Pfdn1 (prefoldin subunit 1) - Rat Genome Database

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Gene: Pfdn1 (prefoldin subunit 1) Heterocephalus glaber
Analyze
Symbol: Pfdn1
Name: prefoldin subunit 1
RGD ID: 18919082
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); B cell activation (ortholog); cerebellum development (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 31 (ortholog); familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (inferred); prefoldin complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474333,012,922 - 33,083,654 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474333,012,920 - 33,083,776 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pfdn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474333,012,922 - 33,083,654 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474333,012,920 - 33,083,776 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PFDN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,245,035 - 140,303,101 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,245,035 - 140,303,113 (-)EnsemblGRCh38hg38GRCh38
GRCh375139,624,620 - 139,682,686 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365139,604,819 - 139,662,873 (-)NCBINCBI36Build 36hg18NCBI36
Build 345139,604,835 - 139,662,847NCBI
Celera5135,701,310 - 135,759,316 (-)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5134,769,914 - 134,827,849 (-)NCBIHuRef
CHM1_15139,057,759 - 139,115,827 (-)NCBICHM1_1
T2T-CHM13v2.05140,770,478 - 140,828,531 (-)NCBIT2T-CHM13v2.0
Pfdn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,536,732 - 36,587,548 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,536,729 - 36,587,577 (-)EnsemblGRCm39 Ensembl
GRCm381836,403,679 - 36,454,495 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,403,676 - 36,454,524 (-)EnsemblGRCm38mm10GRCm38
MGSCv371836,563,333 - 36,614,149 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,529,653 - 36,580,469 (-)NCBIMGSCv36mm8
Celera1836,859,471 - 36,910,850 (-)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.46NCBI
Pfdn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,288,210 - 28,341,198 (-)NCBIGRCr8
mRatBN7.21828,014,145 - 28,067,148 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1828,014,145 - 28,067,064 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,141,323 - 28,194,236 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,903,409 - 28,956,326 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,238,656 - 28,291,565 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,233,987 - 29,290,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,233,987 - 29,290,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,940,034 - 28,997,334 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,043,386 - 29,096,475 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11829,070,391 - 29,138,459 (-)NCBI
Celera1827,742,853 - 27,795,443 (-)NCBICelera
Cytogenetic Map18p11NCBI
Pfdn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955418351,078 - 414,292 (+)NCBIChiLan1.0ChiLan1.0
PFDN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24135,504,946 - 135,564,989 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15133,644,503 - 133,702,578 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05135,611,791 - 135,669,895 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15141,729,128 - 141,786,822 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5141,729,128 - 141,786,822 (-)Ensemblpanpan1.1panPan2
PFDN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,454,139 - 35,519,818 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,454,404 - 35,519,725 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,557,224 - 32,588,680 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0235,909,878 - 35,975,476 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl235,907,816 - 35,975,361 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,961,926 - 33,027,195 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0233,829,331 - 33,894,632 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,582,250 - 34,647,518 (-)NCBIUU_Cfam_GSD_1.0
Pfdn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,296,230 - 152,359,310 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365319,252,216 - 9,311,581 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365319,252,195 - 9,311,531 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFDN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2142,011,063 - 142,077,925 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12142,011,568 - 142,078,000 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,954,676 - 148,021,374 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PFDN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12342,892,818 - 42,953,540 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2342,892,401 - 42,953,491 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603434,931,427 - 34,992,605 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000021143   ⟹   ENSHGLP00000020940
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474333,012,922 - 33,083,654 (-)Ensembl
RefSeq Acc Id: XM_004841859   ⟹   XP_004841916
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474333,013,249 - 33,083,775 (-)NCBI
RefSeq Acc Id: XM_021255918   ⟹   XP_021111577
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474333,012,920 - 33,083,627 (-)NCBI
RefSeq Acc Id: XM_021255919   ⟹   XP_021111578
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474333,012,920 - 33,083,776 (-)NCBI
RefSeq Acc Id: XM_021255920   ⟹   XP_021111579
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474333,012,920 - 33,083,609 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004841916 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111577 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111578 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111579 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020940
  ENSHGLP00000058432
Reference Protein Sequences
RefSeq Acc Id: XP_021111578   ⟸   XM_021255919
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021111577   ⟸   XM_021255918
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021111579   ⟸   XM_021255920
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004841916   ⟸   XM_004841859
- Peptide Label: isoform X4
- UniProtKB: A0A0N8EUW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000020940   ⟸   ENSHGLT00000021143


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014964 Ensembl, ENTREZGENE
  ENSHGLG00000035690 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000021143 ENTREZGENE
  ENSHGLT00000051515 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.370 UniProtKB/TrEMBL
InterPro PFD_beta-like UniProtKB/TrEMBL
  Prefoldin UniProtKB/TrEMBL
KEGG Report hgl:101699291 UniProtKB/TrEMBL
NCBI Gene Pfdn1 ENTREZGENE
PANTHER PREFOLDIN SUBUNIT 1 UniProtKB/TrEMBL
  PREFOLDIN SUBUNIT 1-RELATED UniProtKB/TrEMBL
Pfam Prefoldin_2 UniProtKB/TrEMBL
Superfamily-SCOP Prefoldin UniProtKB/TrEMBL
UniProt A0A0N8EUW6 ENTREZGENE, UniProtKB/TrEMBL