SHISA7 (shisa family member 7) - Rat Genome Database

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Gene: SHISA7 (shisa family member 7) Homo sapiens
Analyze
Symbol: SHISA7
Name: shisa family member 7
RGD ID: 3160565
HGNC Page HGNC:35409
Description: Predicted to enable GABA receptor binding activity and ionotropic glutamate receptor binding activity. Predicted to be involved in several processes, including gamma-aminobutyric acid receptor clustering; gamma-aminobutyric acid signaling pathway; and regulation of synaptic plasticity. Predicted to be located in asymmetric, glutamatergic, excitatory synapse. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in glutamatergic synapse; postsynaptic density; and synaptic membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CKAMP59; cystine-knot AMPAR modulating protein of 59 kDa; DKFZp547H0214; FLJ34341; FLJ37640; FLJ45290; GABA(A) receptor auxiliary subunit Shisa7; MGC120935; MGC138402; protein shisa-6-like; protein shisa-7; shisa homolog 7; UPF0626 protein A
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,428,740 - 55,443,300 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,428,740 - 55,443,300 (-)EnsemblGRCh38hg38GRCh38
GRCh371955,940,107 - 55,954,667 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,636,335 - 60,654,784 (-)NCBINCBI36Build 36hg18NCBI36
Celera1952,980,996 - 53,005,709 (-)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,261,714 - 52,265,905 (-)NCBIHuRef
CHM1_11955,933,703 - 55,947,827 (-)NCBICHM1_1
T2T-CHM13v2.01958,524,194 - 58,538,751 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11181995   PMID:12477932   PMID:14702039   PMID:15057824   PMID:21873635   PMID:32655015   PMID:36724073  


Genomics

Comparative Map Data
SHISA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,428,740 - 55,443,300 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,428,740 - 55,443,300 (-)EnsemblGRCh38hg38GRCh38
GRCh371955,940,107 - 55,954,667 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,636,335 - 60,654,784 (-)NCBINCBI36Build 36hg18NCBI36
Celera1952,980,996 - 53,005,709 (-)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,261,714 - 52,265,905 (-)NCBIHuRef
CHM1_11955,933,703 - 55,947,827 (-)NCBICHM1_1
T2T-CHM13v2.01958,524,194 - 58,538,751 (-)NCBIT2T-CHM13v2.0
Shisa7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3974,828,551 - 4,847,788 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl74,828,551 - 4,847,695 (-)EnsemblGRCm39 Ensembl
GRCm3874,825,551 - 4,844,866 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl74,825,552 - 4,844,696 (-)EnsemblGRCm38mm10GRCm38
MGSCv3774,777,154 - 4,796,298 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3674,431,561 - 4,442,291 (-)NCBIMGSCv36mm8
Celera74,563,009 - 4,582,132 (-)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.79NCBI
Shisa7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,022,680 - 78,041,748 (+)NCBIGRCr8
mRatBN7.2168,993,900 - 69,012,943 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,994,025 - 69,012,943 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx174,339,062 - 74,357,989 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0182,903,373 - 82,922,296 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,052,129 - 76,071,041 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,545,413 - 72,564,513 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,545,596 - 72,564,513 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0175,971,937 - 75,990,945 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,710,526 - 67,729,443 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera168,111,510 - 68,130,334 (-)NCBICelera
Cytogenetic Map1q12NCBI
Shisa7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955567840,193 - 845,093 (+)NCBIChiLan1.0ChiLan1.0
SHISA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,571,316 - 61,592,508 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,300,330 - 63,321,069 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,475,852 - 52,496,819 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11961,165,673 - 61,175,020 (-)NCBIpanpan1.1PanPan1.1panPan2
