C (p.Val267Ala) single nucleotide variant not specified [RCV004465875] Chr11:45252467 [GRCh38]
Chr11:45274018 [GRCh37]
Chr11:11p11.2		 uncertain significance
NM_020826.3(SYT13):c.814G>T (p.Ala272Ser) single nucleotide variant not specified [RCV004465876] Chr11:45252453 [GRCh38]
Chr11:45274004 [GRCh37]
Chr11:11p11.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2670
Count of miRNA genes:1158
Interacting mature miRNAs:1428
Transcripts:ENST00000020926, ENST00000528101, ENST00000533332
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
WI-14707  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371145,264,387 - 45,264,512UniSTSGRCh37
Build 361145,220,963 - 45,221,088RGDNCBI36
Celera1145,412,071 - 45,412,196RGD
Cytogenetic Map11p12-p11UniSTS
HuRef1144,974,115 - 44,974,240UniSTS
GeneMap99-GB4 RH Map11157.31UniSTS
Whitehead-RH Map11148.8UniSTS
NCBI RH Map11297.1UniSTS
HSC1SF092  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371145,264,387 - 45,264,561UniSTSGRCh37
Build 361145,220,963 - 45,221,137RGDNCBI36
Celera1145,412,071 - 45,412,245RGD
Cytogenetic Map11p12-p11UniSTS
HuRef1144,974,115 - 44,974,289UniSTS
GeneMap99-GB4 RH Map11161.7UniSTS
Whitehead-RH Map11154.4UniSTS
NCBI RH Map11297.1UniSTS
D11S3115  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371145,272,295 - 45,272,410UniSTSGRCh37
Build 361145,228,871 - 45,228,986RGDNCBI36
Celera1145,419,979 - 45,420,094RGD
Cytogenetic Map11p12-p11UniSTS
HuRef1144,982,022 - 44,982,137UniSTS
RH18313  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371145,262,298 - 45,262,480UniSTSGRCh37
Build 361145,218,874 - 45,219,056RGDNCBI36
Celera1145,409,981 - 45,410,163RGD
Cytogenetic Map11p12-p11UniSTS
HuRef1144,972,023 - 44,972,205UniSTS
GeneMap99-GB4 RH Map11159.48UniSTS
NCBI RH Map11297.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 214 41 307 29 35 28 160 6 1862 197 112 97 4 1
Low 1214 665 778 231 177 86 323 328 1073 153 694 851 147 1 24 186 1
Below cutoff 959 1552 563 326 785 315 3076 1727 649 39 493 594 19 709 2173 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001247987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_020826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047427339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB037848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC103681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC103736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ303362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL512743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP251101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W45345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000020926   ⟹   ENSP00000020926
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1145,240,302 - 45,286,341 (-)Ensembl
RefSeq Acc Id: ENST00000528101   ⟹   ENSP00000432975
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1145,252,589 - 45,285,924 (-)Ensembl
RefSeq Acc Id: ENST00000533332   ⟹   ENSP00000434967
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1145,243,701 - 45,286,067 (-)Ensembl
RefSeq Acc Id: NM_001247987   ⟹   NP_001234916
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381145,240,302 - 45,286,341 (-)NCBI
GRCh371145,261,853 - 45,307,884 (-)NCBI
HuRef1144,971,578 - 45,017,603 (-)NCBI
CHM1_11145,260,943 - 45,306,976 (-)NCBI
T2T-CHM13v2.01145,397,823 - 45,443,869 (-)NCBI
Sequence:
RefSeq Acc Id: NM_020826   ⟹   NP_065877
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381145,240,302 - 45,286,341 (-)NCBI
GRCh371145,261,853 - 45,307,884 (-)RGD
Build 361145,218,429 - 45,264,383 (-)NCBI Archive
Celera1145,409,536 - 45,455,569 (-)RGD
HuRef1144,971,578 - 45,017,603 (-)ENTREZGENE
CHM1_11145,260,943 - 45,306,976 (-)NCBI
T2T-CHM13v2.01145,397,823 - 45,443,869 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047427338   ⟹   XP_047283294
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381145,240,302 - 45,258,445 (-)NCBI
RefSeq Acc Id: XM_047427339   ⟹   XP_047283295
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381145,240,302 - 45,274,911 (-)NCBI
RefSeq Acc Id: XM_054369488   ⟹   XP_054225463
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01145,397,823 - 45,415,970 (-)NCBI
RefSeq Acc Id: XM_054369489   ⟹   XP_054225464
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01145,397,823 - 45,432,439 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_065877   ⟸   NM_020826
- Peptide Label: isoform 1
- UniProtKB: Q9H041 (UniProtKB/Swiss-Prot),   Q9BQS3 (UniProtKB/Swiss-Prot),   D3DQP1 (UniProtKB/Swiss-Prot),   A8K4P4 (UniProtKB/Swiss-Prot),   Q9P2C0 (UniProtKB/Swiss-Prot),   Q7L8C5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001234916   ⟸   NM_001247987
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: ENSP00000434967   ⟸   ENST00000533332
RefSeq Acc Id: ENSP00000020926   ⟸   ENST00000020926
RefSeq Acc Id: ENSP00000432975   ⟸   ENST00000528101
RefSeq Acc Id: XP_047283295   ⟸   XM_047427339
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047283294   ⟸   XM_047427338
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054225464   ⟸   XM_054369489
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054225463   ⟸   XM_054369488
- Peptide Label: isoform X1
Protein Domains
C2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7L8C5-F1-model_v2 AlphaFold Q7L8C5 1-426 view protein structure

Promoters
RGD ID:7220139
Promoter ID:EPDNEW_H15815
Type:initiation region
Name:SYT13_1
Description:synaptotagmin 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381145,286,333 - 45,286,393EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14962 AgrOrtholog
COSMIC SYT13 COSMIC
Ensembl Genes ENSG00000019505 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000020926 ENTREZGENE
  ENST00000020926.8 UniProtKB/Swiss-Prot
  ENST00000528101.1 UniProtKB/TrEMBL
  ENST00000533332.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000019505 GTEx
HGNC ID HGNC:14962 ENTREZGENE
Human Proteome Map SYT13 Human Proteome Map
InterPro C2_dom UniProtKB/Swiss-Prot
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SYT13 UniProtKB/Swiss-Prot
KEGG Report hsa:57586 UniProtKB/Swiss-Prot
NCBI Gene 57586 ENTREZGENE
OMIM 607716 OMIM
PANTHER PTHR10024:SF250 UniProtKB/Swiss-Prot
  SYNAPTOTAGMIN UniProtKB/Swiss-Prot
Pfam PF00168 UniProtKB/Swiss-Prot
PharmGKB PA37942 PharmGKB
PROSITE PS50004 UniProtKB/Swiss-Prot
SMART SM00239 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K4P4 ENTREZGENE
  D3DQP1 ENTREZGENE
  H0YD47_HUMAN UniProtKB/TrEMBL
  H0YE47_HUMAN UniProtKB/TrEMBL
  Q7L8C5 ENTREZGENE
  Q9BQS3 ENTREZGENE
  Q9H041 ENTREZGENE
  Q9P2C0 ENTREZGENE
  SYT13_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A8K4P4 UniProtKB/Swiss-Prot
  D3DQP1 UniProtKB/Swiss-Prot
  Q9BQS3 UniProtKB/Swiss-Prot
  Q9H041 UniProtKB/Swiss-Prot
  Q9P2C0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 SYT13  synaptotagmin 13    synaptotagmin XIII  Symbol and/or name change 5135510 APPROVED