MIR378I (microRNA 378i) - Rat Genome Database

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Gene: MIR378I (microRNA 378i) Homo sapiens
Analyze
Symbol: MIR378I
Name: microRNA 378i
RGD ID: 5133956
HGNC Page HGNC:41620
Description: Located in extracellular vesicle.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,923,222 - 41,923,297 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,923,222 - 41,923,297 (-)EnsemblGRCh38hg38GRCh38
GRCh372242,319,226 - 42,319,301 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map22q13.2NCBI
HuRef2225,284,822 - 25,284,897 (-)NCBIHuRef
CHM1_12242,279,425 - 42,279,500 (-)NCBICHM1_1
T2T-CHM13v2.02242,402,085 - 42,402,160 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:16381832   PMID:20733160   PMID:28798470  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 22q11.1-13.33(chr22:16916608-50739836)x3 copy number gain See cases [RCV000133646] Chr22:16916608..50739836 [GRCh38]
Chr22:17397498..51178264 [GRCh37]
Chr22:15777498..49525130 [NCBI36]
Chr22:22q11.1-13.33		 pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916743-50739785)x3 copy number gain See cases [RCV000134730] Chr22:16916743..50739785 [GRCh38]
Chr22:17397633..51178213 [GRCh37]
Chr22:15777633..49525079 [NCBI36]
Chr22:22q11.1-13.33		 pathogenic
GRCh38/hg38 22q13.1-13.33(chr22:40202014-50735806)x3 copy number gain See cases [RCV000134513] Chr22:40202014..50735806 [GRCh38]
Chr22:40598018..51174234 [GRCh37]
Chr22:38927964..49521100 [NCBI36]
Chr22:22q13.1-13.33		 pathogenic
GRCh38/hg38 22q13.2(chr22:41645339-42565798)x1 copy number loss See cases [RCV000136528] Chr22:41645339..42565798 [GRCh38]
Chr22:42041343..42961804 [GRCh37]
Chr22:40371289..41291748 [NCBI36]
Chr22:22q13.2		 uncertain significance
GRCh38/hg38 22q13.2-13.33(chr22:41871143-50739836)x1 copy number loss See cases [RCV000136921] Chr22:41871143..50739836 [GRCh38]
Chr22:42267147..51178264 [GRCh37]
Chr22:40597093..49525130 [NCBI36]
Chr22:22q13.2-13.33		 pathogenic
GRCh38/hg38 22q13.2(chr22:41277822-42414957)x3 copy number gain See cases [RCV000136785] Chr22:41277822..42414957 [GRCh38]
Chr22:41673826..42810963 [GRCh37]
Chr22:40003772..41140907 [NCBI36]
Chr22:22q13.2		 pathogenic
GRCh38/hg38 22q13.2(chr22:41764466-41998153)x3 copy number gain See cases [RCV000142720] Chr22:41764466..41998153 [GRCh38]
Chr22:42160470..42394157 [GRCh37]
Chr22:40490416..40724103 [NCBI36]
Chr22:22q13.2		 uncertain significance
GRCh38/hg38 22q12.3-13.33(chr22:33768441-50739977)x3 copy number gain See cases [RCV000051682] Chr22:33768441..50739977 [GRCh38]
Chr22:34164428..51178405 [GRCh37]
Chr22:32494428..49525271 [NCBI36]
Chr22:22q12.3-13.33		 pathogenic
GRCh38/hg38 22q12.3-13.33(chr22:37061769-50738932)x3 copy number gain See cases [RCV000051684] Chr22:37061769..50738932 [GRCh38]
Chr22:37457809..51177360 [GRCh37]
Chr22:35787755..49524226 [NCBI36]
Chr22:22q12.3-13.33		 pathogenic
NC_000022.11:g.(?_41301335)_(42070317_?)del deletion Immunodeficiency, common variable, 4 [RCV000648330] Chr22:41301335..42070317 [GRCh38]
Chr22:41697339..42466321 [GRCh37]
Chr22:22q13.2		 uncertain significance
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:13150
Count of gene targets:6313
Count of transcripts:11320
Interacting mature miRNAs:hsa-miR-378i
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENST00000582688
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2241,923,222 - 41,923,297 (-)Ensembl
RefSeq Acc Id: NR_039760
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,923,222 - 41,923,297 (-)NCBI
GRCh372242,319,226 - 42,319,301 (-)ENTREZGENE
HuRef2225,284,822 - 25,284,897 (-)ENTREZGENE
CHM1_12242,279,425 - 42,279,500 (-)NCBI
T2T-CHM13v2.02242,402,085 - 42,402,160 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC MIR378I COSMIC
Ensembl Genes ENSG00000283829 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000582688 ENTREZGENE
GTEx ENSG00000283829 GTEx
HGNC ID HGNC:41620 ENTREZGENE
Human Proteome Map MIR378I Human Proteome Map
miRBase MI0016902 ENTREZGENE
NCBI Gene 100616259 ENTREZGENE
RNAcentral URS0000480E22 RNACentral
  URS000075DA4C RNACentral