Gzmk (granzyme K) - Rat Genome Database

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Gene: Gzmk (granzyme K) Heterocephalus glaber
Analyze
Symbol: Gzmk
Name: granzyme K
RGD ID: 18921117
Description: ENCODES a protein that exhibits serine-type peptidase activity (ortholog); INVOLVED IN positive regulation of apoptotic process (inferred); proteolysis (inferred); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247594,270,960 - 4,280,257 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247594,270,922 - 4,280,257 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Gzmk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247594,270,960 - 4,280,257 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247594,270,922 - 4,280,257 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
GZMK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38555,024,256 - 55,034,570 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl555,024,256 - 55,034,570 (+)EnsemblGRCh38hg38GRCh38
GRCh37554,320,084 - 54,330,398 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36554,355,864 - 54,365,717 (+)NCBINCBI36Build 36hg18NCBI36
Build 34554,355,867 - 54,365,716NCBI
Celera551,273,297 - 51,283,152 (+)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef551,293,685 - 51,303,533 (+)NCBIHuRef
CHM1_1554,323,348 - 54,333,196 (+)NCBICHM1_1
T2T-CHM13v2.0555,851,867 - 55,862,179 (+)NCBIT2T-CHM13v2.0
Gzmk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913113,308,164 - 113,317,499 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13113,308,142 - 113,362,442 (-)EnsemblGRCm39 Ensembl
GRCm3813113,171,630 - 113,180,965 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13113,171,608 - 113,225,908 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713113,962,082 - 113,971,105 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613114,292,752 - 114,301,775 (-)NCBIMGSCv36mm8
Celera13117,491,279 - 117,500,126 (-)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1363.93NCBI
Gzmk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8246,573,997 - 46,582,015 (-)NCBIGRCr8
mRatBN7.2244,840,811 - 44,848,829 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl244,840,811 - 44,848,894 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx251,945,501 - 51,953,571 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0250,003,858 - 50,011,926 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0244,883,933 - 44,892,005 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0245,069,136 - 45,077,154 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl245,068,967 - 45,077,219 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0264,101,925 - 64,109,992 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4244,589,295 - 44,597,386 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1244,517,527 - 44,525,619 (-)NCBI
Celera240,611,754 - 40,619,756 (-)NCBICelera
Cytogenetic Map2q14NCBI
Gzmk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544612,620,229 - 12,633,574 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544612,623,257 - 12,633,584 (-)NCBIChiLan1.0ChiLan1.0
GZMK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2458,905,617 - 58,916,296 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1557,059,242 - 57,069,833 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0558,995,144 - 59,005,257 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1560,616,968 - 60,626,834 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl560,616,730 - 60,627,150 (-)Ensemblpanpan1.1panPan2
GZMK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1460,559,234 - 60,569,178 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl460,559,216 - 60,569,533 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha460,323,403 - 60,333,358 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0461,047,873 - 61,057,828 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl461,047,885 - 61,057,844 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1460,827,952 - 60,837,905 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0460,954,735 - 60,964,688 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0461,472,808 - 61,482,765 (-)NCBIUU_Cfam_GSD_1.0
Gzmk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213203,784,096 - 203,788,266 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648012,720,661 - 12,730,905 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648012,720,873 - 12,730,832 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GZMK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1634,217,303 - 34,226,338 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11634,217,339 - 34,226,139 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21636,215,916 - 36,329,677 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GZMK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1451,270,564 - 51,280,447 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl451,270,612 - 51,280,447 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666049137,205 - 147,080 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000007325   ⟹   ENSHGLP00000007240
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247594,270,960 - 4,280,257 (-)Ensembl
RefSeq Acc Id: XM_004848679   ⟹   XP_004848736
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247594,270,922 - 4,280,257 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004848736 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB17287 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000007240
  ENSHGLP00100024570
Reference Protein Sequences
RefSeq Acc Id: XP_004848736   ⟸   XM_004848679
- UniProtKB: G5C6X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000007240   ⟸   ENSHGLT00000007325


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005273 Ensembl, ENTREZGENE
  ENSHGLG00100018045 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000007325 ENTREZGENE
  ENSHGLT00100024822 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
KEGG Report hgl:101707104 UniProtKB/TrEMBL
NCBI Gene Gzmk ENTREZGENE
PANTHER GRANZYME K UniProtKB/TrEMBL
  KALLIKREIN-RELATED UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt G5C6X6 ENTREZGENE, UniProtKB/TrEMBL