TRABD2B (TraB domain containing 2B) - Rat Genome Database

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Gene: TRABD2B (TraB domain containing 2B) Homo sapiens
Analyze
Symbol: TRABD2B
Name: TraB domain containing 2B
RGD ID: 6770286
HGNC Page HGNC:44200
Description: Enables Wnt-protein binding activity and metalloendopeptidase activity. Involved in several processes, including negative regulation of Wnt signaling pathway; positive regulation of protein oxidation; and positive regulation of protein-containing complex assembly. Located in organelle membrane and plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: heart, kidney and adipose-enriched transmembrane protein homolog; metalloprotease TIKI2; RP11-543D5.2; TIKI2; TRAB domain-containing protein 2B; UPF0632 protein A
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38147,760,528 - 47,997,385 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl147,760,528 - 47,997,385 (-)EnsemblGRCh38hg38GRCh38
GRCh37148,226,200 - 48,463,057 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36148,003,896 - 48,235,839 (-)NCBINCBI36Build 36hg18NCBI36
Celera146,513,002 - 46,749,292 (-)NCBICelera
Cytogenetic Map1p33NCBI
HuRef146,343,095 - 46,579,167 (-)NCBIHuRef
CHM1_1148,343,333 - 48,579,625 (-)NCBICHM1_1
T2T-CHM13v2.0147,639,427 - 47,876,248 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
organelle membrane  (IBA,IDA)
plasma membrane  (IBA,IDA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16710414   PMID:20379614   PMID:21873635   PMID:22425255   PMID:22726442   PMID:23251661   PMID:23376485   PMID:24771064   PMID:25354456   PMID:26631728   PMID:26942462  


Genomics

Comparative Map Data
TRABD2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38147,760,528 - 47,997,385 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl147,760,528 - 47,997,385 (-)EnsemblGRCh38hg38GRCh38
GRCh37148,226,200 - 48,463,057 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36148,003,896 - 48,235,839 (-)NCBINCBI36Build 36hg18NCBI36
Celera146,513,002 - 46,749,292 (-)NCBICelera
Cytogenetic Map1p33NCBI
HuRef146,343,095 - 46,579,167 (-)NCBIHuRef
CHM1_1148,343,333 - 48,579,625 (-)NCBICHM1_1
T2T-CHM13v2.0147,639,427 - 47,876,248 (-)NCBIT2T-CHM13v2.0
Trabd2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394114,263,394 - 114,472,295 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4114,263,921 - 114,472,295 (+)EnsemblGRCm39 Ensembl
GRCm384114,406,682 - 114,615,098 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4114,406,724 - 114,615,098 (+)EnsemblGRCm38mm10GRCm38
MGSCv374114,079,329 - 114,287,703 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364113,904,620 - 114,108,672 (+)NCBIMGSCv36mm8
Celera4113,154,874 - 113,362,877 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map451.84NCBI
Trabd2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85133,178,014 - 133,395,740 (+)NCBIGRCr8
mRatBN7.25127,941,198 - 128,158,946 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5127,941,114 - 128,143,747 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05133,220,986 - 133,437,151 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5133,221,139 - 133,420,644 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05137,016,915 - 137,231,017 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45134,778,167 - 134,978,965 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5126,596,412 - 126,812,016 (+)NCBICelera
Cytogenetic Map5q35NCBI
Trabd2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546410,612,030 - 10,812,585 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546410,612,515 - 10,817,725 (+)NCBIChiLan1.0ChiLan1.0
TRABD2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21178,819,424 - 179,055,861 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11177,960,850 - 178,197,307 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0147,055,618 - 47,292,055 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1148,566,390 - 48,800,589 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl148,571,772 - 48,799,960 (-)Ensemblpanpan1.1panPan2
TRABD2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11512,778,537 - 12,987,316 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1512,771,859 - 12,996,357 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1512,927,212 - 13,140,334 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01512,923,781 - 13,136,795 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11512,726,485 - 12,936,858 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01512,793,616 - 13,007,008 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01512,863,380 - 13,074,058 (+)NCBIUU_Cfam_GSD_1.0
