WASH2P (WASP family homolog 2, pseudogene) - Rat Genome Database

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Gene: WASH2P (WASP family homolog 2, pseudogene) Homo sapiens
Analyze
No known orthologs.
Symbol: WASH2P
Name: WASP family homolog 2, pseudogene
RGD ID: 2299988
HGNC Page HGNC:33145
Description: Predicted to enable alpha-tubulin binding activity and gamma-tubulin binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation; endosomal transport; and exocytosis. Predicted to be located in several cellular components, including autophagosome; centriole; and endosome. Predicted to be part of WASH complex. Predicted to be active in early endosome and recycling endosome.
Type: pseudo (Ensembl: transcribed_unprocessed_pseudogene)
RefSeq Status: VALIDATED
Previously known as: DKFZp434K1323; FAM39B; FLJ77647; FLJ98615; MGC104889; MGC111476; MGC117230; MGC52000; MGC90409; WAS protein family homolog 2 pseudogene; WAS protein family homolog 2, pseudogene
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: WASHC1  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382113,583,653 - 113,599,037 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2113,583,593 - 113,599,081 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl2113,588,550 - 113,599,034 (+)EnsemblGRCh38hg38GRCh38
GRCh372114,341,230 - 114,356,614 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362114,057,453 - 114,074,065 (+)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map2q14.1NCBI
CHM1_12114,345,822 - 114,361,209 (+)NCBICHM1_1
T2T-CHM13v2.02114,008,336 - 114,023,723 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10655549   PMID:11701968   PMID:12477932   PMID:15233989   PMID:16344560   PMID:18159949   PMID:20936779   PMID:21244100   PMID:21832049   PMID:21900206   PMID:21988832   PMID:26760575  
PMID:36215168  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1081
Count of miRNA genes:388
Interacting mature miRNAs:417
Transcripts:ENST00000326632, ENST00000453662, ENST00000538033
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH26395  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37914,524 - 14,629UniSTSGRCh37
Build 3694,524 - 4,629RGDNCBI36
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map2q13UniSTS
ECD07852  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372114,352,124 - 114,352,794UniSTSGRCh37
GRCh371667,901 - 68,571UniSTSGRCh37
Build 362114,068,594 - 114,069,264RGDNCBI36
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map2q13UniSTS
D1S3693  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map3p22UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map20q11.21UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map1q22-q23UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map12p13.3UniSTS
Cytogenetic Map15q14UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11.32UniSTS
Cytogenetic Map10p15.3-p15.2UniSTS
Cytogenetic Map13q14.13UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map3p22.3UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map1q32.3-q41UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map1p36.32UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map17q12UniSTS
ECD09355  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map2q13UniSTS
ECD12236  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map2q13UniSTS
ECD03212  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXq28UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic MapYq12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1122 680 911 84 660 57 1906 618 1601 152 1171 1022 36 332 1289 1
Low 1310 2302 812 538 1155 407 2449 1574 2107 266 277 585 134 872 1499 3
Below cutoff 2 124 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_024077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC245097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF328424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL078621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL137714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY217347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY341936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY341937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC073149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC073913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC082240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC106020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX377099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX537637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA685507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000453662
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,588,550 - 113,599,034 (+)Ensembl
RefSeq Acc Id: ENST00000538033
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,594,176 - 113,599,043 (+)Ensembl
RefSeq Acc Id: ENST00000685302
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,637 - 113,599,033 (+)Ensembl
RefSeq Acc Id: ENST00000685435
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,640 - 113,599,079 (+)Ensembl
RefSeq Acc Id: ENST00000685518
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,648 - 113,599,030 (+)Ensembl
RefSeq Acc Id: ENST00000686495
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,593 - 113,599,081 (+)Ensembl
RefSeq Acc Id: ENST00000688542
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,637 - 113,599,079 (+)Ensembl
RefSeq Acc Id: ENST00000691953
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,655 - 113,599,041 (+)Ensembl
RefSeq Acc Id: ENST00000692602
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,604 - 113,599,079 (+)Ensembl
RefSeq Acc Id: ENST00000702058
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,712 - 113,599,033 (+)Ensembl
RefSeq Acc Id: ENST00000702155
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,646 - 113,599,079 (+)Ensembl
RefSeq Acc Id: ENST00000702598
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,653 - 113,599,037 (+)Ensembl
RefSeq Acc Id: ENST00000702783
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,613 - 113,599,037 (+)Ensembl
RefSeq Acc Id: ENST00000702861
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,583,597 - 113,599,041 (+)Ensembl
RefSeq Acc Id: NR_024077
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382113,583,653 - 113,599,037 (+)NCBI
GRCh372114,341,230 - 114,356,614 (+)RGD
HuRef2768 - 5,830 (-)RGD
CHM1_12114,345,822 - 114,361,209 (+)NCBI
T2T-CHM13v2.02114,008,336 - 114,023,723 (+)NCBI
Sequence:
Protein Domains
WH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6VEQ5-F1-model_v2 AlphaFold Q6VEQ5 1-465 view protein structure

Promoters
RGD ID:6797075
Promoter ID:HG_KWN:34630
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid,   NB4
Transcripts:ENST00000285718,   NR_024077,   UC002TKA.1,   UC002TKB.2
Position:
Human AssemblyChrPosition (strand)Source
Build 362114,057,819 - 114,058,319 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:33145 AgrOrtholog
COSMIC WASH2P COSMIC
Ensembl Genes ENSG00000146556 Ensembl
  ENSG00000291134 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000692602 ENTREZGENE
GTEx ENSG00000146556 GTEx
  ENSG00000291134 GTEx
HGNC ID HGNC:33145 ENTREZGENE
Human Proteome Map WASH2P Human Proteome Map
InterPro WASH1 UniProtKB/Swiss-Prot
  WASH1_WAHD UniProtKB/Swiss-Prot
  WH2_dom UniProtKB/Swiss-Prot
NCBI Gene 375260 ENTREZGENE
PANTHER PTHR23331 UniProtKB/Swiss-Prot
  WAS PROTEIN FAMILY HOMOLOG 2-RELATED UniProtKB/Swiss-Prot
Pfam WASH_WAHD UniProtKB/Swiss-Prot
PROSITE WH2 UniProtKB/Swiss-Prot
UniProt WASH2_HUMAN UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 WASH2P  WASP family homolog 2, pseudogene    WAS protein family homolog 2, pseudogene  Symbol and/or name change 5135510 APPROVED
2018-06-12 WASH2P  WAS protein family homolog 2, pseudogene    WAS protein family homolog 2 pseudogene  Symbol and/or name change 5135510 APPROVED