SHISA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,260,917 - 102,270,388 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,261,484 - 102,268,179 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1102,310,808 - 102,328,742 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01102,907,280 - 102,925,221 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1102,905,126 - 102,925,247 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,544,484 - 102,562,438 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,256,598 - 102,274,537 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01103,019,825 - 103,037,770 (+)NCBIUU_Cfam_GSD_1.0
Shisa7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093491,878,026 - 1,895,150 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936886664,052 - 682,618 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936886664,075 - 675,008 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHISA7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,582,708 - 59,601,885 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,582,706 - 59,601,979 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SHISA7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1648,028,539 - 48,049,478 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045677,739 - 697,961 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Shisa7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,900,580 - 1,909,125 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248321,898,049 - 1,909,155 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SHISA7
13 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3 copy number gain See cases [RCV000050883] Chr19:50191219..58535818 [GRCh38]
Chr19:50694476..59047185 [GRCh37]
Chr19:55386288..63738997 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3 copy number gain See cases [RCV000052925] Chr19:49907832..58557889 [GRCh38]
Chr19:50411089..59069256 [GRCh37]
Chr19:55102901..63761068 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:51141518-58539965)x3 copy number gain See cases [RCV000052926] Chr19:51141518..58539965 [GRCh38]
Chr19:51644775..59051332 [GRCh37]
Chr19:56336587..63743144 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52612432-58581203)x3 copy number gain See cases [RCV000134174] Chr19:52612432..58581203 [GRCh38]
Chr19:53115685..59092570 [GRCh37]
Chr19:57807497..63784382 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52955056-58581203)x3 copy number gain See cases [RCV000134139] Chr19:52955056..58581203 [GRCh38]
Chr19:53458309..59092570 [GRCh37]
Chr19:58150121..63784382 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3 copy number gain See cases [RCV000135843] Chr19:50152520..58581203 [GRCh38]
Chr19:50655777..59092570 [GRCh37]
Chr19:55347589..63784382 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.42-13.43(chr19:55048514-56972458)x3 copy number gain See cases [RCV000138139] Chr19:55048514..56972458 [GRCh38]
Chr19:55595687..57483826 [GRCh37]
Chr19:60251694..62175638 [NCBI36]
Chr19:19q13.42-13.43		 likely pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52143873-58445521)x3 copy number gain See cases [RCV000142008] Chr19:52143873..58445521 [GRCh38]
Chr19:52647126..58956888 [GRCh37]
Chr19:57338938..63648700 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.42-13.43(chr19:55037146-56982033)x3 copy number gain See cases [RCV000142245] Chr19:55037146..56982033 [GRCh38]
Chr19:55548514..57493401 [GRCh37]
Chr19:60240326..62185213 [NCBI36]
Chr19:19q13.42-13.43		 uncertain significance
GRCh38/hg38 19q13.42(chr19:55066790-55789870)x3 copy number gain See cases [RCV000142067] Chr19:55066790..55789870 [GRCh38]
Chr19:55578158..56301236 [GRCh37]
Chr19:60269970..60993048 [NCBI36]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3 copy number gain See cases [RCV000445925] Chr19:50489390..59095359 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:54344821-58956888)x3 copy number gain See cases [RCV000448186] Chr19:54344821..58956888 [GRCh37]
Chr19:19q13.42-13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
GRCh37/hg19 19q13.42-13.43(chr19:55549385-57489784)x3 copy number gain See cases [RCV000510290] Chr19:55549385..57489784 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
GRCh37/hg19 19q13.42-13.43(chr19:55844155-57408007)x3 copy number gain See cases [RCV000511123] Chr19:55844155..57408007 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
