MIR942 (microRNA 942) - Rat Genome Database

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Gene: MIR942 (microRNA 942) Homo sapiens
Analyze
Symbol: MIR942
Name: microRNA 942
RGD ID: 2290224
HGNC Page HGNC:33688
Description: Predicted to be involved in miRNA-mediated post-transcriptional gene silencing. Predicted to be part of RISC complex.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: hsa-mir-942; mir-942; MIRN942
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381117,094,643 - 117,094,728 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1117,094,643 - 117,094,728 (+)EnsemblGRCh38hg38GRCh38
GRCh371117,637,265 - 117,637,350 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361117,438,787 - 117,438,872 (+)NCBINCBI36Build 36hg18NCBI36
Celera1115,865,873 - 115,865,958 (+)NCBICelera
Cytogenetic Map1p13.1NCBI
HuRef1115,495,262 - 115,495,347 (+)NCBIHuRef
CHM1_11117,752,169 - 117,752,254 (+)NCBICHM1_1
T2T-CHM13v2.01117,105,066 - 117,105,151 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
RISC complex  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:17616659   PMID:21037258   PMID:23034410   PMID:24727952   PMID:24970806   PMID:25844602   PMID:27440900   PMID:28287888   PMID:28438567   PMID:29715124   PMID:30097701  
PMID:30887698   PMID:31046434   PMID:31278963   PMID:31545458   PMID:31804461   PMID:31962131   PMID:32026471   PMID:32217695   PMID:32572890   PMID:32772782   PMID:32826876   PMID:32856218  
PMID:33054543   PMID:33128289   PMID:33336744   PMID:33997050   PMID:34518440   PMID:34562344   PMID:34607512   PMID:34906917   PMID:35030971   PMID:35230201   PMID:35974384   PMID:36054164  
PMID:36434360   PMID:36581942   PMID:36730637   PMID:36848349   PMID:37382169   PMID:38262261  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1p13.1-12(chr1:116752007-117309842)x3 copy number gain See cases [RCV000137829] Chr1:116752007..117309842 [GRCh38]
Chr1:117294629..117852464 [GRCh37]
Chr1:117096152..117653987 [NCBI36]
Chr1:1p13.1-12		 uncertain significance
GRCh38/hg38 1p21.1-12(chr1:104325484-119977655)x3 copy number gain See cases [RCV000142953] Chr1:104325484..119977655 [GRCh38]
Chr1:104868106..120471049 [GRCh37]
Chr1:104669629..120321801 [NCBI36]
Chr1:1p21.1-12		 pathogenic
GRCh38/hg38 1p13.1-12(chr1:116679122-119290029)x1 copy number loss See cases [RCV000051079] Chr1:116679122..119290029 [GRCh38]
Chr1:117221744..119832652 [GRCh37]
Chr1:117023267..119634175 [NCBI36]
Chr1:1p13.1-12		 pathogenic
GRCh38/hg38 1p13.3-12(chr1:109756630-118650204)x3 copy number gain See cases [RCV000051827] Chr1:109756630..118650204 [GRCh38]
Chr1:110299252..119192827 [GRCh37]
Chr1:110100775..118994350 [NCBI36]
Chr1:1p13.3-12		 pathogenic
GRCh38/hg38 1p13.1-12(chr1:116059621-120130051)x3 copy number gain See cases [RCV000051831] Chr1:116059621..120130051 [GRCh38]
Chr1:116602242..120672637 [GRCh37]
Chr1:116403765..120474160 [NCBI36]
Chr1:1p13.1-12		 pathogenic
miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
CDKN1Ahsa-miR-942-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotNon-Functional MTI20190813
FASNhsa-miR-942-5pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Targets
Summary Value
Count of predictions:43027
Count of gene targets:13786
Count of transcripts:29411
Interacting mature miRNAs:hsa-miR-942-3p, hsa-miR-942-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 5 1
Low 93 12 56 36 315 40 105 42 76 65 109 144 5 9 15 1
Below cutoff 19 10 15 7 11 3 31 19 23 10 21 19 4 9 15 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000401111
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1117,094,643 - 117,094,728 (+)Ensembl
RefSeq Acc Id: NR_030640
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381117,094,643 - 117,094,728 (+)NCBI
GRCh371117,637,265 - 117,637,350 (+)RGD
Celera1115,865,873 - 115,865,958 (+)RGD
HuRef1115,495,262 - 115,495,347 (+)RGD
CHM1_11117,752,169 - 117,752,254 (+)NCBI
T2T-CHM13v2.01117,105,066 - 117,105,151 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC MIR942 COSMIC
Ensembl Genes ENSG00000215930 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000401111 ENTREZGENE
GTEx ENSG00000215930 GTEx
HGNC ID HGNC:33688 ENTREZGENE
Human Proteome Map MIR942 Human Proteome Map
miRBase MI0005767 ENTREZGENE
NCBI Gene 100126331 ENTREZGENE
PharmGKB PA164723018 PharmGKB
RNAcentral URS00005194EC RNACentral
  URS0000712C24 RNACentral
  URS000075C646 RNACentral