MIR302E (microRNA 302e) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: MIR302E (microRNA 302e) Homo sapiens
Analyze
Symbol: MIR302E
Name: microRNA 302e
RGD ID: 3516309
HGNC Page HGNC:35348
Description: Enables mRNA base-pairing translational repressor activity. Involved in miRNA-mediated post-transcriptional gene silencing and negative regulation of acute inflammatory response to antigenic stimulus.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: MIRN302E
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,234,766 - 7,234,837 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,234,766 - 7,234,837 (+)EnsemblGRCh38hg38GRCh38
GRCh37117,255,997 - 7,256,068 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera117,375,094 - 7,375,165 (+)NCBICelera
Cytogenetic Map11p15.4ENTREZGENE
HuRef116,914,507 - 6,914,578 (+)NCBIHuRef
CHM1_1117,254,924 - 7,254,995 (+)NCBICHM1_1
T2T-CHM13v2.0117,293,470 - 7,293,541 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:18285502   PMID:29748238   PMID:30221705   PMID:31332696   PMID:31639291  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11p15.5-15.1(chr11:446754-18904742)x3 copy number gain See cases [RCV000133997] Chr11:446754..18904742 [GRCh38]
Chr11:446754..18926289 [GRCh37]
Chr11:436754..18882865 [NCBI36]
Chr11:11p15.5-15.1		 pathogenic
GRCh38/hg38 11p15.4(chr11:7187414-7707594)x3 copy number gain See cases [RCV000139155] Chr11:7187414..7707594 [GRCh38]
Chr11:7208645..7729141 [GRCh37]
Chr11:7165221..7685717 [NCBI36]
Chr11:11p15.4		 uncertain significance
GRCh38/hg38 11p15.5-15.4(chr11:61793-10727969)x3 copy number gain See cases [RCV000139987] Chr11:61793..10727969 [GRCh38]
Chr11:61793..10749516 [GRCh37]
Chr11:51793..10706092 [NCBI36]
Chr11:11p15.5-15.4		 pathogenic
GRCh38/hg38 11p15.5-13(chr11:202758-31726224)x3 copy number gain See cases [RCV000053613] Chr11:202758..31726224 [GRCh38]
Chr11:202758..31747772 [GRCh37]
Chr11:192758..31704348 [NCBI36]
Chr11:11p15.5-13		 pathogenic
GRCh38/hg38 11p15.4(chr11:3745061-7846057)x3 copy number gain See cases [RCV000053616] Chr11:3745061..7846057 [GRCh38]
Chr11:3766291..7867604 [GRCh37]
Chr11:3722867..7824180 [NCBI36]
Chr11:11p15.4		 pathogenic
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:15579
Count of gene targets:7388
Count of transcripts:12763
Interacting mature miRNAs:hsa-miR-302e
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium
Low 1 1 2 2 3 1 2 1 5 3 1 1 2
Below cutoff 2 2 1 1 3 1 2 1 2 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000408776
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl117,234,766 - 7,234,837 (+)Ensembl
RefSeq Acc Id: NR_031683
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38117,234,766 - 7,234,837 (+)NCBI
GRCh37117,255,997 - 7,256,068 (+)RGD
Celera117,375,094 - 7,375,165 (+)RGD
HuRef116,914,507 - 6,914,578 (+)RGD
CHM1_1117,254,924 - 7,254,995 (+)NCBI
T2T-CHM13v2.0117,293,470 - 7,293,541 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC MIR302E COSMIC
Ensembl Genes ENSG00000221703 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000408776 ENTREZGENE
GTEx ENSG00000221703 GTEx
HGNC ID HGNC:35348 ENTREZGENE
Human Proteome Map MIR302E Human Proteome Map
miRBase MI0006417 ENTREZGENE
NCBI Gene 100313774 ENTREZGENE
PharmGKB PA164722639 PharmGKB
RNAcentral URS000075B201 RNACentral
  URS000075E566 RNACentral