Trabd2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505862,706,640 - 62,927,944 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647428,531,931 - 28,752,736 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647428,565,563 - 28,752,370 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRABD2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6163,624,072 - 163,837,863 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16163,624,078 - 163,836,829 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26151,332,988 - 151,389,456 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRABD2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12084,932,091 - 85,162,560 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2084,932,721 - 85,157,167 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603331,928,461 - 32,158,401 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trabd2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248594,849,877 - 5,063,994 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248594,849,319 - 5,121,008 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TRABD2B
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001194986.1(TRABD2B):c.989-298T>C single nucleotide variant Lung cancer [RCV000090841] Chr1:47778842 [GRCh38]
Chr1:48244514 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.1(TRABD2B):c.667-40395G>T single nucleotide variant Lung cancer [RCV000090842] Chr1:47842014 [GRCh38]
Chr1:48307686 [GRCh37]
Chr1:1p33		 uncertain significance
GRCh37/hg19 1p36.12-12(chr1:20608823-120546301)x3 copy number loss not provided [RCV000762767] Chr1:20608823..120546301 [GRCh37]
Chr1:1p36.12-12		 likely benign
GRCh37/hg19 1p34.1-32.3(chr1:45303358-52157856)x1 copy number loss See cases [RCV000448358] Chr1:45303358..52157856 [GRCh37]
Chr1:1p34.1-32.3		 likely pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p33(chr1:48442182-48700325)x3 copy number gain not provided [RCV000736485] Chr1:48442182..48700325 [GRCh37]
Chr1:1p33		 benign
NM_001194986.2(TRABD2B):c.44C>T (p.Ala15Val) single nucleotide variant not specified [RCV004295764] Chr1:47996746 [GRCh38]
Chr1:48462418 [GRCh37]
Chr1:1p33		 uncertain significance
GRCh37/hg19 1p33-32.3(chr1:47272184-52505405)x1 copy number loss not provided [RCV001005086] Chr1:47272184..52505405 [GRCh37]
Chr1:1p33-32.3		 pathogenic
GRCh37/hg19 1p36.22-21.1(chr1:103343285-103455144)x3 copy number gain Global developmental delay [RCV000787285] Chr1:103343285..103455144 [GRCh37]
Chr1:1p36.22-21.1		 uncertain significance
GRCh37/hg19 1p33(chr1:48289410-49433953)x3 copy number gain not provided [RCV001259557] Chr1:48289410..49433953 [GRCh37]
Chr1:1p33		 uncertain significance
GRCh37/hg19 1p34.1-32.3(chr1:45303358-52157856) copy number loss not specified [RCV002053281] Chr1:45303358..52157856 [GRCh37]
Chr1:1p34.1-32.3		 likely pathogenic
NM_001194986.2(TRABD2B):c.149C>T (p.Pro50Leu) single nucleotide variant not specified [RCV004134729] Chr1:47994551 [GRCh38]
Chr1:48460223 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.284C>T (p.Ser95Leu) single nucleotide variant not specified [RCV004218638] Chr1:47994416 [GRCh38]
Chr1:48460088 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.1012G>A (p.Val338Ile) single nucleotide variant not specified [RCV004205268] Chr1:47778521 [GRCh38]
Chr1:48244193 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.10G>T (p.Ala4Ser) single nucleotide variant not specified [RCV004172087] Chr1:47996780 [GRCh38]
Chr1:48462452 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.1162G>A (p.Glu388Lys) single nucleotide variant not specified [RCV004124916] Chr1:47775357 [GRCh38]
Chr1:48241029 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.1268G>A (p.Arg423Gln) single nucleotide variant not specified [RCV004087736] Chr1:47775251 [GRCh38]
Chr1:48240923 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.424G>A (p.Gly142Ser) single nucleotide variant not specified [RCV004078106] Chr1:47994276 [GRCh38]
Chr1:48459948 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.496G>A (p.Val166Met) single nucleotide variant not specified [RCV004273424] Chr1:47994204 [GRCh38]
Chr1:48459876 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.985G>A (p.Ala329Thr) single nucleotide variant not specified [RCV004272028] Chr1:47794589 [GRCh38]
Chr1:48260261 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.433C>T (p.Leu145Phe) single nucleotide variant not specified [RCV004264635] Chr1:47994267 [GRCh38]
Chr1:48459939 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.1142C>T (p.Thr381Ile) single nucleotide variant not specified [RCV004266284] Chr1:47775377 [GRCh38]
Chr1:48241049 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.1091A>G (p.Gln364Arg) single nucleotide variant not specified [RCV004316132] Chr1:47775428 [GRCh38]