GRCh37/hg19 19q13.42-13.43(chr19:55779884-56896574)x1 copy number loss not provided [RCV000684089] Chr19:55779884..56896574 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
GRCh37/hg19 19q13.42-13.43(chr19:54196216-58759679)x3 copy number gain not provided [RCV000684095] Chr19:54196216..58759679 [GRCh37]
Chr19:19q13.42-13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3 copy number gain not provided [RCV000740208] Chr19:50740074..59097160 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
NM_001145176.2(SHISA7):c.1076G>T (p.Gly359Val) single nucleotide variant not specified [RCV004292522] Chr19:55433697 [GRCh38]
Chr19:55945064 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19q13.42(chr19:55909965-55975611)x1 copy number loss not provided [RCV002472807] Chr19:55909965..55975611 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19q13.42-13.43(chr19:54334195-56434037)x3 copy number gain not provided [RCV001259948] Chr19:54334195..56434037 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3 copy number gain not provided [RCV001259944] Chr19:48463931..57095254 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:55247893-56503347)x1 copy number loss not provided [RCV001834407] Chr19:55247893..56503347 [GRCh37]
Chr19:19q13.42-13.43		 likely pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:55434660-56463734)x1 copy number loss not provided [RCV002279751] Chr19:55434660..56463734 [GRCh37]
Chr19:19q13.42-13.43		 uncertain significance
NM_001145176.2(SHISA7):c.434G>C (p.Gly145Ala) single nucleotide variant not specified [RCV004112534] Chr19:55442430 [GRCh38]
Chr19:55953797 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1013G>A (p.Arg338Gln) single nucleotide variant not specified [RCV004099632] Chr19:55433760 [GRCh38]
Chr19:55945127 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.239A>C (p.Glu80Ala) single nucleotide variant not specified [RCV004113612] Chr19:55442625 [GRCh38]
Chr19:55953992 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1441G>T (p.Ala481Ser) single nucleotide variant not specified [RCV004204394] Chr19:55433332 [GRCh38]
Chr19:55944699 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1214C>T (p.Ala405Val) single nucleotide variant not specified [RCV004165179] Chr19:55433559 [GRCh38]
Chr19:55944926 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1501C>G (p.Leu501Val) single nucleotide variant not specified [RCV004075530] Chr19:55433272 [GRCh38]
Chr19:55944639 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.62C>A (p.Pro21Gln) single nucleotide variant not specified [RCV004082127] Chr19:55442802 [GRCh38]
Chr19:55954169 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1193A>G (p.Tyr398Cys) single nucleotide variant not specified [RCV004165164] Chr19:55433580 [GRCh38]
Chr19:55944947 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.814A>C (p.Thr272Pro) single nucleotide variant not specified [RCV004268105] Chr19:55440623 [GRCh38]
Chr19:55951990 [GRCh37]
Chr19:19q13.42		 likely benign
NM_001145176.2(SHISA7):c.1031G>A (p.Arg344His) single nucleotide variant not specified [RCV004259293] Chr19:55433742 [GRCh38]
Chr19:55945109 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1021G>C (p.Glu341Gln) single nucleotide variant not specified [RCV004248677] Chr19:55433752 [GRCh38]
Chr19:55945119 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.22G>C (p.Val8Leu) single nucleotide variant not specified [RCV004339256] Chr19:55442842 [GRCh38]
Chr19:55954209 [GRCh37]
Chr19:19q13.42		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3 copy number gain not provided [RCV003485200] Chr19:49625130..57647352 [GRCh37]
Chr19:19q13.33-13.43		 likely pathogenic
NM_001145176.2(SHISA7):c.1319A>C (p.Asp440Ala) single nucleotide variant not specified [RCV004451077] Chr19:55433454 [GRCh38]
Chr19:55944821 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1463C>G (p.Pro488Arg) single nucleotide variant not specified [RCV004451080] Chr19:55433310 [GRCh38]
Chr19:55944677 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1399G>A (p.Gly467Arg) single nucleotide variant not specified [RCV004451078] Chr19:55433374 [GRCh38]
Chr19:55944741 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1117G>A (p.Gly373Ser) single nucleotide variant not specified [RCV004451074] Chr19:55433656 [GRCh38]
