Ocln (occludin) - Rat Genome Database

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Gene: Ocln (occludin) Heterocephalus glaber
Analyze
Symbol: Ocln
Name: occludin
RGD ID: 18932171
Description: ENCODES a protein that exhibits protein domain specific binding (inferred); INVOLVED IN cell-cell junction organization (ortholog); cellular response to tumor necrosis factor (ortholog); positive regulation of lamellipodium assembly (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); allergic rhinitis (ortholog); amenorrhea (ortholog); FOUND IN apical plasma membrane (ortholog); cell leading edge (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624905333,864 - 388,880 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624905333,853 - 388,990 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ocln
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624905333,864 - 388,880 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624905333,853 - 388,990 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
OCLN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38569,492,547 - 69,558,104 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl569,492,292 - 69,558,104 (+)EnsemblGRCh38hg38GRCh38
GRCh37568,788,374 - 68,853,931 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36568,823,875 - 68,885,889 (+)NCBINCBI36Build 36hg18NCBI36
Build 34568,823,874 - 68,885,887NCBI
Cytogenetic Map5q13.2NCBI
HuRef565,744,381 - 65,800,380 (+)NCBIHuRef
HuRef565,800,577 - 65,803,347 (+)NCBIHuRef
CHM1_1568,787,783 - 68,853,763 (+)NCBICHM1_1
T2T-CHM13v2.0570,316,240 - 70,383,882 (+)NCBIT2T-CHM13v2.0
Ocln
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913100,633,012 - 100,689,226 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13100,633,015 - 100,689,226 (-)EnsemblGRCm39 Ensembl
GRCm3813100,496,504 - 100,552,718 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13100,496,507 - 100,552,718 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713101,267,322 - 101,322,453 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613101,597,624 - 101,652,755 (-)NCBIMGSCv36mm8
Celera13104,112,684 - 104,167,697 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1353.23NCBI
Ocln
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8233,391,303 - 33,442,207 (-)NCBIGRCr8
mRatBN7.2231,657,217 - 31,707,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl231,657,220 - 31,764,150 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx238,791,782 - 38,841,944 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0236,819,361 - 36,869,279 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0231,690,347 - 31,739,905 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0230,527,327 - 30,577,218 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl230,527,715 - 30,577,218 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0249,686,707 - 49,737,380 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4231,317,090 - 31,367,485 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1231,237,461 - 31,287,854 (-)NCBI
Celera227,670,881 - 27,719,967 (-)NCBICelera
Cytogenetic Map2q12NCBI
Ocln
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955575163,646 - 210,379 (+)NCBIChiLan1.0ChiLan1.0
OCLN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2444,366,263 - 44,428,662 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1542,519,888 - 42,582,278 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0544,447,230 - 44,509,637 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1546,022,538 - 46,080,549 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl546,023,437 - 46,069,342 (-)Ensemblpanpan1.1panPan2
OCLN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1254,500,299 - 54,545,430 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl254,500,299 - 54,545,430 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha251,466,637 - 51,511,781 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0255,004,936 - 55,058,838 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl255,005,004 - 55,058,769 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1252,076,201 - 52,121,488 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0252,843,313 - 52,888,432 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0253,733,721 - 53,779,092 (+)NCBIUU_Cfam_GSD_1.0
Ocln
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213191,162,311 - 191,216,242 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648098,371 - 152,413 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648099,516 - 152,834 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OCLN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1647,600,212 - 47,654,033 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11647,600,175 - 47,652,435 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21651,547,473 - 51,598,116 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OCLN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1465,581,943 - 65,641,516 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl465,582,460 - 65,644,787 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604914,326,566 - 14,386,556 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000004572   ⟹   ENSHGLP00000004510
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624905333,864 - 388,880 (+)Ensembl
RefSeq Acc Id: XM_004872837   ⟹   XP_004872894
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624905333,853 - 388,990 (+)NCBI
RefSeq Acc Id: XM_004872838   ⟹   XP_004872895
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624905334,136 - 388,990 (+)NCBI
RefSeq Acc Id: XM_004872839   ⟹   XP_004872896
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624905345,032 - 388,990 (+)NCBI
RefSeq Acc Id: XM_004872840   ⟹   XP_004872897
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624905334,231 - 388,990 (+)NCBI
RefSeq Acc Id: XM_004872841   ⟹   XP_004872898
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624905333,862 - 388,990 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004872894   ⟸   XM_004872837
- Peptide Label: isoform X1
- UniProtKB: G5C0I2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004872898   ⟸   XM_004872841
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004872895   ⟸   XM_004872838
- Peptide Label: isoform X1
- UniProtKB: G5C0I2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004872897   ⟸   XM_004872840
- Peptide Label: isoform X1
- UniProtKB: G5C0I2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004872896   ⟸   XM_004872839
- Peptide Label: isoform X1
- UniProtKB: G5C0I2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000004510   ⟸   ENSHGLT00000004572


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003299 Ensembl, ENTREZGENE
  ENSHGLG00100008567 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000004572 ENTREZGENE
  ENSHGLT00100011686 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.340 UniProtKB/TrEMBL
InterPro ELL/occludin UniProtKB/TrEMBL
  Marvel UniProtKB/TrEMBL
  Occludin UniProtKB/TrEMBL
  Occludin_ELL UniProtKB/TrEMBL
KEGG Report hgl:101704116 UniProtKB/TrEMBL
NCBI Gene Ocln ENTREZGENE
PANTHER PTHR23288 UniProtKB/TrEMBL
  PTHR23288:SF4 UniProtKB/TrEMBL
Pfam MARVEL UniProtKB/TrEMBL
  Occludin_ELL UniProtKB/TrEMBL
PIRSF Occludin UniProtKB/TrEMBL
PRINTS OCCLUDIN UniProtKB/TrEMBL
PROSITE MARVEL UniProtKB/TrEMBL
  OCEL UniProtKB/TrEMBL
Superfamily-SCOP occludin/ELL-like UniProtKB/TrEMBL
UniProt G5C0I2 ENTREZGENE, UniProtKB/TrEMBL