Kcnk18 (potassium two pore domain channel subfamily K member 18) - Rat Genome Database

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Gene: Kcnk18 (potassium two pore domain channel subfamily K member 18) Heterocephalus glaber
Analyze
Symbol: Kcnk18
Name: potassium two pore domain channel subfamily K member 18
RGD ID: 18934448
Description: ENCODES a protein that exhibits calcium-activated potassium channel activity (ortholog); INVOLVED IN cellular response to pH (ortholog); potassium ion export across plasma membrane (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH migraine (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium channel subfamily K member 18; potassium channel, subfamily K, member 18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473729,414,733 - 29,425,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
migraine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnk18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473729,414,733 - 29,425,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KCNK18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810117,197,489 - 117,210,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10117,197,489 - 117,210,299 (+)EnsemblGRCh38hg38GRCh38
GRCh3710118,957,000 - 118,969,810 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610118,946,990 - 118,959,800 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410118,946,989 - 118,959,800NCBI
Celera10112,687,102 - 112,699,920 (+)NCBICelera
Cytogenetic Map10q25.3NCBI
HuRef10112,584,507 - 112,597,305 (+)NCBIHuRef
CHM1_110119,241,229 - 119,254,016 (+)NCBICHM1_1
T2T-CHM13v2.010118,091,991 - 118,104,789 (+)NCBIT2T-CHM13v2.0
Kcnk18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391959,208,080 - 59,225,802 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1959,207,646 - 59,225,806 (+)EnsemblGRCm39 Ensembl
GRCm381959,219,648 - 59,237,370 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1959,219,214 - 59,237,374 (+)EnsemblGRCm38mm10GRCm38
MGSCv371959,294,138 - 59,311,860 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361959,272,898 - 59,290,620 (+)NCBIMGSCv36mm8
Celera1961,420,573 - 61,435,885 (+)NCBICelera
Cytogenetic Map19D3NCBI
cM Map1954.63NCBI
Kcnk18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81268,360,738 - 268,375,012 (+)NCBIGRCr8
mRatBN7.21258,374,671 - 258,388,945 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1258,374,671 - 258,388,945 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1266,580,176 - 266,594,492 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01273,286,195 - 273,300,505 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01265,927,693 - 265,941,666 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01280,383,579 - 280,397,784 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1280,383,579 - 280,397,784 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01287,744,272 - 287,758,268 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41265,749,192 - 265,764,641 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11265,960,270 - 265,975,609 (+)NCBI
Celera1254,028,695 - 254,042,550 (+)NCBICelera
Cytogenetic Map1q55NCBI
Kcnk18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543121,916,587 - 21,927,346 (+)NCBIChiLan1.0ChiLan1.0
KCNK18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28129,063,298 - 129,082,154 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110129,068,636 - 129,086,687 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010113,775,944 - 113,792,520 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110117,206,815 - 117,219,701 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10117,206,815 - 117,219,701 (+)Ensemblpanpan1.1panPan2
KCNK18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12827,694,532 - 27,707,607 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2827,694,532 - 27,706,453 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2827,838,011 - 27,851,088 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02828,224,259 - 28,237,339 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2828,224,259 - 28,236,185 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12827,785,267 - 27,798,331 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02827,798,855 - 27,810,744 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02827,993,454 - 28,006,542 (+)NCBIUU_Cfam_GSD_1.0
Kcnk18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721318,508,340 - 18,519,675 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364867,041,623 - 7,075,224 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNK18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.114127,323,291 - 127,335,320 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214138,724,648 - 138,736,336 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNK18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19109,994,379 - 110,009,295 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9109,995,843 - 110,008,739 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604871,252,146 - 71,266,091 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004838849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01015138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_004838849   ⟹   XP_004838906
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473729,414,733 - 29,425,855 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004838906 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000016243
Reference Protein Sequences
RefSeq Acc Id: XP_004838906   ⟸   XM_004838849
- UniProtKB: G5BVW3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011638 ENTREZGENE
Ensembl Transcript ENSHGLT00000016412 ENTREZGENE
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
InterPro 2pore_dom_K_chnl UniProtKB/TrEMBL
  2pore_dom_K_chnl_TASK UniProtKB/TrEMBL
  K_chnl_dom UniProtKB/TrEMBL
NCBI Gene Kcnk18 ENTREZGENE
PANTHER POTASSIUM CHANNEL SUBFAMILY K MEMBER 18 UniProtKB/TrEMBL
  PTHR11003 UniProtKB/TrEMBL
Pfam Ion_trans_2 UniProtKB/TrEMBL
PRINTS 2POREKCHANEL UniProtKB/TrEMBL
  TASKCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt G5BVW3 ENTREZGENE, UniProtKB/TrEMBL