Chr19:55945023 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1255G>A (p.Glu419Lys) single nucleotide variant not specified [RCV004451076] Chr19:55433518 [GRCh38]
Chr19:55944885 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.151G>A (p.Gly51Arg) single nucleotide variant not specified [RCV004451081] Chr19:55442713 [GRCh38]
Chr19:55954080 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.334T>C (p.Tyr112His) single nucleotide variant not specified [RCV004451083] Chr19:55442530 [GRCh38]
Chr19:55953897 [GRCh37]
Chr19:19q13.42		 uncertain significance
NM_001145176.2(SHISA7):c.1450G>A (p.Gly484Ser) single nucleotide variant not specified [RCV004451079] Chr19:55433323 [GRCh38]
Chr19:55944690 [GRCh37]
Chr19:19q13.42		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3580
Count of miRNA genes:998
Interacting mature miRNAs:1221
Transcripts:ENST00000376325, ENST00000416792
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH98724  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371955,964,475 - 55,964,595UniSTSGRCh37
Build 361960,656,287 - 60,656,407RGDNCBI36
Celera1953,004,567 - 53,004,688RGD
Cytogenetic Map19q13.42UniSTS
HuRef1952,278,597 - 52,278,717UniSTS
GeneMap99-GB4 RH Map19289.56UniSTS
NIB1495  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371955,940,129 - 55,940,235UniSTSGRCh37
Build 361960,631,941 - 60,632,047RGDNCBI36
Celera1952,981,020 - 52,981,126RGD
Cytogenetic Map19q13.42UniSTS
HuRef1952,261,738 - 52,261,844UniSTS
GeneMap99-GB4 RH Map19287.85UniSTS
Whitehead-RH Map19367.3UniSTS
NCBI RH Map19599.8UniSTS
RH11812  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371955,940,172 - 55,940,362UniSTSGRCh37
Build 361960,631,984 - 60,632,174RGDNCBI36
Celera1952,981,063 - 52,981,253RGD
Cytogenetic Map19q13.42UniSTS
HuRef1952,261,781 - 52,261,971UniSTS
GeneMap99-GB4 RH Map19284.08UniSTS
UniSTS:484430  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371955,943,525 - 55,944,300UniSTSGRCh37
Celera1952,984,416 - 52,985,191UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 1 125 2 1 2 263 12 2385 2 17 263
Low 161 113 205 10 136 10 570 20 1274 12 422 46 1 32 380
Below cutoff 2097 2743 1094 379 1393 221 3330 2053 39 161 855 1315 164 1 1090 2052 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000376325   ⟹   ENSP00000365503
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,428,740 - 55,443,300 (-)Ensembl
RefSeq Acc Id: ENST00000416792   ⟹   ENSP00000401307
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1955,431,976 - 55,443,277 (-)Ensembl
RefSeq Acc Id: NM_001145176   ⟹   NP_001138648
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381955,428,740 - 55,443,300 (-)NCBI
GRCh371955,940,105 - 55,954,230 (-)RGD
Celera1952,980,996 - 53,005,709 (-)RGD
HuRef1952,261,714 - 52,265,905 (-)ENTREZGENE
CHM1_11955,933,703 - 55,947,827 (-)NCBI
T2T-CHM13v2.01958,524,194 - 58,538,751 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001138648   ⟸   NM_001145176
- Peptide Label: precursor
- UniProtKB: A6NL88 (UniProtKB/Swiss-Prot),   H7C1N4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000365503   ⟸   ENST00000376325
RefSeq Acc Id: ENSP00000401307   ⟸   ENST00000416792

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A6NL88-F1-model_v2 AlphaFold A6NL88 1-538 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:35409 AgrOrtholog
COSMIC SHISA7 COSMIC
Ensembl Genes ENSG00000187902 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000376325 ENTREZGENE
  ENST00000376325.10 UniProtKB/Swiss-Prot
  ENST00000416792.2 UniProtKB/TrEMBL
GTEx ENSG00000187902 GTEx
HGNC ID HGNC:35409 ENTREZGENE
Human Proteome Map SHISA7 Human Proteome Map
InterPro Shisa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:729956 UniProtKB/Swiss-Prot
NCBI Gene 729956 ENTREZGENE
OMIM 617328 OMIM
PANTHER PROTEIN SHISA-7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR31774 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Shisa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA165394299 PharmGKB
UniProt A6NL88 ENTREZGENE
  H7C1N4 ENTREZGENE, UniProtKB/TrEMBL
  SHSA7_HUMAN UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-06 SHISA7  shisa family member 7    shisa homolog 7 (Xenopus laevis)  Symbol and/or name change 5135510 APPROVED