Phip (pleckstrin homology domain interacting protein) - Rat Genome Database

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Gene: Phip (pleckstrin homology domain interacting protein) Heterocephalus glaber
Analyze
Symbol: Phip
Name: pleckstrin homology domain interacting protein
RGD ID: 18930118
Description: ENCODES a protein that exhibits lysine-acetylated histone binding (ortholog); INVOLVED IN cell population proliferation (ortholog); fibroblast proliferation (ortholog); insulin receptor signaling pathway (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND DYSMORPHIC FEATURES (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: PH-interacting protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248195,608,019 - 5,720,121 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248195,603,334 - 5,675,664 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Phip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248195,608,019 - 5,720,121 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248195,603,334 - 5,675,664 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PHIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38678,934,419 - 79,078,254 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl678,934,419 - 79,078,287 (-)EnsemblGRCh38hg38GRCh38
GRCh37679,644,136 - 79,787,971 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36679,706,985 - 79,844,708 (-)NCBINCBI36Build 36hg18NCBI36
Build 34679,707,001 - 79,844,708NCBI
Celera680,031,409 - 80,175,293 (-)NCBICelera
Cytogenetic Map6q14.1NCBI
HuRef676,837,993 - 76,981,618 (-)NCBIHuRef
CHM1_1679,741,711 - 79,885,530 (-)NCBICHM1_1
T2T-CHM13v2.0680,112,128 - 80,255,969 (-)NCBIT2T-CHM13v2.0
Phip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39982,748,212 - 82,857,776 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl982,748,212 - 82,857,569 (-)EnsemblGRCm39 Ensembl
GRCm38982,866,159 - 82,981,668 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl982,866,159 - 82,975,516 (-)EnsemblGRCm38mm10GRCm38
MGSCv37982,759,766 - 82,869,096 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36982,662,877 - 82,772,207 (-)NCBIMGSCv36mm8
Celera979,960,082 - 80,068,701 (-)NCBICelera
Cytogenetic Map9E2NCBI
cM Map945.18NCBI
Phip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8892,656,890 - 92,771,098 (-)NCBIGRCr8
mRatBN7.2883,776,802 - 83,891,192 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl883,781,465 - 83,894,283 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0890,387,339 - 90,483,964 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl890,392,143 - 90,483,077 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0889,916,080 - 90,014,067 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4888,009,896 - 88,060,553 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera883,437,217 - 83,536,036 (-)NCBICelera
Cytogenetic Map8q31NCBI
Phip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555026,842,149 - 6,935,263 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555026,842,149 - 6,951,791 (-)NCBIChiLan1.0ChiLan1.0
PHIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2598,989,992 - 99,133,659 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1696,872,217 - 97,014,485 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0676,785,886 - 76,929,475 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1680,058,059 - 80,186,787 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl680,064,340 - 80,184,036 (-)Ensemblpanpan1.1panPan2
PHIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11239,899,738 - 40,015,795 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1239,904,603 - 40,032,194 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1239,773,107 - 39,905,224 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01240,671,860 - 40,803,758 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1240,674,679 - 40,803,670 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11239,993,134 - 40,125,018 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01239,971,723 - 40,103,648 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01240,102,603 - 40,234,495 (-)NCBIUU_Cfam_GSD_1.0
Phip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494675,272,412 - 75,394,105 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651011,076,785 - 11,193,689 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651011,076,790 - 11,198,483 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl187,117,092 - 87,243,675 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1187,116,884 - 87,247,500 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2197,888,778 - 98,018,039 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PHIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1133,646,331 - 3,783,930 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl133,651,161 - 3,783,160 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040179,872,537 - 180,010,986 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000001446   ⟹   ENSHGLP00000001403
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248195,608,019 - 5,720,121 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000001447   ⟹   ENSHGLP00000001404
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248195,673,126 - 5,705,028 (-)Ensembl
RefSeq Acc Id: XM_021243784   ⟹   XP_021099443
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248195,603,334 - 5,675,664 (-)NCBI
RefSeq Acc Id: XM_021243785   ⟹   XP_021099444
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248195,603,334 - 5,675,626 (-)NCBI
RefSeq Acc Id: XM_021243786   ⟹   XP_021099445
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248195,608,019 - 5,675,626 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021099443 (Get FASTA)   NCBI Sequence Viewer  
  XP_021099444 (Get FASTA)   NCBI Sequence Viewer  
  XP_021099445 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000001403
Reference Protein Sequences
RefSeq Acc Id: XP_021099443   ⟸   XM_021243784
- Peptide Label: isoform X1
- UniProtKB: G5BC11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099444   ⟸   XM_021243785
- Peptide Label: isoform X2
- UniProtKB: G5BC11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099445   ⟸   XM_021243786
- Peptide Label: isoform X3
- UniProtKB: G5BC11 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000001404   ⟸   ENSHGLT00000001447
RefSeq Acc Id: ENSHGLP00000001403   ⟸   ENSHGLT00000001446


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001086 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000001446 ENTREZGENE
Gene3D-CATH Bromodomain-like UniProtKB/TrEMBL
  YVTN repeat-like/Quinoprotein amine dehydrogenase UniProtKB/TrEMBL
InterPro Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  Bromodomain_CS UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Phip ENTREZGENE
PANTHER BRWD3 UniProtKB/TrEMBL
  WD REPEAT DOMAIN 9 UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_1 UniProtKB/TrEMBL
  BROMODOMAIN_2 UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART BROMO UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP Bromodomain UniProtKB/TrEMBL
  WD40 repeat-like UniProtKB/TrEMBL
UniProt G5BC11 ENTREZGENE, UniProtKB/TrEMBL