Mtss2 (MTSS I-BAR domain containing 2) - Rat Genome Database

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Gene: Mtss2 (MTSS I-BAR domain containing 2) Heterocephalus glaber
Analyze
Symbol: Mtss2
Name: MTSS I-BAR domain containing 2
RGD ID: 18921153
Description: ENCODES a protein that exhibits actin binding (inferred); actin monomer binding (inferred); GTPase activator activity (inferred); INVOLVED IN lamellipodium organization (ortholog); membrane organization (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); Developmental Disabilities (ortholog); intellectual developmental disorder with ocular anomalies and distinctive facial features (ortholog); FOUND IN actin cytoskeleton (inferred); cortical actin cytoskeleton (inferred); lamellipodium (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MTSS1-like protein; Mtss1l; MTSS1L, I-BAR domain containing
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474612,867,679 - 12,887,578 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474612,868,006 - 12,887,616 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mtss2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474612,867,679 - 12,887,578 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474612,868,006 - 12,887,616 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MTSS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381670,661,204 - 70,686,053 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1670,661,204 - 70,686,053 (-)EnsemblGRCh38hg38GRCh38
GRCh371670,695,107 - 70,719,956 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361669,252,608 - 69,277,455 (-)NCBINCBI36Build 36hg18NCBI36
Celera1654,809,225 - 54,829,060 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1656,526,534 - 56,581,668 (-)NCBIHuRef
CHM1_11672,102,447 - 72,127,306 (-)NCBICHM1_1
T2T-CHM13v2.01676,472,385 - 76,497,224 (-)NCBIT2T-CHM13v2.0
Mtss2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398111,447,718 - 111,468,032 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8111,448,108 - 111,468,032 (+)EnsemblGRCm39 Ensembl
GRCm388110,721,108 - 110,741,401 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8110,721,476 - 110,741,400 (+)EnsemblGRCm38mm10GRCm38
MGSCv378113,245,384 - 113,265,300 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368113,608,161 - 113,628,077 (+)NCBIMGSCv36mm8
Celera8114,950,022 - 114,965,339 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map857.66NCBI
Mtss2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,602,180 - 55,623,955 (+)NCBIGRCr8
mRatBN7.21938,692,793 - 38,714,575 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,693,194 - 38,713,507 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1945,498,974 - 45,518,694 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,152,341 - 46,172,062 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01948,462,871 - 48,482,629 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01940,904,779 - 40,925,660 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1940,905,847 - 40,925,660 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01951,730,106 - 51,745,921 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,640,947 - 40,661,240 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11940,645,827 - 40,664,822 (+)NCBI
Celera1938,091,799 - 38,107,220 (+)NCBICelera
Cytogenetic Map19q12NCBI
Mtss2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554843,429,474 - 3,445,446 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554843,429,474 - 3,445,429 (-)NCBIChiLan1.0ChiLan1.0
MTSS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21883,480,385 - 83,505,200 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11689,414,046 - 89,438,809 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01654,331,300 - 54,338,656 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11670,495,435 - 70,517,660 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1670,497,625 - 70,514,716 (-)Ensemblpanpan1.1panPan2
MTSS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1576,613,388 - 76,633,873 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl576,614,570 - 76,629,867 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha576,574,111 - 76,595,255 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0577,049,543 - 77,071,125 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl577,051,714 - 77,071,072 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1576,871,393 - 76,892,916 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0576,694,202 - 76,715,351 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0577,185,864 - 77,207,451 (-)NCBIUU_Cfam_GSD_1.0
Mtss2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934936,621,630 - 36,638,267 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647522,950,793 - 22,967,467 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647522,948,608 - 22,967,489 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTSS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl613,660,392 - 13,682,316 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1613,660,388 - 13,682,311 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2613,507,386 - 13,509,829 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTSS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1553,802,594 - 53,827,763 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl553,805,020 - 53,827,648 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604716,614,698 - 16,639,929 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000013717   ⟹   ENSHGLP00000013576
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474612,867,679 - 12,887,578 (-)Ensembl
RefSeq Acc Id: XM_004842884   ⟹   XP_004842941
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474612,868,006 - 12,887,615 (-)NCBI
RefSeq Acc Id: XM_004842885   ⟹   XP_004842942
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474612,868,006 - 12,887,615 (-)NCBI
RefSeq Acc Id: XM_013071498   ⟹   XP_012926952
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474612,868,006 - 12,887,615 (-)NCBI
RefSeq Acc Id: XM_013071499   ⟹   XP_012926953
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474612,868,006 - 12,887,615 (-)NCBI
RefSeq Acc Id: XM_013071500   ⟹   XP_012926954
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474612,868,006 - 12,881,493 (-)NCBI
RefSeq Acc Id: XM_021256713   ⟹   XP_021112372
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474612,868,006 - 12,887,616 (-)NCBI
RefSeq Acc Id: XM_021256714   ⟹   XP_021112373
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474612,868,006 - 12,887,616 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021112373   ⟸   XM_021256714
- Peptide Label: isoform X6
- UniProtKB: G5C1Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112372   ⟸   XM_021256713
- Peptide Label: isoform X3
- UniProtKB: G5C1Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842942   ⟸   XM_004842885
- Peptide Label: isoform X5
- UniProtKB: G5C1Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926952   ⟸   XM_013071498
- Peptide Label: isoform X2
- UniProtKB: G5C1Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926953   ⟸   XM_013071499
- Peptide Label: isoform X4
- UniProtKB: G5C1Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842941   ⟸   XM_004842884
- Peptide Label: isoform X1
- UniProtKB: A0A0P6K1Z1 (UniProtKB/TrEMBL),   G5C1Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926954   ⟸   XM_013071500
- Peptide Label: isoform X7
- UniProtKB: G5C1Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000013576   ⟸   ENSHGLT00000013717


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009708 Ensembl, ENTREZGENE
  ENSHGLG00000046719 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000013717 ENTREZGENE
  ENSHGLT00000060020 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/TrEMBL
  I-BAR_dom UniProtKB/TrEMBL
  MTSS1/MTSS2 UniProtKB/TrEMBL
KEGG Report hgl:101723552 UniProtKB/TrEMBL
NCBI Gene Mtss2 ENTREZGENE
PANTHER PTHR15708 UniProtKB/TrEMBL
  PTHR15708:SF8 UniProtKB/TrEMBL
Pfam IMD UniProtKB/TrEMBL
PROSITE IMD UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/TrEMBL
UniProt A0A0P6K1Z1 ENTREZGENE, UniProtKB/TrEMBL
  G5C1Q2 ENTREZGENE, UniProtKB/TrEMBL