Unc45a (unc-45 myosin chaperone A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Unc45a (unc-45 myosin chaperone A) Heterocephalus glaber
Analyze
Symbol: Unc45a
Name: unc-45 myosin chaperone A
RGD ID: 18920568
Description: ENCODES a protein that exhibits Hsp90 protein binding (inferred); INVOLVED IN chaperone-mediated protein folding (ortholog); ASSOCIATED WITH Aagenaes syndrome (ortholog); Bloom syndrome (ortholog); D-2-hydroxyglutaric aciduria 2 (ortholog); FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); nuclear speck (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein unc-45 homolog A; unc-45 homolog A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476817,301,277 - 17,314,353 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476817,300,913 - 17,315,848 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Unc45a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476817,301,277 - 17,314,353 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476817,300,913 - 17,315,848 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
UNC45A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381590,930,180 - 90,954,093 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1590,930,180 - 90,954,093 (+)EnsemblGRCh38hg38GRCh38
GRCh371591,473,410 - 91,497,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361589,274,414 - 89,298,327 (+)NCBINCBI36Build 36hg18NCBI36
Celera1567,882,608 - 67,906,541 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1567,584,693 - 67,608,337 (+)NCBIHuRef
CHM1_11591,315,008 - 91,338,915 (+)NCBICHM1_1
T2T-CHM13v2.01588,689,763 - 88,713,676 (+)NCBIT2T-CHM13v2.0
Unc45a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,975,040 - 79,990,748 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl779,975,040 - 79,997,741 (-)EnsemblGRCm39 Ensembl
GRCm38780,325,292 - 80,341,000 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl780,325,292 - 80,347,993 (-)EnsemblGRCm38mm10GRCm38
MGSCv37787,470,178 - 87,485,105 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36780,198,805 - 80,213,721 (-)NCBIMGSCv36mm8
Celera777,726,922 - 77,741,669 (-)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.65NCBI
Unc45a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81143,691,183 - 143,705,944 (-)NCBIGRCr8
mRatBN7.21134,281,930 - 134,296,661 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1134,281,933 - 134,301,586 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1142,190,794 - 142,205,526 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01149,360,192 - 149,374,924 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01142,278,055 - 142,292,760 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01142,118,910 - 142,135,219 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1142,118,917 - 142,133,627 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01143,071,169 - 143,086,070 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,143,883 - 136,158,600 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11136,222,638 - 136,236,882 (-)NCBI
Celera1126,341,954 - 126,356,671 (-)NCBICelera
Cytogenetic Map1q31NCBI
Unc45a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541614,999,375 - 15,012,581 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541614,999,692 - 15,012,581 (+)NCBIChiLan1.0ChiLan1.0
UNC45A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21680,488,659 - 80,507,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11584,186,632 - 84,206,564 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01569,623,199 - 69,647,468 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11588,820,455 - 88,844,502 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1588,820,444 - 88,844,502 (+)Ensemblpanpan1.1panPan2
UNC45A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1353,294,628 - 53,307,759 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl353,295,197 - 53,309,067 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,932,260 - 55,945,409 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0353,710,644 - 53,723,802 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl353,710,647 - 53,726,313 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1353,229,894 - 53,243,047 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0353,441,012 - 53,454,165 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0353,781,508 - 53,794,661 (-)NCBIUU_Cfam_GSD_1.0
Unc45a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640130,246,227 - 130,262,098 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648316,072,663 - 16,087,218 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648316,072,421 - 16,087,286 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC45A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl753,522,474 - 53,545,960 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1753,530,914 - 53,545,960 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2758,562,136 - 58,577,155 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UNC45A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1298,908,381 - 8,932,555 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl298,908,141 - 8,923,031 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605937,793,482 - 37,817,656 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000016870   ⟹   ENSHGLP00000016699
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476817,301,277 - 17,314,353 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000016871   ⟹   ENSHGLP00000016700
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476817,313,554 - 17,314,353 (-)Ensembl
RefSeq Acc Id: XM_004852802   ⟹   XP_004852859
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476817,300,913 - 17,315,848 (-)NCBI
RefSeq Acc Id: XM_021264831   ⟹   XP_021120490
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476817,300,913 - 17,314,122 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004852859 (Get FASTA)   NCBI Sequence Viewer  
  XP_021120490 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000016699
GenBank Protein JAN97774 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004852859   ⟸   XM_004852802
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JU88 (UniProtKB/TrEMBL),   G5CAB3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120490   ⟸   XM_021264831
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000016700   ⟸   ENSHGLT00000016871
RefSeq Acc Id: ENSHGLP00000016699   ⟸   ENSHGLT00000016870


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011948 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000016870 ENTREZGENE
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  1.25.40.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
  UCS_central_dom UniProtKB/TrEMBL
KEGG Report hgl:101715722 UniProtKB/TrEMBL
NCBI Gene Unc45a ENTREZGENE
PANTHER FI21225P1 UniProtKB/TrEMBL
  PROTEIN UNC-45 HOMOLOG A UniProtKB/TrEMBL
Pfam TPR_16 UniProtKB/TrEMBL
  TPR_8 UniProtKB/TrEMBL
  UNC45-central UniProtKB/TrEMBL
PROSITE TPR UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
UniProt A0A0P6JU88 ENTREZGENE, UniProtKB/TrEMBL
  G5CAB3 ENTREZGENE, UniProtKB/TrEMBL