Eif5b (eukaryotic translation initiation factor 5B) - Rat Genome Database

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Gene: Eif5b (eukaryotic translation initiation factor 5B) Heterocephalus glaber
Analyze
Symbol: Eif5b
Name: eukaryotic translation initiation factor 5B
RGD ID: 18920482
Description: ENCODES a protein that exhibits tRNA binding (ortholog); INVOLVED IN regulation of translational initiation (ortholog); ribosome assembly (ortholog); PARTICIPATES IN translation initiation pathway; FOUND IN nucleus (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247494,297,667 - 4,373,918 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247494,297,832 - 4,373,918 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
mitochondrion  (IEA)
nucleus  (ISO)
synapse  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Eif5b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247494,297,667 - 4,373,918 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247494,297,832 - 4,373,918 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
EIF5B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38299,337,389 - 99,401,326 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl299,337,389 - 99,401,326 (+)EnsemblGRCh38hg38GRCh38
GRCh37299,953,852 - 100,017,789 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36299,320,266 - 99,383,160 (+)NCBINCBI36Build 36hg18NCBI36
Build 34299,412,394 - 99,474,760NCBI
Celera294,158,503 - 94,221,412 (+)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef293,719,194 - 93,782,572 (+)NCBIHuRef
CHM1_1299,958,605 - 100,021,494 (+)NCBICHM1_1
T2T-CHM13v2.0299,796,021 - 99,859,976 (+)NCBIT2T-CHM13v2.0
Eif5b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39138,037,091 - 38,094,660 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl138,037,091 - 38,094,660 (+)EnsemblGRCm39 Ensembl
GRCm38137,998,010 - 38,055,579 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl137,998,010 - 38,055,579 (+)EnsemblGRCm38mm10GRCm38
MGSCv37138,054,855 - 38,112,424 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36137,942,556 - 38,000,125 (+)NCBIMGSCv36mm8
Celera137,775,604 - 37,832,998 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map116.4NCBI
Eif5b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8947,718,706 - 47,773,289 (+)NCBIGRCr8
mRatBN7.2940,222,769 - 40,277,482 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl940,222,898 - 40,277,482 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx948,718,560 - 48,773,198 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0953,841,325 - 53,895,960 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0952,123,621 - 52,178,205 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0944,658,724 - 44,713,518 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl944,681,494 - 44,713,199 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0944,354,546 - 44,409,587 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4936,937,415 - 36,993,650 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1936,963,310 - 36,966,045 (+)NCBI
Celera937,976,326 - 38,029,828 (+)NCBICelera
Cytogenetic Map9q21NCBI
Eif5b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554705,622,128 - 5,676,533 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554705,622,128 - 5,676,533 (+)NCBIChiLan1.0ChiLan1.0
EIF5B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21229,031,310 - 29,093,502 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A29,034,070 - 29,096,197 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A99,898,341 - 99,960,829 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A100,266,800 - 100,328,837 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A100,289,562 - 100,328,470 (+)Ensemblpanpan1.1panPan2
EIF5B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11043,247,536 - 43,342,754 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1043,244,704 - 43,342,575 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1043,171,425 - 43,266,587 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01044,117,126 - 44,212,388 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1044,118,093 - 44,212,219 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11043,830,346 - 43,925,445 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01044,112,733 - 44,207,859 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01044,295,141 - 44,390,392 (-)NCBIUU_Cfam_GSD_1.0
Eif5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629285,116,933 - 85,170,825 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366611,394,738 - 1,452,640 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366611,398,526 - 1,452,530 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF5B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl354,861,758 - 54,905,810 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1354,861,759 - 54,930,826 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2357,499,007 - 57,566,154 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EIF5B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1143,066,147 - 3,128,498 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl143,066,150 - 3,127,861 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041170,666,757 - 170,729,411 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000023161   ⟹   ENSHGLP00000022947
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247494,297,667 - 4,373,918 (+)Ensembl
RefSeq Acc Id: XM_004844429   ⟹   XP_004844486
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247494,297,832 - 4,373,918 (+)NCBI
RefSeq Acc Id: XM_021258080   ⟹   XP_021113739
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247494,297,832 - 4,373,918 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004844486 (Get FASTA)   NCBI Sequence Viewer  
  XP_021113739 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000022947
Reference Protein Sequences
RefSeq Acc Id: XP_021113739   ⟸   XM_021258080
- Peptide Label: isoform X1
- UniProtKB: G5BMS4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004844486   ⟸   XM_004844429
- Peptide Label: isoform X2
- UniProtKB: G5BMS4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000022947   ⟸   ENSHGLT00000023161


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016367 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000023161 ENTREZGENE
Gene3D-CATH P-loop containing nucleotide triphosphate hydrolases UniProtKB/TrEMBL
  Translation factors UniProtKB/TrEMBL
  Translation initiation factor IF- 2, domain 3 UniProtKB/TrEMBL
InterPro EFTU-type UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  T_Tr_GTP-bd_dom UniProtKB/TrEMBL
  TIF_IF2 UniProtKB/TrEMBL
  TIF_IF2_dom3 UniProtKB/TrEMBL
  TIF_IF2_dom3_sf UniProtKB/TrEMBL
  Transl_B-barrel_sf UniProtKB/TrEMBL
NCBI Gene Eif5b ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 5B UniProtKB/TrEMBL
  TRANSLATION INITIATION FACTOR IF-2-RELATED UniProtKB/TrEMBL
Pfam GTP_EFTU UniProtKB/TrEMBL
  GTP_EFTU_D4 UniProtKB/TrEMBL
  IF-2 UniProtKB/TrEMBL
PRINTS ELONGATNFCT UniProtKB/TrEMBL
PROSITE G_TR_2 UniProtKB/TrEMBL
Superfamily-SCOP Initiation factor IF2/eIF5b, domain 3 UniProtKB/TrEMBL
  P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
  Translation proteins UniProtKB/TrEMBL
UniProt G5BMS4 ENTREZGENE, UniProtKB/TrEMBL