Prdx1 (peroxiredoxin 1) - Rat Genome Database

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Gene: Prdx1 (peroxiredoxin 1) Heterocephalus glaber
Analyze
Symbol: Prdx1
Name: peroxiredoxin 1
RGD ID: 18915851
Description: ENCODES a protein that exhibits heme binding (ortholog); identical protein binding (ortholog); peroxiredoxin activity (ortholog); INVOLVED IN canonical NF-kappaB signal transduction (ortholog); erythrocyte homeostasis (ortholog); fibroblast proliferation (ortholog); ASSOCIATED WITH asbestosis (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (ortholog); euchromatin (ortholog); mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Peroxiredoxin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249061,405,253 - 1,414,926 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249061,405,253 - 1,414,980 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:23618867   PMID:30032202  


Genomics

Comparative Map Data
Prdx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249061,405,253 - 1,414,926 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249061,405,253 - 1,414,980 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PRDX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38145,511,051 - 45,522,890 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl145,510,914 - 45,542,732 (-)EnsemblGRCh38hg38GRCh38
GRCh37145,976,723 - 45,988,562 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36145,749,294 - 45,760,196 (-)NCBINCBI36Build 36hg18NCBI36
Build 34145,645,800 - 45,656,702NCBI
Celera144,260,797 - 44,271,582 (-)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef144,088,373 - 44,099,940 (-)NCBIHuRef
CHM1_1146,093,972 - 46,105,688 (-)NCBICHM1_1
T2T-CHM13v2.0145,383,419 - 45,395,258 (-)NCBIT2T-CHM13v2.0
Prdx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394116,542,796 - 116,557,196 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4116,542,741 - 116,558,019 (+)EnsemblGRCm39 Ensembl
GRCm384116,685,599 - 116,700,000 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,685,544 - 116,700,822 (+)EnsemblGRCm38mm10GRCm38
MGSCv374116,358,204 - 116,372,605 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364116,183,531 - 116,197,932 (+)NCBIMGSCv36mm8
Celera4115,419,593 - 115,433,994 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.28NCBI
Prdx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85135,383,906 - 135,399,504 (+)NCBIGRCr8
mRatBN7.25130,147,258 - 130,162,856 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5130,147,204 - 130,162,856 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5132,772,005 - 132,788,840 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05134,526,605 - 134,543,441 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05134,549,011 - 134,565,848 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05135,536,413 - 135,551,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,536,413 - 135,551,990 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05139,332,556 - 139,348,210 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45136,975,780 - 136,991,630 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15136,981,005 - 136,996,856 (+)NCBI
Celera5128,674,439 - 128,690,018 (+)NCBICelera
Cytogenetic Map5q35NCBI
Prdx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546412,761,401 - 12,773,146 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546412,761,390 - 12,773,413 (+)NCBIChiLan1.0ChiLan1.0
PRDX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21181,286,968 - 181,297,925 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11180,428,500 - 180,439,413 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,813,508 - 44,824,430 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1146,171,453 - 46,182,018 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl146,171,453 - 46,182,018 (-)Ensemblpanpan1.1panPan2
PRDX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11514,834,009 - 14,855,665 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1514,838,652 - 14,862,971 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1514,959,792 - 14,976,803 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01514,988,879 - 15,010,844 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,993,508 - 15,018,355 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,790,828 - 14,808,277 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01514,858,579 - 14,875,829 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01514,930,831 - 14,947,857 (+)NCBIUU_Cfam_GSD_1.0
Prdx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505860,816,994 - 60,828,561 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647426,639,259 - 26,653,328 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647426,641,776 - 26,653,291 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRDX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6165,824,395 - 165,861,442 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16165,847,390 - 165,859,918 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26153,253,841 - 153,265,947 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRDX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12087,267,026 - 87,277,634 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2087,267,044 - 87,279,978 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603329,683,931 - 29,694,719 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000001778   ⟹   ENSHGLP00000001733
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249061,405,253 - 1,414,926 (-)Ensembl
RefSeq Acc Id: XM_004872929   ⟹   XP_004872986
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249061,405,253 - 1,414,980 (-)NCBI
RefSeq Acc Id: XM_013068549   ⟹   XP_012924003
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249061,405,253 - 1,414,941 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004872986 (Get FASTA)   NCBI Sequence Viewer  
  XP_012924003 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99750 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000001733
  ENSHGLP00100032468
GenBank Protein JAO03357 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004872986   ⟸   XM_004872929
- UniProtKB: G5ARW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012924003   ⟸   XM_013068549
- UniProtKB: G5ARW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000001733   ⟸   ENSHGLT00000001778


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001318 Ensembl, ENTREZGENE
  ENSHGLG00100050016 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000001778 ENTREZGENE
  ENSHGLT00100047983 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro AhpC/TSA UniProtKB/TrEMBL
  Peroxiredoxin_AhpC-typ UniProtKB/TrEMBL
  Peroxiredoxin_C UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/TrEMBL
KEGG Report hgl:101709755 UniProtKB/TrEMBL
NCBI Gene Prdx1 ENTREZGENE
PANTHER PEROXIREDOXIN-1 UniProtKB/TrEMBL
  THIOREDOXIN PEROXIDASE UniProtKB/TrEMBL
Pfam 1-cysPrx_C UniProtKB/TrEMBL
  AhpC-TSA UniProtKB/TrEMBL
PIRSF AHPC UniProtKB/TrEMBL
PROSITE THIOREDOXIN_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt G5ARW1 ENTREZGENE, UniProtKB/TrEMBL