DCTN1-AS1 (DCTN1 antisense RNA 1) - Rat Genome Database

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Gene: DCTN1-AS1 (DCTN1 antisense RNA 1) Homo sapiens
Analyze
Symbol: DCTN1-AS1
Name: DCTN1 antisense RNA 1
RGD ID: 6770566
HGNC Page HGNC:44151
Description: INTERACTS WITH nickel atom
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: AC005041.9
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38274,385,503 - 74,398,668 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl274,385,474 - 74,393,882 (+)EnsemblGRCh38hg38GRCh38
GRCh37274,612,630 - 74,625,795 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera274,444,035 - 74,452,198 (+)NCBICelera
Cytogenetic Map2p13.1NCBI
HuRef274,349,158 - 74,357,321 (+)NCBIHuRef
CHM1_1274,542,272 - 74,550,435 (+)NCBICHM1_1
T2T-CHM13v2.0274,394,062 - 74,407,241 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
nickel atom  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Variants

.
Variants in DCTN1-AS1
1 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2p16.1-11.2(chr2:58279519-83586962)x3 copy number gain See cases [RCV000136053] Chr2:58279519..83586962 [GRCh38]
Chr2:58506654..83814086 [GRCh37]
Chr2:58360158..83667597 [NCBI36]
Chr2:2p16.1-11.2		 pathogenic
GRCh38/hg38 2p16.3-11.2(chr2:47620388-86702722)x3 copy number gain See cases [RCV000137586] Chr2:47620388..86702722 [GRCh38]
Chr2:47847527..86929845 [GRCh37]
Chr2:47701031..86783356 [NCBI36]
Chr2:2p16.3-11.2		 uncertain significance
GRCh38/hg38 2p25.1-11.2(chr2:7495123-87705899)x3 copy number gain See cases [RCV000141494] Chr2:7495123..87705899 [GRCh38]
Chr2:7635254..88005418 [GRCh37]
Chr2:7552705..87786533 [NCBI36]
Chr2:2p25.1-11.2		 benign
GRCh38/hg38 2p13.1-12(chr2:74375779-75517520)x1 copy number loss See cases [RCV000143456] Chr2:74375779..75517520 [GRCh38]
Chr2:74602906..75744646 [GRCh37]
Chr2:74456414..75598154 [NCBI36]
Chr2:2p13.1-12		 likely pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1042
Count of miRNA genes:655
Interacting mature miRNAs:749
Transcripts:ENST00000412957, ENST00000416630, ENST00000418990, ENST00000426715, ENST00000427343, ENST00000437991
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 1 105 1
Low 43 270 1 5 1 6 2 2655 8 264 33 1 1 2
Below cutoff 2159 1779 1003 318 1097 172 3096 1432 916 268 1003 1289 159 907 1851 3

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000412957
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl274,385,524 - 74,392,896 (+)Ensembl
RefSeq Acc Id: ENST00000416630
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl274,385,486 - 74,388,178 (+)Ensembl
RefSeq Acc Id: ENST00000418990
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl274,385,496 - 74,391,427 (+)Ensembl
RefSeq Acc Id: ENST00000426715
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl274,385,497 - 74,391,904 (+)Ensembl
RefSeq Acc Id: ENST00000427343
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl274,385,493 - 74,393,511 (+)Ensembl
RefSeq Acc Id: ENST00000437991
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl274,385,718 - 74,393,882 (+)Ensembl
RefSeq Acc Id: ENST00000664266
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl274,385,474 - 74,393,859 (+)Ensembl
RefSeq Acc Id: ENST00000664792
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl274,385,693 - 74,393,524 (+)Ensembl
RefSeq Acc Id: NR_024463
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38274,385,503 - 74,393,881 (+)NCBI
GRCh37274,612,845 - 74,621,008 (+)NCBI
HuRef274,349,158 - 74,357,321 (+)NCBI
CHM1_1274,542,272 - 74,550,435 (+)NCBI
T2T-CHM13v2.0274,394,062 - 74,402,454 (+)NCBI
Sequence:
RefSeq Acc Id: NR_158172
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38274,385,503 - 74,393,881 (+)NCBI
T2T-CHM13v2.0274,394,062 - 74,402,454 (+)NCBI
Sequence:
RefSeq Acc Id: NR_158173
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38274,385,503 - 74,393,881 (+)NCBI
T2T-CHM13v2.0274,394,062 - 74,402,454 (+)NCBI
Sequence:
RefSeq Acc Id: NR_158174
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38274,385,503 - 74,398,668 (+)NCBI
T2T-CHM13v2.0274,394,062 - 74,407,241 (+)NCBI
Sequence:
Promoters
RGD ID:15095454
Promoter ID:EPDNEWNC_H278
Type:initiation region
Name:DCTN1-AS1_1
Description:DCTN1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44151]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38274,385,509 - 74,385,569EPDNEWNC

Additional Information

Database Acc Id Source(s)
COSMIC DCTN1-AS1 COSMIC
Ensembl Genes ENSG00000237737 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000427343 ENTREZGENE
  ENST00000437991 ENTREZGENE
  ENST00000664266 ENTREZGENE
GTEx ENSG00000237737 GTEx
HGNC ID HGNC:44151 ENTREZGENE
Human Proteome Map DCTN1-AS1 Human Proteome Map
NCBI Gene DCTN1-AS1 ENTREZGENE
RNAcentral URS0000D77F4C RNACentral
  URS0000D77F6E RNACentral
  URS0000D78088 RNACentral
  URS0000D780AE RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-21 DCTN1-AS1  DCTN1 antisense RNA 1  DCTN1-AS1  DCTN1 antisense RNA 1 (non-protein coding)  Symbol and/or name change 5135510 APPROVED