ZBTB11-AS1 (ZBTB11 antisense RNA 1) - Rat Genome Database

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Gene: ZBTB11-AS1 (ZBTB11 antisense RNA 1) Homo sapiens
Analyze
Symbol: ZBTB11-AS1
Name: ZBTB11 antisense RNA 1
RGD ID: 7249450
HGNC Page HGNC:48573
Description: ASSOCIATED WITH autosomal recessive intellectual developmental disorder 69; INTERACTS WITH acrylamide; aristolochic acid A; methotrexate
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383101,676,430 - 101,679,217 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3101,676,424 - 101,679,217 (+)EnsemblGRCh38hg38GRCh38
GRCh373101,395,274 - 101,398,061 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera399,788,381 - 99,791,168 (+)NCBICelera
Cytogenetic Map3q12.3NCBI
HuRef398,764,434 - 98,767,221 (+)NCBIHuRef
CHM1_13101,358,577 - 101,361,364 (+)NCBICHM1_1
T2T-CHM13v2.03104,389,040 - 104,391,827 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11181995   PMID:12477932   PMID:14702039   PMID:15489334   PMID:35576477  


Genomics

Variants

.
Variants in ZBTB11-AS1
10 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_014415.3(ZBTB11):c.382C>T (p.Pro128Ser) single nucleotide variant Malignant melanoma [RCV000060642] Chr3:101672142 [GRCh38]
Chr3:101390986 [GRCh37]
Chr3:102873676 [NCBI36]
Chr3:3q12.3		 not provided
GRCh38/hg38 3q12.3(chr3:101596165-102374145)x3 copy number gain See cases [RCV000134705] Chr3:101596165..102374145 [GRCh38]
Chr3:101315009..102092989 [GRCh37]
Chr3:102797699..103575679 [NCBI36]
Chr3:3q12.3		 likely benign
GRCh38/hg38 3q11.1-13.31(chr3:93819623-116887056)x1 copy number loss See cases [RCV000135320] Chr3:93819623..116887056 [GRCh38]
Chr3:93538467..116605903 [GRCh37]
Chr3:95021157..118088593 [NCBI36]
Chr3:3q11.1-13.31		 pathogenic
GRCh38/hg38 3q11.2-13.31(chr3:97795369-115663349)x1 copy number loss See cases [RCV000138186] Chr3:97795369..115663349 [GRCh38]
Chr3:97514213..115382196 [GRCh37]
Chr3:98996903..116864886 [NCBI36]
Chr3:3q11.2-13.31		 pathogenic|uncertain significance
GRCh38/hg38 3q12.3(chr3:101626311-101744959)x3 copy number gain See cases [RCV000141405] Chr3:101626311..101744959 [GRCh38]
Chr3:101345155..101463803 [GRCh37]
Chr3:102827845..102946493 [NCBI36]
Chr3:3q12.3		 uncertain significance
GRCh38/hg38 3q11.1-24(chr3:93800620-145695381)x3 copy number gain See cases [RCV000142340] Chr3:93800620..145695381 [GRCh38]
Chr3:93519464..145413168 [GRCh37]
Chr3:95002154..146895858 [NCBI36]
Chr3:3q11.1-24		 pathogenic
GRCh38/hg38 3q11.1-13.11(chr3:93819623-103888749)x3 copy number gain See cases [RCV000143259] Chr3:93819623..103888749 [GRCh38]
Chr3:93538467..103607593 [GRCh37]
Chr3:95021157..105090283 [NCBI36]
Chr3:3q11.1-13.11		 likely pathogenic|uncertain significance
GRCh38/hg38 3q11.1-21.1(chr3:93886671-123216683)x1 copy number loss See cases [RCV000051543] Chr3:93886671..123216683 [GRCh38]
Chr3:93605515..122935530 [GRCh37]
Chr3:95088205..124418220 [NCBI36]
Chr3:3q11.1-21.1		 pathogenic
NM_014415.4(ZBTB11):c.154C>T (p.Arg52Trp) single nucleotide variant Intellectual developmental disorder, autosomal recessive 69 [RCV002280849] Chr3:101676761 [GRCh38]
Chr3:101395605 [GRCh37]
Chr3:3q12.3		 pathogenic
NM_014415.4(ZBTB11):c.13G>A (p.Glu5Lys) single nucleotide variant not provided [RCV002275797] Chr3:101676902 [GRCh38]
Chr3:101395746 [GRCh37]
Chr3:3q12.3		 uncertain significance
NM_014415.4(ZBTB11):c.271C>T (p.Gln91Ter) single nucleotide variant not provided [RCV002276295] Chr3:101676644 [GRCh38]
Chr3:101395488 [GRCh37]
Chr3:3q12.3		 uncertain significance
NM_014415.4(ZBTB11):c.85_97del (p.Val29fs) deletion Intellectual developmental disorder, autosomal recessive 69 [RCV003234937] Chr3:101676818..101676830 [GRCh38]
Chr3:101395662..101395674 [GRCh37]
Chr3:3q12.3		 pathogenic
