Ighl7 (immunoglobulin heavy chain like 7) - Rat Genome Database

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Gene: Ighl7 (immunoglobulin heavy chain like 7) Rattus norvegicus
Analyze
Symbol: Ighl7 (Ensembl: LOC100361324)
Name: immunoglobulin heavy chain like 7 (Ensembl:hypothetical LOC100361324)
RGD ID: 2320341
Description: Predicted to be part of immunoglobulin complex. Orthologous to several human genes including IGHV4-28 (immunoglobulin heavy variable 4-28); IGHV4-31 (immunoglobulin heavy variable 4-31); and IGHV4-34 (immunoglobulin heavy variable 4-34).
Type: gene (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: AABR07065790.1; hypothetical LOC100361324; LOC100361324
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86140,727,663 - 140,728,174 (-)NCBIGRCr8
mRatBN7.26134,584,503 - 134,585,017 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6134,584,503 - 134,585,002 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl6134,584,503 - 134,585,002 (-)NCBImRatBN7.2 Ensembl
Rnor_6.06141,246,271 - 141,257,218 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6141,383,872 - 141,384,305 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.06150,224,992 - 150,225,422 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46140,890,818 - 140,891,817 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6132,278,529 - 132,279,026 (-)NCBICelera
Cytogenetic Map6q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Comparative Map Data
Ighl7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86140,727,663 - 140,728,174 (-)NCBIGRCr8
mRatBN7.26134,584,503 - 134,585,017 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6134,584,503 - 134,585,002 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl6134,584,503 - 134,585,002 (-)NCBImRatBN7.2 Ensembl
Rnor_6.06141,246,271 - 141,257,218 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6141,383,872 - 141,384,305 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.06150,224,992 - 150,225,422 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46140,890,818 - 140,891,817 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6132,278,529 - 132,279,026 (-)NCBICelera
Cytogenetic Map6q33NCBI
IGHV4-31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814106,349,283 - 106,349,720 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14106,349,283 - 106,349,792 (-)EnsemblGRCh38hg38GRCh38
GRCh3714106,805,207 - 106,805,644 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3614105,876,252 - 105,876,689 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map14q32.33NCBI
HuRef1486,942,185 - 86,942,622 (-)NCBIHuRef
CHM1_114106,686,239 - 106,686,676 (-)NCBICHM1_1

Variants

.
Variants in Ighl7
25 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat


Expression


Sequence

Nucleotide Sequences
GenBank Nucleotide JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000045320   ⟹   ENSRNOP00000046364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6134,584,503 - 134,585,002 (-)Ensembl
Protein Sequences
Ensembl Protein ENSRNOP00000046364.5
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000046364   ⟸   ENSRNOT00000045320
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZK57-F1-model_v2 AlphaFold D3ZK57 1-116 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2320341 AgrOrtholog
BioCyc Gene G2FUF-35664 BioCyc
Ensembl Genes ENSRNOG00000029121 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045320.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
NCBI Gene 100361324 ENTREZGENE
PANTHER IMMUNOGLOBULIN HEAVY CHAIN UniProtKB/TrEMBL
  IMMUNOGLOBULIN HEAVY VARIABLE 4-4 UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PhenoGen Ighl7 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029121 RatGTEx
SMART IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt D3ZK57_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Ighl7  immunoglobulin heavy chain like 7  LOC100361324  hypothetical LOC100361324  Symbol and Name Changed 1299863 APPROVED
2022-06-02 LOC100361324  hypothetical LOC100361324  AABR07065790.1    Data merged from RGD:15003726 737654 PROVISIONAL
2019-11-08 AABR07065790.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2010-05-05 LOC100361324  hypothetical LOC100361324      Symbol and Name status set to provisional 70820 PROVISIONAL