LINC00845 (long intergenic non-protein coding RNA 845) - Rat Genome Database

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Gene: LINC00845 (long intergenic non-protein coding RNA 845) Homo sapiens
Analyze
Symbol: LINC00845
Name: long intergenic non-protein coding RNA 845
RGD ID: 7206996
HGNC Page HGNC:45033
Description: ASSOCIATED WITH Autosomal Dominant Intellectual Developmental Disorder 70
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381061,016,275 - 61,026,417 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1061,001,088 - 61,194,727 (+)EnsemblGRCh38hg38GRCh38
GRCh371062,776,033 - 62,786,175 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map10q21.2NCBI
HuRef1056,765,113 - 56,775,256 (+)NCBIHuRef
CHM1_11063,058,236 - 63,068,379 (+)NCBICHM1_1
T2T-CHM13v2.01061,873,037 - 61,883,179 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q11.21-22.2(chr10:42685306-73715908)x3 copy number gain See cases [RCV000134848] Chr10:42685306..73715908 [GRCh38]
Chr10:43180754..75475666 [GRCh37]
Chr10:42500760..75145672 [NCBI36]
Chr10:10q11.21-22.2		 pathogenic
GRCh38/hg38 10q11.23-23.2(chr10:50729367-87147204)x3 copy number gain See cases [RCV000138007] Chr10:50729367..87147204 [GRCh38]
Chr10:52489127..88906961 [GRCh37]
Chr10:52159133..88896941 [NCBI36]
Chr10:10q11.23-23.2		 pathogenic
GRCh38/hg38 10q21.1-21.3(chr10:55287177-67558442)x3 copy number gain See cases [RCV000141179] Chr10:55287177..67558442 [GRCh38]
Chr10:57046937..69318200 [GRCh37]
Chr10:56716943..68988206 [NCBI36]
Chr10:10q21.1-21.3		 pathogenic
GRCh38/hg38 10q11.21-21.3(chr10:42112187-67400675)x3 copy number gain See cases [RCV000142967] Chr10:42112187..67400675 [GRCh38]
Chr10:42607635..69160433 [GRCh37]
Chr10:41927641..68830439 [NCBI36]
Chr10:10q11.21-21.3		 pathogenic
GRCh38/hg38 10q21.2-21.3(chr10:60977777-62913465)x3 copy number gain See cases [RCV000143288] Chr10:60977777..62913465 [GRCh38]
Chr10:62737535..64673225 [GRCh37]
Chr10:62407541..64343231 [NCBI36]
Chr10:10q21.2-21.3		 uncertain significance
GRCh38/hg38 10q21.1-22.2(chr10:58436466-74415216)x1 copy number loss See cases [RCV000052511] Chr10:58436466..74415216 [GRCh38]
Chr10:60196226..76174974 [GRCh37]
Chr10:59866232..75844980 [NCBI36]
Chr10:10q21.1-22.2		 pathogenic
NC_000010.11:g.(?_59792917)_(68231677_?)del deletion Intellectual developmental disorder, autosomal dominant 70 [RCV003883491] Chr10:59792917..68231677 [GRCh38]
Chr10:10q21.2-21.3		 likely pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:75
Interacting mature miRNAs:76
Transcripts:ENST00000417931
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium
Low 10 10 1 10 13 104 37 1
Below cutoff 131 37 137 66 23 66 157 131 790 120 353 59 1 22 122 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000417931
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1061,016,275 - 61,026,420 (+)Ensembl
RefSeq Acc Id: ENST00000686519
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1061,001,117 - 61,027,604 (+)Ensembl
RefSeq Acc Id: ENST00000687498
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1061,001,088 - 61,194,727 (+)Ensembl
RefSeq Acc Id: NR_108052
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381061,016,275 - 61,026,417 (+)NCBI
HuRef1056,765,113 - 56,775,256 (+)NCBI
CHM1_11063,058,236 - 63,068,379 (+)NCBI
T2T-CHM13v2.01061,873,037 - 61,883,179 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC LINC00845 COSMIC
Ensembl Genes ENSG00000227244 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000417931 ENTREZGENE
GTEx ENSG00000227244 GTEx
HGNC ID HGNC:45033 ENTREZGENE
Human Proteome Map LINC00845 Human Proteome Map
NCBI Gene LINC00845 ENTREZGENE
RNAcentral URS000075A6F8 RNACentral