Chr1:48241100 [GRCh37]
Chr1:1p33		 likely benign
NM_001194986.2(TRABD2B):c.1198G>A (p.Asp400Asn) single nucleotide variant not specified [RCV004339293] Chr1:47775321 [GRCh38]
Chr1:48240993 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.242G>A (p.Arg81His) single nucleotide variant not specified [RCV004355952] Chr1:47994458 [GRCh38]
Chr1:48460130 [GRCh37]
Chr1:1p33		 likely benign
NM_001194986.2(TRABD2B):c.315C>T (p.His105=) single nucleotide variant not provided [RCV003406485] Chr1:47994385 [GRCh38]
Chr1:48460057 [GRCh37]
Chr1:1p33		 likely benign
Single allele inversion Bilateral polymicrogyria [RCV003459046] Chr1:33246132..61045156 [GRCh38]
Chr1:1p35.1-31.3		 likely pathogenic
GRCh37/hg19 1p33-32.2(chr1:47493178-57042671)x3 copy number gain not specified [RCV003986484] Chr1:47493178..57042671 [GRCh37]
Chr1:1p33-32.2		 likely pathogenic
NM_001194986.2(TRABD2B):c.1075C>A (p.His359Asn) single nucleotide variant not specified [RCV004471089] Chr1:47778458 [GRCh38]
Chr1:48244130 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.784G>T (p.Ala262Ser) single nucleotide variant not specified [RCV004471094] Chr1:47801502 [GRCh38]
Chr1:48267174 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.1243C>A (p.Leu415Ile) single nucleotide variant not specified [RCV004471090] Chr1:47775276 [GRCh38]
Chr1:48240948 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.131C>T (p.Thr44Met) single nucleotide variant not specified [RCV004471091] Chr1:47994569 [GRCh38]
Chr1:48460241 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.386A>G (p.Lys129Arg) single nucleotide variant not specified [RCV004471093] Chr1:47994314 [GRCh38]
Chr1:48459986 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.850G>A (p.Glu284Lys) single nucleotide variant not specified [RCV004471095] Chr1:47794724 [GRCh38]
Chr1:48260396 [GRCh37]
Chr1:1p33		 uncertain significance
NM_001194986.2(TRABD2B):c.850G>C (p.Glu284Gln) single nucleotide variant not specified [RCV004471096] Chr1:47794724 [GRCh38]
Chr1:48260396 [GRCh37]
Chr1:1p33		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3043
Count of miRNA genes:1121
Interacting mature miRNAs:1404
Transcripts:ENST00000435576, ENST00000594280, ENST00000606738
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D1S2134  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37148,281,268 - 48,281,554UniSTSGRCh37
Build 36148,053,855 - 48,054,141RGDNCBI36
Celera146,568,073 - 46,568,343RGD
Cytogenetic Map1p33UniSTS
HuRef146,398,171 - 46,398,441UniSTS
Marshfield Genetic Map175.66RGD
Marshfield Genetic Map175.66UniSTS
deCODE Assembly Map171.29UniSTS
Whitehead-RH Map1163.6UniSTS
SHGC-74778  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37148,226,248 - 48,226,487UniSTSGRCh37
Build 36147,998,835 - 47,999,074RGDNCBI36
Celera146,513,050 - 46,513,289RGD
Cytogenetic Map1p33UniSTS
HuRef146,343,143 - 46,343,382UniSTS
GeneMap99-GB4 RH Map1144.88UniSTS
AL033845  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37148,475,109 - 48,475,191UniSTSGRCh37
Build 36148,247,696 - 48,247,778RGDNCBI36
Celera146,761,964 - 46,762,046RGD
Cytogenetic Map1p33UniSTS
HuRef146,591,746 - 46,591,828UniSTS
AL034124  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37148,485,026 - 48,485,207UniSTSGRCh37
Build 36148,257,613 - 48,257,794RGDNCBI36
Celera146,771,881 - 46,772,062RGD
Cytogenetic Map1p33UniSTS
HuRef146,601,663 - 46,601,844UniSTS
SHGC-147566  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37148,335,037 - 48,335,307UniSTSGRCh37
Build 36148,107,624 - 48,107,894RGDNCBI36
Celera146,621,798 - 46,622,068RGD
Cytogenetic Map1p33UniSTS
HuRef146,451,917 - 46,452,187UniSTS
SHGC-147957  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37148,314,979 - 48,315,278UniSTSGRCh37
Build 36148,087,566 - 48,087,865RGDNCBI36
Celera146,601,775 - 46,602,074RGD
Cytogenetic Map1p33UniSTS
HuRef146,431,869 - 46,432,168UniSTS
SHGC-74794  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37148,231,351 - 48,231,518UniSTSGRCh37
Build 36148,003,938 - 48,004,105RGDNCBI36
Celera146,518,153 - 46,518,320RGD
Cytogenetic Map1p33UniSTS
HuRef146,348,246 - 46,348,413UniSTS
GeneMap99-GB4 RH Map1145.91UniSTS
D1S2839  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37148,432,953 - 48,433,181UniSTSGRCh37
Build 36148,205,540 - 48,205,768RGDNCBI36
Celera146,719,708 - 46,719,934RGD
Cytogenetic Map1p33UniSTS
HuRef146,549,559 - 46,549,785UniSTS
AL009451  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37148,490,803 - 48,490,882UniSTSGRCh37
Build 36148,263,390 - 48,263,469RGDNCBI36
Celera146,777,658 - 46,777,737RGD
Cytogenetic Map1p33UniSTS
HuRef146,607,440 - 46,607,519UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 245 1285 24 11 5 11 936 175 234 238 103 30 58 887
