Arc (activity regulated cytoskeleton associated protein) - Rat Genome Database

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Gene: Arc (activity regulated cytoskeleton associated protein) Heterocephalus glaber
Analyze
Symbol: Arc
Name: activity regulated cytoskeleton associated protein
RGD ID: 18920070
Description: ENCODES a protein that exhibits structural molecule activity (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); endoderm development (ortholog); learning (ortholog); ASSOCIATED WITH alcohol use disorder (ortholog); Alcoholic Intoxication (ortholog); Alzheimer's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); extracellular vesicle (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: activity-regulated cytoskeleton-associated protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473513,968,654 - 13,972,026 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473513,968,628 - 13,972,026 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Arc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473513,968,654 - 13,972,026 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473513,968,628 - 13,972,026 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ARC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388142,611,049 - 142,614,479 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8142,611,049 - 142,614,479 (-)EnsemblGRCh38hg38GRCh38
GRCh378143,692,410 - 143,695,840 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368143,689,412 - 143,692,835 (-)NCBINCBI36Build 36hg18NCBI36
Build 348143,689,411 - 143,692,835NCBI
Celera8140,003,980 - 140,007,899 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8138,948,085 - 138,951,389 (-)NCBIHuRef
CHM1_18143,732,641 - 143,736,069 (-)NCBICHM1_1
T2T-CHM13v2.08143,754,593 - 143,758,023 (-)NCBIT2T-CHM13v2.0
Arc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391574,540,930 - 74,544,419 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1574,540,932 - 74,544,419 (-)EnsemblGRCm39 Ensembl
GRCm381574,669,081 - 74,672,570 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1574,669,083 - 74,672,570 (-)EnsemblGRCm38mm10GRCm38
MGSCv371574,499,513 - 74,503,000 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361574,496,338 - 74,499,825 (-)NCBIMGSCv36mm8
Celera1576,173,822 - 76,177,304 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.25NCBI
Arc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87108,444,959 - 108,448,413 (-)NCBIGRCr8
mRatBN7.27106,555,968 - 106,559,697 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7106,555,785 - 106,559,378 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7108,314,166 - 108,317,612 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07110,537,836 - 110,541,282 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07110,483,777 - 110,487,223 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07115,907,097 - 115,911,059 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7115,907,097 - 115,910,541 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07115,812,499 - 115,815,958 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47112,771,937 - 112,775,381 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17112,806,166 - 112,809,611 (-)NCBI
Celera7102,957,256 - 102,960,700 (-)NCBICelera
Cytogenetic Map7q34NCBI
Arc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554541,379,998 - 1,383,414 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554541,379,998 - 1,383,414 (-)NCBIChiLan1.0ChiLan1.0
ARC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27160,047,111 - 160,050,549 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18135,570,636 - 135,574,069 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08139,320,366 - 139,323,802 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18142,365,962 - 142,369,309 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8142,367,995 - 142,369,185 (-)Ensemblpanpan1.1panPan2
ARC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11336,743,027 - 36,744,266 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1336,609,093 - 36,612,592 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,136,507 - 37,140,000 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1337,138,390 - 37,140,028 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11336,855,275 - 36,858,753 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01336,944,976 - 36,948,432 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01337,366,985 - 37,370,448 (-)NCBIUU_Cfam_GSD_1.0
Arc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053031,759,046 - 1,762,161 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364709,185,145 - 9,186,320 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364709,185,145 - 9,188,260 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl41,518,180 - 1,519,370 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.141,517,986 - 1,521,403 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ARC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18136,857,402 - 136,860,933 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8136,859,438 - 136,860,628 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660393,095,686 - 3,099,176 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000021560   ⟹   ENSHGLP00000021352
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473513,968,654 - 13,972,026 (+)Ensembl
RefSeq Acc Id: XM_004837875   ⟹   XP_004837932
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473513,968,628 - 13,972,026 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004837932 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021352
  ENSHGLP00100018215
GenBank Protein JAO03288 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004837932   ⟸   XM_004837875
- UniProtKB: A0A0P6JYH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000021352   ⟸   ENSHGLT00000021560


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015257 Ensembl, ENTREZGENE
  ENSHGLG00100013428 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000021560 ENTREZGENE
  ENSHGLT00100018405 UniProtKB/TrEMBL
InterPro Activity-reg_cytoskelet-assoc UniProtKB/TrEMBL
  Arc_C UniProtKB/TrEMBL
  Arc_capsid_dom UniProtKB/TrEMBL
  Arc_N UniProtKB/TrEMBL
KEGG Report hgl:101705961 UniProtKB/TrEMBL
NCBI Gene Arc ENTREZGENE
PANTHER ACTIVITY-REGULATED CYTOSKELETON-ASSOCIATED PROTEIN UniProtKB/TrEMBL
  PTHR15962 UniProtKB/TrEMBL
Pfam Arc_C UniProtKB/TrEMBL
  Arc_capsid_dom UniProtKB/TrEMBL
  Arc_MA UniProtKB/TrEMBL
PRINTS ARCARG31 UniProtKB/TrEMBL
UniProt A0A0P6JYH4 ENTREZGENE, UniProtKB/TrEMBL