NM_014415.4(ZBTB11):c.166C>T (p.Arg56Cys) single nucleotide variant not specified [RCV004116519] Chr3:101676749 [GRCh38]
Chr3:101395593 [GRCh37]
Chr3:3q12.3		 uncertain significance
NM_014415.4(ZBTB11):c.17G>A (p.Ser6Asn) single nucleotide variant not specified [RCV004148849] Chr3:101676898 [GRCh38]
Chr3:101395742 [GRCh37]
Chr3:3q12.3		 uncertain significance
NM_014415.4(ZBTB11):c.282C>A (p.His94Gln) single nucleotide variant not specified [RCV004173200] Chr3:101676633 [GRCh38]
Chr3:101395477 [GRCh37]
Chr3:3q12.3		 uncertain significance
NM_014415.4(ZBTB11):c.280C>T (p.His94Tyr) single nucleotide variant not specified [RCV004084394] Chr3:101676635 [GRCh38]
Chr3:101395479 [GRCh37]
Chr3:3q12.3		 uncertain significance
NM_014415.4(ZBTB11):c.118T>C (p.Tyr40His) single nucleotide variant not specified [RCV004221853] Chr3:101676797 [GRCh38]
Chr3:101395641 [GRCh37]
Chr3:3q12.3		 uncertain significance
NM_014415.4(ZBTB11):c.35G>C (p.Arg12Pro) single nucleotide variant not specified [RCV004131610] Chr3:101676880 [GRCh38]
Chr3:101395724 [GRCh37]
Chr3:3q12.3		 uncertain significance
GRCh38/hg38 3q11.1-21.2(chr3:93979547-124774010)x1 copy number loss Chromosome 3q13.31 deletion syndrome [RCV003327614] Chr3:93979547..124774010 [GRCh38]
Chr3:3q11.1-21.2		 pathogenic
NM_014415.4(ZBTB11):c.219C>T (p.Asp73=) single nucleotide variant ZBTB11-related condition [RCV003972020] Chr3:101676696 [GRCh38]
Chr3:101395540 [GRCh37]
Chr3:3q12.3		 likely benign
NM_014415.4(ZBTB11):c.220C>A (p.Leu74Ile) single nucleotide variant not specified [RCV004478759] Chr3:101676695 [GRCh38]
Chr3:101395539 [GRCh37]
Chr3:3q12.3		 uncertain significance
NM_014415.4(ZBTB11):c.253A>G (p.Thr85Ala) single nucleotide variant not specified [RCV004478762] Chr3:101676662 [GRCh38]
Chr3:101395506 [GRCh37]
Chr3:3q12.3		 uncertain significance
NM_014415.4(ZBTB11):c.11A>G (p.Glu4Gly) single nucleotide variant not specified [RCV004478752] Chr3:101676904 [GRCh38]
Chr3:101395748 [GRCh37]
Chr3:3q12.3		 uncertain significance
NM_014415.4(ZBTB11):c.167G>A (p.Arg56His) single nucleotide variant not specified [RCV004478757] Chr3:101676748 [GRCh38]
Chr3:101395592 [GRCh37]
Chr3:3q12.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:305
Count of miRNA genes:270
Interacting mature miRNAs:295
Transcripts:ENST00000536865, ENST00000609682
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D8S2078  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37642,922,916 - 42,923,048UniSTSGRCh37
GRCh373101,397,860 - 101,397,992UniSTSGRCh37
Build 363102,880,550 - 102,880,682RGDNCBI36
Celera399,790,967 - 99,791,099RGD
Celera644,475,181 - 44,475,313UniSTS
Cytogenetic Map3q12.3UniSTS
HuRef398,767,020 - 98,767,152UniSTS
HuRef642,640,249 - 42,640,381UniSTS
sY3084  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map21q22.12UniSTS
Cytogenetic Map15q13UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map6q22.33UniSTS
Cytogenetic Map1q12UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map7q11.2UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map11q14UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map18q22.1UniSTS
Cytogenetic Map10p15.3UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map2q33-q34UniSTS
Cytogenetic Map12q21.33UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map3q25UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map12p12.1UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map1q42.11UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map4q27UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map18q12.1-q21.1UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map14q22UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map12q21.1UniSTS