Low 2001 785 1593 574 435 414 2896 1376 1181 141 1168 1330 162 1143 1451 1
Below cutoff 126 656 87 29 618 28 493 616 2251 29 128 154 5 3 450

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001194986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006710640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011541443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011541444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011541445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017001260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017001261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017001262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017001263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054336519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_946654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC096541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC099679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL691459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ653416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000435576
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl147,775,238 - 47,994,212 (-)Ensembl
RefSeq Acc Id: ENST00000606738   ⟹   ENSP00000476820
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl147,760,528 - 47,997,385 (-)Ensembl
RefSeq Acc Id: NM_001194986   ⟹   NP_001181915
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,760,528 - 47,997,385 (-)NCBI
GRCh37148,226,200 - 48,463,009 (-)NCBI
HuRef146,343,095 - 46,579,167 (-)NCBI
CHM1_1148,343,333 - 48,579,625 (-)NCBI
T2T-CHM13v2.0147,639,427 - 47,876,248 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006710640   ⟹   XP_006710703
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,760,528 - 47,997,385 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011541443   ⟹   XP_011539745
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,773,704 - 47,997,385 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011541444   ⟹   XP_011539746
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,776,923 - 47,997,385 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011541445   ⟹   XP_011539747
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,775,170 - 47,997,385 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017001260   ⟹   XP_016856749
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,760,528 - 47,997,385 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017001261   ⟹   XP_016856750
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,760,528 - 47,997,385 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017001262   ⟹   XP_016856751
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,760,528 - 47,997,385 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017001263   ⟹   XP_016856752
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,760,528 - 47,818,775 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024446933   ⟹   XP_024302701
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,760,528 - 47,997,385 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024446935   ⟹   XP_024302703
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,760,528 - 47,997,385 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047420060   ⟹   XP_047276016
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,760,528 - 47,821,646 (-)NCBI
RefSeq Acc Id: XM_054336509   ⟹   XP_054192484
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,639,427 - 47,876,248 (-)NCBI
RefSeq Acc Id: XM_054336510   ⟹   XP_054192485
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,639,427 - 47,876,248 (-)NCBI
RefSeq Acc Id: XM_054336511   ⟹   XP_054192486
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,645,055 - 47,876,248 (-)NCBI
RefSeq Acc Id: XM_054336512   ⟹   XP_054192487
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,639,427 - 47,876,248 (-)NCBI
RefSeq Acc Id: XM_054336513   ⟹   XP_054192488
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,639,427 - 47,876,248 (-)NCBI
RefSeq Acc Id: XM_054336514   ⟹   XP_054192489
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,654,347 - 47,876,248 (-)NCBI
RefSeq Acc Id: XM_054336515   ⟹   XP_054192490
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,639,427 - 47,876,248 (-)NCBI
RefSeq Acc Id: XM_054336516   ⟹   XP_054192491
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,639,427 - 47,876,248 (-)NCBI
RefSeq Acc Id: XM_054336517   ⟹   XP_054192492
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,639,427 - 47,697,661 (-)NCBI
RefSeq Acc Id: XM_054336518   ⟹   XP_054192493
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,654,069 - 47,876,248 (-)NCBI
RefSeq Acc Id: XM_054336519   ⟹   XP_054192494
