LINC00943 (long intergenic non-protein coding RNA 943) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: LINC00943 (long intergenic non-protein coding RNA 943) Homo sapiens
Analyze
Symbol: LINC00943
Name: long intergenic non-protein coding RNA 943
RGD ID: 7245167
HGNC Page HGNC:48639
Description: INTERACTS WITH berberine; N-methyl-4-phenylpyridinium
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: RP11-173C20.1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812126,737,007 - 126,746,256 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12126,723,412 - 126,749,027 (+)EnsemblGRCh38hg38GRCh38
GRCh3712127,221,553 - 127,230,802 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map12q24.32NCBI
HuRef12124,190,919 - 124,200,168 (+)NCBIHuRef
CHM1_112127,041,874 - 127,051,123 (+)NCBICHM1_1
T2T-CHM13v2.012126,744,595 - 126,753,846 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:32993558   PMID:33208053   PMID:38145786   PMID:38627774  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12q24.31-24.33(chr12:123509825-133191400)x3 copy number gain See cases [RCV000135535] Chr12:123509825..133191400 [GRCh38]
Chr12:123994372..133767986 [GRCh37]
Chr12:122560325..132278059 [NCBI36]
Chr12:12q24.31-24.33
pathogenic
GRCh38/hg38 12q24.32(chr12:126587447-127900558)x3 copy number gain See cases [RCV000136703] Chr12:126587447..127900558 [GRCh38]
Chr12:127071993..128385103 [GRCh37]
Chr12:125637946..126951056 [NCBI36]
Chr12:12q24.32
uncertain significance
GRCh38/hg38 12q24.31-24.33(chr12:120697672-133202490)x3 copy number gain See cases [RCV000137651] Chr12:120697672..133202490 [GRCh38]
Chr12:121135475..133779076 [GRCh37]
Chr12:119619858..132289149 [NCBI36]
Chr12:12q24.31-24.33
pathogenic
GRCh38/hg38 12q24.32(chr12:126309824-127076515)x3 copy number gain See cases [RCV000137660] Chr12:126309824..127076515 [GRCh38]
Chr12:126794370..127561060 [GRCh37]
Chr12:125360323..126127013 [NCBI36]
Chr12:12q24.32
likely benign
GRCh38/hg38 12q24.32(chr12:126526398-127998599)x3 copy number gain See cases [RCV000139449] Chr12:126526398..127998599 [GRCh38]
Chr12:127010944..128483144 [GRCh37]
Chr12:125576897..127049097 [NCBI36]
Chr12:12q24.32
uncertain significance|conflicting data from submitters
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh38/hg38 12q24.31-24.32(chr12:120718786-127500215)x1 copy number loss See cases [RCV000142454] Chr12:120718786..127500215 [GRCh38]
Chr12:121156589..127984760 [GRCh37]
Chr12:119640972..126550713 [NCBI36]
Chr12:12q24.31-24.32
pathogenic
GRCh38/hg38 12q24.32(chr12:125862809-127788730)x3 copy number gain See cases [RCV000142216] Chr12:125862809..127788730 [GRCh38]
Chr12:126347355..128273275 [GRCh37]
Chr12:124913308..126839228 [NCBI36]
Chr12:12q24.32
uncertain significance
GRCh38/hg38 12q24.31-24.32(chr12:121917758-127802717)x1 copy number loss See cases [RCV000143250] Chr12:121917758..127802717 [GRCh38]
Chr12:122355664..128287262 [GRCh37]
Chr12:120840047..126853215 [NCBI36]
Chr12:12q24.31-24.32
pathogenic
GRCh38/hg38 12q24.21-24.33(chr12:114268403-133201316)x3 copy number gain See cases [RCV000143656] Chr12:114268403..133201316 [GRCh38]
Chr12:114706208..133777902 [GRCh37]
Chr12:113190591..132287975 [NCBI36]
Chr12:12q24.21-24.33
pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:122985202-130714574)x1 copy number loss See cases [RCV000051345] Chr12:122985202..130714574 [GRCh38]
Chr12:123469749..131199119 [GRCh37]
