Slc25a22 (solute carrier family 25 member 22) - Rat Genome Database

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Gene: Slc25a22 (solute carrier family 25 member 22) Heterocephalus glaber
Analyze
Symbol: Slc25a22
Name: solute carrier family 25 member 22
RGD ID: 18922998
Description: ENCODES a protein that exhibits amino acid:proton symporter activity (inferred); L-aspartate transmembrane transporter activity (inferred); L-glutamate transmembrane transporter activity (inferred); INVOLVED IN regulation of insulin secretion (ortholog); ASSOCIATED WITH Chanarin-Dorfman syndrome (ortholog); delta beta-thalassemia (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitochondrial glutamate carrier 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476621,712,907 - 21,717,724 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476621,710,867 - 21,717,724 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Slc25a22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476621,712,907 - 21,717,724 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476621,710,867 - 21,717,724 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SLC25A22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811790,475 - 798,281 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11790,475 - 798,281 (-)EnsemblGRCh38hg38GRCh38
GRCh3711790,475 - 798,281 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611780,475 - 786,221 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411780,475 - 786,221NCBI
Celera11857,022 - 864,848 (-)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11607,241 - 615,035 (-)NCBIHuRef
CHM1_111789,304 - 797,176 (-)NCBICHM1_1
T2T-CHM13v2.011841,908 - 849,743 (-)NCBIT2T-CHM13v2.0
Slc25a22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,009,662 - 141,017,787 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7141,009,657 - 141,017,805 (-)EnsemblGRCm39 Ensembl
GRCm387141,429,749 - 141,437,874 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,429,744 - 141,437,892 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,615,648 - 148,623,773 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367141,281,072 - 141,288,938 (-)NCBIMGSCv36mm8
Celera7141,223,495 - 141,231,620 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.78NCBI
Slc25a22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81205,954,713 - 205,966,188 (-)NCBIGRCr8
mRatBN7.21196,528,471 - 196,536,398 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,528,472 - 196,536,331 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1204,873,948 - 204,881,790 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,002,439 - 212,010,289 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01204,676,577 - 204,684,427 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01214,410,388 - 214,418,236 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,410,417 - 214,414,897 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,973,489 - 213,981,330 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,890,711 - 220,898,559 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,617,689 - 201,625,537 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11201,771,046 - 201,778,892 (-)NCBI
Celera1194,161,971 - 194,169,815 (-)NCBICelera
Cytogenetic Map1q41NCBI
Slc25a22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,334,507 - 11,338,835 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,334,508 - 11,338,781 (+)NCBIChiLan1.0ChiLan1.0
SLC25A22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v293,188,033 - 3,195,917 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,397,980 - 2,405,864 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011807,886 - 815,770 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111851,998 - 859,866 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11851,998 - 858,121 (-)Ensemblpanpan1.1panPan2
SLC25A22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha1825,457,395 - 25,461,785 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01826,393,071 - 26,397,455 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11825,902,573 - 25,906,925 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01825,547,588 - 25,551,985 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01826,159,899 - 26,164,289 (-)NCBIUU_Cfam_GSD_1.0
Slc25a22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947558,059 - 565,623 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936888558,045 - 565,782 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936888558,064 - 565,576 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2491,293 - 498,767 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12491,288 - 498,773 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22175,568 - 183,079 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11593,914 - 601,603 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1593,890 - 598,585 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,666,665 - 97,693,953 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000006763   ⟹   ENSHGLP00000006681
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476621,712,907 - 21,717,724 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000006764   ⟹   ENSHGLP00000006682
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476621,715,935 - 21,716,298 (+)Ensembl
RefSeq Acc Id: XM_004851682   ⟹   XP_004851739
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,712,906 - 21,717,724 (+)NCBI
RefSeq Acc Id: XM_004851683   ⟹   XP_004851740
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,712,550 - 21,717,724 (+)NCBI
RefSeq Acc Id: XM_021264038   ⟹   XP_021119697
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,711,571 - 21,717,724 (+)NCBI
RefSeq Acc Id: XM_021264039   ⟹   XP_021119698
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,711,252 - 21,717,724 (+)NCBI
RefSeq Acc Id: XM_021264040   ⟹   XP_021119699
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,710,867 - 21,717,724 (+)NCBI
RefSeq Acc Id: XM_021264041   ⟹   XP_021119700
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476621,711,570 - 21,717,724 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021119699   ⟸   XM_021264040
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J4Z6 (UniProtKB/TrEMBL),   G5C8G6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119698   ⟸   XM_021264039
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J4Z6 (UniProtKB/TrEMBL),   G5C8G6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119700   ⟸   XM_021264041
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021119697   ⟸   XM_021264038
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J4Z6 (UniProtKB/TrEMBL),   G5C8G6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851740   ⟸   XM_004851683
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J4Z6 (UniProtKB/TrEMBL),   G5C8G6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851739   ⟸   XM_004851682
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J4Z6 (UniProtKB/TrEMBL),   G5C8G6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000006681   ⟸   ENSHGLT00000006763
RefSeq Acc Id: ENSHGLP00000006682   ⟸   ENSHGLT00000006764


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004879 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000006763 ENTREZGENE
Gene3D-CATH 1.50.40.10 UniProtKB/TrEMBL
InterPro Mit_carrier UniProtKB/TrEMBL
  Mitochondrial_sb/sol_carrier UniProtKB/TrEMBL
  Mt_carrier_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101703740 UniProtKB/TrEMBL
NCBI Gene Slc25a22 ENTREZGENE
PANTHER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED UniProtKB/TrEMBL
  MITOCHONDRIAL GLUTAMATE CARRIER 1 UniProtKB/TrEMBL
Pfam Mito_carr UniProtKB/TrEMBL
PRINTS MITOCARRIER UniProtKB/TrEMBL
PROSITE SOLCAR UniProtKB/TrEMBL
Superfamily-SCOP SSF103506 UniProtKB/TrEMBL
UniProt A0A0P6J4Z6 ENTREZGENE, UniProtKB/TrEMBL
  G5C8G6 ENTREZGENE, UniProtKB/TrEMBL