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0147,639,427 - 47,700,528 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001181915 (Get FASTA)   NCBI Sequence Viewer  
  XP_006710703 (Get FASTA)   NCBI Sequence Viewer  
  XP_011539745 (Get FASTA)   NCBI Sequence Viewer  
  XP_011539746 (Get FASTA)   NCBI Sequence Viewer  
  XP_011539747 (Get FASTA)   NCBI Sequence Viewer  
  XP_016856749 (Get FASTA)   NCBI Sequence Viewer  
  XP_016856750 (Get FASTA)   NCBI Sequence Viewer  
  XP_016856751 (Get FASTA)   NCBI Sequence Viewer  
  XP_016856752 (Get FASTA)   NCBI Sequence Viewer  
  XP_024302701 (Get FASTA)   NCBI Sequence Viewer  
  XP_024302703 (Get FASTA)   NCBI Sequence Viewer  
  XP_047276016 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192484 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192485 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192486 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192487 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192488 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192489 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192490 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192491 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192492 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192493 (Get FASTA)   NCBI Sequence Viewer  
  XP_054192494 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A6NFA1 (Get FASTA)   NCBI Sequence Viewer  
  AFN02882 (Get FASTA)   NCBI Sequence Viewer  
  BAC03448 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000476820
  ENSP00000476820.1
Reference Protein Sequences
RefSeq Acc Id: NP_001181915   ⟸   NM_001194986
- Peptide Label: precursor
- UniProtKB: I6U4Y0 (UniProtKB/Swiss-Prot),   A6NFA1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006710703   ⟸   XM_006710640
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011539745   ⟸   XM_011541443
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011539747   ⟸   XM_011541445
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_011539746   ⟸   XM_011541444
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_016856751   ⟸   XM_017001262
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_016856752   ⟸   XM_017001263
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_016856750   ⟸   XM_017001261
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_016856749   ⟸   XM_017001260
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_024302701   ⟸   XM_024446933
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_024302703   ⟸   XM_024446935
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSP00000476820   ⟸   ENST00000606738
RefSeq Acc Id: XP_047276016   ⟸   XM_047420060
- Peptide Label: isoform X11
RefSeq Acc Id: XP_054192487   ⟸   XM_054336512
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054192485   ⟸   XM_054336510
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054192491   ⟸   XM_054336516
- Peptide Label: isoform X8
RefSeq Acc Id: XP_054192490   ⟸   XM_054336515
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054192488   ⟸   XM_054336513
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054192484   ⟸   XM_054336509
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054192494   ⟸   XM_054336519
- Peptide Label: isoform X11
RefSeq Acc Id: XP_054192492   ⟸   XM_054336517
- Peptide Label: isoform X9
RefSeq Acc Id: XP_054192486   ⟸   XM_054336511
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054192493   ⟸   XM_054336518
- Peptide Label: isoform X10
RefSeq Acc Id: XP_054192489   ⟸   XM_054336514
- Peptide Label: isoform X6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A6NFA1-F1-model_v2 AlphaFold A6NFA1 1-517 view protein structure

Promoters
RGD ID:6855476
Promoter ID:EPDNEW_H903
Type:initiation region
Name:TRABD2B_1
Description:TraB domain containing 2B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,996,879 - 47,996,939EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:44200 AgrOrtholog
COSMIC TRABD2B COSMIC
Ensembl Genes ENSG00000269113 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000606738 ENTREZGENE
  ENST00000606738.3 UniProtKB/Swiss-Prot
GTEx ENSG00000269113 GTEx
HGNC ID HGNC:44200 ENTREZGENE
Human Proteome Map TRABD2B Human Proteome Map
InterPro TIKI1/2-like UniProtKB/Swiss-Prot
  TraB_fam UniProtKB/Swiss-Prot
KEGG Report hsa:388630 UniProtKB/Swiss-Prot
NCBI Gene TRABD2B ENTREZGENE
OMIM 614913 OMIM
PANTHER METALLOPROTEASE TIKI2 UniProtKB/Swiss-Prot
  PTHR31120 UniProtKB/Swiss-Prot
Pfam TraB UniProtKB/Swiss-Prot
PharmGKB PA166049114 PharmGKB
UniProt A6NFA1 ENTREZGENE
  I6U4Y0 ENTREZGENE
  TIKI2_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary I6U4Y0 UniProtKB/Swiss-Prot