Ssb (small RNA binding exonuclease protection factor La) - Rat Genome Database

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Gene: Ssb (small RNA binding exonuclease protection factor La) Heterocephalus glaber
Analyze
Symbol: Ssb
Name: small RNA binding exonuclease protection factor La
RGD ID: 18924262
Description: ENCODES a protein that exhibits poly(U) RNA binding (ortholog); sequence-specific mRNA binding (ortholog); tRNA binding (ortholog); INVOLVED IN IRES-dependent viral translational initiation (ortholog); nuclear histone mRNA catabolic process (ortholog); protein localization to cytoplasmic stress granule (ortholog); PARTICIPATES IN tRNA maturation pathway; ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Lupus La protein; Sjogren syndrome antigen B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247877,292,549 - 7,301,190 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ssb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247877,292,549 - 7,301,190 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SSB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382169,798,871 - 169,812,064 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2169,791,933 - 169,812,064 (+)EnsemblGRCh38hg38GRCh38
GRCh372170,655,381 - 170,668,574 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362170,363,635 - 170,376,821 (+)NCBINCBI36Build 36hg18NCBI36
Build 342170,480,895 - 170,494,082NCBI
Celera2164,271,755 - 164,284,947 (+)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2162,543,375 - 162,556,636 (+)NCBIHuRef
CHM1_12170,659,176 - 170,674,430 (+)NCBICHM1_1
T2T-CHM13v2.02170,276,405 - 170,289,608 (+)NCBIT2T-CHM13v2.0
Ssb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39269,691,963 - 69,702,185 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl269,691,906 - 69,702,190 (+)EnsemblGRCm39 Ensembl
GRCm38269,861,562 - 69,871,846 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl269,861,562 - 69,871,846 (+)EnsemblGRCm38mm10GRCm38
MGSCv37269,699,619 - 69,709,903 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36269,662,467 - 69,672,643 (+)NCBIMGSCv36mm8
Celera271,531,605 - 71,541,890 (+)NCBICelera
Cytogenetic Map2C2NCBI
cM Map240.95NCBI
Ssb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8375,024,385 - 75,034,016 (+)NCBIGRCr8
mRatBN7.2354,616,616 - 54,626,203 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl354,616,619 - 54,626,203 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx358,018,226 - 58,027,720 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0366,601,821 - 66,611,315 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0364,364,199 - 64,373,694 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0356,092,425 - 56,102,008 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl356,092,501 - 56,102,001 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0362,727,433 - 62,737,034 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4352,001,106 - 52,010,611 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1351,897,477 - 51,906,978 (+)NCBI
Celera354,176,184 - 54,185,689 (+)NCBICelera
Cytogenetic Map3q21NCBI
Ssb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554494,806,468 - 4,815,175 (-)NCBIChiLan1.0ChiLan1.0
SSB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21372,459,193 - 72,472,464 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B72,474,165 - 72,487,436 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B57,071,158 - 57,084,428 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B174,536,382 - 174,549,609 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B174,536,382 - 174,549,604 (+)Ensemblpanpan1.1panPan2
SSB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13614,465,088 - 14,476,786 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3614,465,129 - 14,476,609 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3614,477,215 - 14,488,515 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03614,584,035 - 14,595,782 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3614,584,083 - 14,597,032 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13614,667,144 - 14,678,600 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03614,659,402 - 14,670,867 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03614,770,849 - 14,782,579 (+)NCBIUU_Cfam_GSD_1.0
Ssb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303131,732,490 - 131,741,876 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936509286,398 - 298,147 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936509286,397 - 295,779 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SSB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1576,088,641 - 76,100,785 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11576,088,587 - 76,099,517 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21585,205,395 - 85,216,312 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SSB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11055,325,975 - 55,339,317 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1055,262,897 - 55,339,008 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040144,196,826 - 144,210,322 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004857644   ⟹   XP_004857701
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247877,292,549 - 7,301,190 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004857701 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB17910 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024656
  ENSHGLP00100004044
GenBank Protein JAO03335 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004857701   ⟸   XM_004857644
- UniProtKB: G5C8P9 (UniProtKB/TrEMBL),   G5B250 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017580 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100003084 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000024878 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00100004109 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro La_dom_prot UniProtKB/TrEMBL
  La_HTH UniProtKB/TrEMBL
  La_xRRM UniProtKB/TrEMBL
  Lupus_La UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report hgl:101724484 UniProtKB/TrEMBL
NCBI Gene Ssb ENTREZGENE
PANTHER LUPUS LA PROTEIN HOMOLOG UniProtKB/TrEMBL
  PTHR22792 UniProtKB/TrEMBL
Pfam PF05383 UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
  RRM_3 UniProtKB/TrEMBL
PRINTS LUPUSLA UniProtKB/TrEMBL
PROSITE HTH_LA UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
  XRRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
  SM00715 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt G5B250 ENTREZGENE, UniProtKB/TrEMBL
  G5C8P9 ENTREZGENE, UniProtKB/TrEMBL