Chr12:122035702..129765072 [NCBI36]
Chr12:12q24.31-24.33
pathogenic
GRCh38/hg38 12q24.23-24.33(chr12:118165459-133182322)x3 copy number gain See cases [RCV000050866] Chr12:118165459..133182322 [GRCh38]
Chr12:118603264..133758908 [GRCh37]
Chr12:117087647..132268981 [NCBI36]
Chr12:12q24.23-24.33
pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123444758-133191400)x3 copy number gain See cases [RCV000051151] Chr12:123444758..133191400 [GRCh38]
Chr12:123929305..133767986 [GRCh37]
Chr12:122495258..132278059 [NCBI36]
Chr12:12q24.31-24.33
pathogenic
GRCh38/hg38 12q24.21-24.33(chr12:115131583-133166920)x3 copy number gain See cases [RCV000053689] Chr12:115131583..133166920 [GRCh38]
Chr12:115569388..133743506 [GRCh37]
Chr12:114053771..132253579 [NCBI36]
Chr12:12q24.21-24.33
pathogenic
GRCh38/hg38 12q24.23-24.33(chr12:119417382-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|See cases [RCV000053691] Chr12:119417382..133191400 [GRCh38]
Chr12:119855187..133767986 [GRCh37]
Chr12:118339570..132278059 [NCBI36]
Chr12:12q24.23-24.33
pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123365769-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|See cases [RCV000053693] Chr12:123365769..133191400 [GRCh38]
Chr12:123850316..133767986 [GRCh37]
Chr12:122416269..132278059 [NCBI36]
Chr12:12q24.31-24.33
pathogenic
GRCh38/hg38 12q24.32-24.33(chr12:126403612-133166920)x3 copy number gain See cases [RCV000053715] Chr12:126403612..133166920 [GRCh38]
Chr12:126888158..133743506 [GRCh37]
Chr12:125454111..132253579 [NCBI36]
Chr12:12q24.32-24.33
pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:708
Count of miRNA genes:339
Interacting mature miRNAs:368
Transcripts:ENST00000345111, ENST00000535118, ENST00000535544, ENST00000537374, ENST00000539315, ENST00000540250, ENST00000541359
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D12S307  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712127,216,405 - 127,216,555UniSTSGRCh37
GRCh3712127,216,393 - 127,216,553UniSTSGRCh37
Build 3612125,782,358 - 125,782,508RGDNCBI36
Celera12126,821,752 - 126,821,890RGD
Celera12126,821,740 - 126,821,888UniSTS
Cytogenetic Map12q24.32UniSTS
HuRef12124,185,783 - 124,185,921UniSTS
HuRef12124,185,771 - 124,185,919UniSTS
Marshfield Genetic Map12148.24RGD
Genethon Genetic Map12149.5UniSTS
deCODE Assembly Map12149.78UniSTS
Stanford-G3 RH Map125412.0UniSTS
Whitehead-YAC Contig Map12 UniSTS
GeneMap99-G3 RH Map125358.0UniSTS
RH92779  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712127,229,644 - 127,229,773UniSTSGRCh37
Build 3612125,795,597 - 125,795,726RGDNCBI36
Celera12126,834,979 - 126,835,108RGD
Cytogenetic Map12q24.32UniSTS
HuRef12124,199,010 - 124,199,139UniSTS
GeneMap99-GB4 RH Map12488.12UniSTS
RH92063  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712127,230,509 - 127,230,639UniSTSGRCh37
Build 3612125,796,462 - 125,796,592RGDNCBI36
Celera12126,835,844 - 126,835,974RGD
Cytogenetic Map12q24.32UniSTS
HuRef12124,199,875 - 124,200,005UniSTS
GeneMap99-GB4 RH Map12487.6UniSTS
D12S307  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12q24.32UniSTS
Marshfield Genetic Map12148.24UniSTS
Genethon Genetic Map12149.5UniSTS
deCODE Assembly Map12149.78UniSTS
Whitehead-YAC Contig Map12 UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium 4 5 342
Low 111 71 54 10 439 11 29 5 922 30 87 148 5 12 8
Below cutoff 1836 1934 1220 427 1074 272 2934 1448 2080 190 743 1214 157 1057 1920

