Efemp2 (EGF containing fibulin extracellular matrix protein 2) - Rat Genome Database

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Gene: Efemp2 (EGF containing fibulin extracellular matrix protein 2) Heterocephalus glaber
Analyze
Symbol: Efemp2
Name: EGF containing fibulin extracellular matrix protein 2
RGD ID: 18916313
Description: ENCODES a protein that exhibits heparin binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN aorta development (ortholog); aorta smooth muscle tissue morphogenesis (ortholog); artery development (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); aortic aneurysm (ortholog); aortic dissection (ortholog); FOUND IN basement membrane (ortholog); elastic fiber (ortholog); extracellular matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EGF containing fibulin like extracellular matrix protein 2; EGF-containing fibulin-like extracellular matrix protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,559,795 - 20,566,341 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476720,559,801 - 20,566,326 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Efemp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,559,795 - 20,566,341 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476720,559,801 - 20,566,326 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
EFEMP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,866,441 - 65,872,800 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,866,441 - 65,873,592 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,633,912 - 65,640,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,390,488 - 65,396,852 (-)NCBINCBI36Build 36hg18NCBI36
Build 341165,390,494 - 65,396,793NCBI
Celera1162,957,818 - 62,964,246 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1161,960,429 - 61,966,923 (-)NCBIHuRef
CHM1_11165,518,326 - 65,524,819 (-)NCBICHM1_1
T2T-CHM13v2.01165,860,912 - 65,867,272 (-)NCBIT2T-CHM13v2.0
Efemp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,523,974 - 5,532,548 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,523,982 - 5,532,545 (+)EnsemblGRCm39 Ensembl
GRCm38195,473,946 - 5,482,520 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,473,954 - 5,482,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv37195,474,690 - 5,481,854 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,474,750 - 5,481,853 (+)NCBIMGSCv36mm8
Celera195,346,431 - 5,353,554 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.33NCBI
Efemp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,211,057 - 212,218,739 (+)NCBIGRCr8
mRatBN7.21202,781,692 - 202,789,784 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1202,781,665 - 202,789,414 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,134,675 - 211,141,697 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,227,788 - 218,234,806 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,918,833 - 210,925,850 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,853,695 - 220,861,420 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,854,403 - 220,861,420 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,783,038 - 227,790,741 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,118,537 - 208,125,490 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11208,271,989 - 208,278,942 (+)NCBI
Celera1200,318,443 - 200,324,890 (+)NCBICelera
Cytogenetic Map1q43NCBI
Efemp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,463,987 - 19,470,605 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,463,090 - 19,470,605 (+)NCBIChiLan1.0ChiLan1.0
EFEMP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2967,095,002 - 67,101,456 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11168,137,810 - 68,144,973 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,226,755 - 61,233,181 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,555,877 - 64,561,950 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,555,877 - 64,561,950 (-)Ensemblpanpan1.1panPan2
EFEMP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,389,797 - 51,396,109 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,389,824 - 51,396,107 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1849,997,510 - 50,004,619 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01852,427,071 - 52,434,176 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1852,427,841 - 52,434,176 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11851,527,128 - 51,534,242 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01851,101,501 - 51,108,618 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01851,890,821 - 51,897,925 (+)NCBIUU_Cfam_GSD_1.0
Efemp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,221,048 - 7,228,320 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365993,663,326 - 3,670,047 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365993,663,288 - 3,670,048 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EFEMP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,450,332 - 6,463,486 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,455,155 - 6,463,493 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,559,189 - 5,567,521 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EFEMP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118,384,212 - 8,391,501 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl18,385,020 - 8,390,889 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038105,673,390 - 105,680,538 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000017797   ⟹   ENSHGLP00000017622
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476720,559,795 - 20,566,341 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000017798   ⟹   ENSHGLP00000017623
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476720,560,215 - 20,565,878 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000017799   ⟹   ENSHGLP00000017624
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476720,560,215 - 20,564,777 (+)Ensembl
RefSeq Acc Id: XM_013075053   ⟹   XP_012930507
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476720,559,953 - 20,566,326 (+)NCBI
RefSeq Acc Id: XM_013075054   ⟹   XP_012930508
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476720,559,801 - 20,566,002 (+)NCBI
RefSeq Acc Id: XM_021264569   ⟹   XP_021120228
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476720,559,953 - 20,566,326 (+)NCBI
Protein Sequences
Protein RefSeqs XP_012930507 (Get FASTA)   NCBI Sequence Viewer  
  XP_012930508 (Get FASTA)   NCBI Sequence Viewer  
  XP_021120228 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04865 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017622
  ENSHGLP00000017623
  ENSHGLP00100016272
GenBank Protein JAN96657 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_012930508   ⟸   XM_013075054
- Peptide Label: isoform X2
- UniProtKB: G5B6I8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012930507   ⟸   XM_013075053
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J0H7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120228   ⟸   XM_021264569
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000017624   ⟸   ENSHGLT00000017799
RefSeq Acc Id: ENSHGLP00000017623   ⟸   ENSHGLT00000017798
RefSeq Acc Id: ENSHGLP00000017622   ⟸   ENSHGLT00000017797


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012609 Ensembl, ENTREZGENE
  ENSHGLG00100012018 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000017797 ENTREZGENE
  ENSHGLT00000017798 ENTREZGENE
  ENSHGLT00100016451 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/TrEMBL
InterPro cEGF UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
KEGG Report hgl:101711423 UniProtKB/TrEMBL
NCBI Gene Efemp2 ENTREZGENE
PANTHER EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 2 UniProtKB/TrEMBL
  EGF-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam cEGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
PRINTS THRMBOMODULN UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A0P6J0H7 ENTREZGENE, UniProtKB/TrEMBL
  G5B6I8 ENTREZGENE, UniProtKB/TrEMBL