Cytogenetic Map1p35.3-p33UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map14q24UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map5q15UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map7p22UniSTS
Cytogenetic Map15q15-q21.1UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map18p11.3-p11.2UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map6p22.3-p22.1UniSTS
Cytogenetic Map10q22.3UniSTS
Cytogenetic Map1p36.11-p34.2UniSTS
Cytogenetic Map7q32.1UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic MapXq13.2UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map1q42.1-q43UniSTS
Cytogenetic Map7q31UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map9p24.1UniSTS
Cytogenetic Map3q13.33UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic Map11p15UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map6q27UniSTS
Cytogenetic Map22q13.31UniSTS
Cytogenetic Map10q11.22UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map13q13.3UniSTS
Cytogenetic Map18q23UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map15q13.3UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapXq21.3UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic MapXq12UniSTS
Cytogenetic Map20p11UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map5p12UniSTS
Cytogenetic Map1p36.22UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map4p16UniSTS
Cytogenetic Map6q16.1UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map18p11.22UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map9q31.3UniSTS
Cytogenetic Map1q22-q23UniSTS
Cytogenetic Map13q32.1UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map22q13.1-q13.2UniSTS
Cytogenetic Map7p15UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map5p15.33UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map15q26.2UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map8q13UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map1p22.2UniSTS
Cytogenetic Map2q12UniSTS
Cytogenetic Map3q21.1UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map14q32.1UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map1p36.3UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map7p21.3UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map4q32UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map9p12UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map6q16.2UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map3q12.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 5 1 7 11 7 3 2 45 18
Low 2420 2606 1678 577 1643 419 4250 2013 3503 415 1403 1590 170 1204 2694 4
Below cutoff 7 373 45 45 293 45 94 173 202 1 94

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000609682
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3101,676,424 - 101,679,217 (+)Ensembl
RefSeq Acc Id: NR_024407
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,676,430 - 101,679,217 (+)NCBI
GRCh373101,395,274 - 101,398,061 (+)NCBI
HuRef398,764,434 - 98,767,221 (+)NCBI
CHM1_13101,358,577 - 101,361,364 (+)NCBI
T2T-CHM13v2.03104,389,040 - 104,391,827 (+)NCBI
Sequence:
Protein Sequences
GenBank Protein EAW79785 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences

Promoters
RGD ID:15095635
Promoter ID:EPDNEWNC_H472
Type:initiation region
Name:ZBTB11-AS1_1
Description:ZBTB11 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48573]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,676,468 - 101,676,528EPDNEWNC

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:48573 AgrOrtholog
COSMIC ZBTB11-AS1 COSMIC
Ensembl Genes ENSG00000256628 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000609682 ENTREZGENE
GTEx ENSG00000256628 GTEx
HGNC ID HGNC:48573 ENTREZGENE
Human Proteome Map ZBTB11-AS1 Human Proteome Map
NCBI Gene ZBTB11-AS1 ENTREZGENE
RNAcentral URS0000759C0C RNACentral