Sequence


RefSeq Acc Id: ENST00000345111
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,742,736 - 126,746,236 (+)Ensembl
RefSeq Acc Id: ENST00000535118
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,007 - 126,745,336 (+)Ensembl
RefSeq Acc Id: ENST00000535544
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,741,665 - 126,746,252 (+)Ensembl
RefSeq Acc Id: ENST00000537374
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,726,270 - 126,745,326 (+)Ensembl
RefSeq Acc Id: ENST00000539315
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,726,600 - 126,745,528 (+)Ensembl
RefSeq Acc Id: ENST00000540250
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,734,909 - 126,745,332 (+)Ensembl
RefSeq Acc Id: ENST00000541359
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,742,150 - 126,745,332 (+)Ensembl
RefSeq Acc Id: ENST00000616373
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,744,769 - 126,745,326 (+)Ensembl
RefSeq Acc Id: ENST00000653920
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,726,265 - 126,746,255 (+)Ensembl
RefSeq Acc Id: ENST00000654123
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,025 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000654173
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,046 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000654558
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,741,419 - 126,745,332 (+)Ensembl
RefSeq Acc Id: ENST00000655433
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,007 - 126,745,336 (+)Ensembl
RefSeq Acc Id: ENST00000656138
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,726,562 - 126,749,027 (+)Ensembl
RefSeq Acc Id: ENST00000656166
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,046 - 126,740,460 (+)Ensembl
RefSeq Acc Id: ENST00000656659
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,025 - 126,745,332 (+)Ensembl
RefSeq Acc Id: ENST00000656695
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,053 - 126,746,905 (+)Ensembl
RefSeq Acc Id: ENST00000658458
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,723,416 - 126,746,905 (+)Ensembl
RefSeq Acc Id: ENST00000659292
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,013 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000659340
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,736,998 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000659485
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,053 - 126,745,320 (+)Ensembl
RefSeq Acc Id: ENST00000659587
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,736,998 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000660082
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,003 - 126,745,336 (+)Ensembl
RefSeq Acc Id: ENST00000660396
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,053 - 126,745,332 (+)Ensembl
RefSeq Acc Id: ENST00000660709
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,025 - 126,745,336 (+)Ensembl
RefSeq Acc Id: ENST00000661264
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,726,483 - 126,746,237 (+)Ensembl
RefSeq Acc Id: ENST00000661435
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,007 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000661679
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,053 - 126,746,245 (+)Ensembl
RefSeq Acc Id: ENST00000662118
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,734,947 - 126,745,326 (+)Ensembl
RefSeq Acc Id: ENST00000662393
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,060 - 126,745,326 (+)Ensembl
RefSeq Acc Id: ENST00000662520
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,025 - 126,746,914 (+)Ensembl
RefSeq Acc Id: ENST00000663365
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,051 - 126,745,325 (+)Ensembl
RefSeq Acc Id: ENST00000663771
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,736,980 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000664572
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,051 - 126,745,326 (+)Ensembl
RefSeq Acc Id: ENST00000665222
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,735,181 - 126,745,326 (+)Ensembl
RefSeq Acc Id: ENST00000665596
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,053 - 126,746,916 (+)Ensembl
RefSeq Acc Id: ENST00000665641
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,736,986 - 126,745,332 (+)Ensembl
RefSeq Acc Id: ENST00000665789
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,025 - 126,745,332 (+)Ensembl
RefSeq Acc Id: ENST00000665976
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,726,230 - 126,746,229 (+)Ensembl
RefSeq Acc Id: ENST00000665993
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,726,512 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000666484
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,091 - 126,745,332 (+)Ensembl
RefSeq Acc Id: ENST00000667256
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,723,412 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000667312
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,723,416 - 126,745,326 (+)Ensembl
RefSeq Acc Id: ENST00000667375
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,051 - 126,745,326 (+)Ensembl
RefSeq Acc Id: ENST00000667490
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,736,980 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000668231
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,013 - 126,746,225 (+)Ensembl
RefSeq Acc Id: ENST00000668611
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,025 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000669031
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,053 - 126,747,267 (+)Ensembl
RefSeq Acc Id: ENST00000669417
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,007 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000669542
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,022 - 126,746,256 (+)Ensembl
RefSeq Acc Id: ENST00000670225
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,723,424 - 126,745,326 (+)Ensembl
RefSeq Acc Id: ENST00000670324
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,734,966 - 126,745,332 (+)Ensembl
RefSeq Acc Id: ENST00000670760
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12126,737,019 - 126,746,256 (+)Ensembl
RefSeq Acc Id: NR_038256
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812126,737,007 - 126,746,256 (+)NCBI
GRCh3712127,221,553 - 127,230,802 (+)NCBI
HuRef12124,190,919 - 124,200,168 (+)NCBI
CHM1_112127,041,874 - 127,051,123 (+)NCBI
T2T-CHM13v2.012126,744,595 - 126,753,846 (+)NCBI
Sequence:
Protein Sequences
GenBank Protein AAL65262 (Get FASTA)   NCBI Sequence Viewer  

Promoters
RGD ID:15096680
Promoter ID:EPDNEWNC_H1511
Type:initiation region
Name:LINC00943_2
Description:long intergenic non-protein coding RNA 943 [Source:HGNCSymbol;Acc:HGNC:48639]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812126,737,053 - 126,737,113EPDNEWNC

Additional Information

Database Acc Id Source(s)
COSMIC LINC00943 COSMIC
Ensembl Genes ENSG00000189238 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000659340 ENTREZGENE
GTEx ENSG00000189238 GTEx
HGNC ID HGNC:48639 ENTREZGENE
Human Proteome Map LINC00943 Human Proteome Map
NCBI Gene LINC00943 ENTREZGENE
RNAcentral URS000075E332 RNACentral