Cdc42ep3 (CDC42 effector protein 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Cdc42ep3 (CDC42 effector protein 3) Heterocephalus glaber
Analyze
Symbol: Cdc42ep3
Name: CDC42 effector protein 3
RGD ID: 18915525
Description: ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN positive regulation of actin filament polymerization (inferred); positive regulation of pseudopodium assembly (inferred); regulation of cell shape (inferred); ASSOCIATED WITH RASopathy (ortholog); FOUND IN actin cytoskeleton (inferred); cytoplasm (inferred); endomembrane system (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473819,269,266 - 19,291,334 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473819,268,332 - 19,291,355 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
RASopathy  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625  


Genomics

Comparative Map Data
Cdc42ep3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473819,269,266 - 19,291,334 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473819,268,332 - 19,291,355 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CDC42EP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38237,641,944 - 37,672,949 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl237,641,882 - 37,738,468 (-)EnsemblGRCh38hg38GRCh38
GRCh37237,869,087 - 37,900,092 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36237,724,247 - 37,752,830 (-)NCBINCBI36Build 36hg18NCBI36
Build 34237,782,393 - 37,810,977NCBI
Celera237,711,639 - 37,740,219 (-)NCBICelera
Cytogenetic Map2p22.2NCBI
HuRef237,608,843 - 37,639,483 (-)NCBIHuRef
CHM1_1237,798,478 - 37,829,103 (-)NCBICHM1_1
T2T-CHM13v2.0237,648,900 - 37,679,907 (-)NCBIT2T-CHM13v2.0
Cdc42ep3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391779,641,152 - 79,662,520 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1779,641,156 - 79,662,520 (-)EnsemblGRCm39 Ensembl
GRCm381779,333,723 - 79,355,091 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1779,333,727 - 79,355,091 (-)EnsemblGRCm38mm10GRCm38
MGSCv371779,733,365 - 79,754,431 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361779,239,083 - 79,260,138 (-)NCBIMGSCv36mm8
Celera1783,643,319 - 83,664,470 (-)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1750.3NCBI
Cdc42ep3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8621,463,081 - 21,483,553 (+)NCBIGRCr8
mRatBN7.2615,710,894 - 15,731,366 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl615,708,730 - 15,732,721 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx616,009,294 - 16,029,787 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0616,331,501 - 16,352,000 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0615,827,760 - 15,848,253 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.061,922,500 - 1,942,972 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl61,922,500 - 1,942,972 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.061,912,346 - 1,932,818 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.462,111,458 - 2,132,242 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.162,111,145 - 2,132,242 (-)NCBI
Celera615,376,813 - 15,397,267 (+)NCBICelera
Cytogenetic Map6q12NCBI
Cdc42ep3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554415,437,626 - 5,461,085 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554415,437,626 - 5,461,085 (-)NCBIChiLan1.0ChiLan1.0
CDC42EP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21288,810,902 - 88,841,486 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A88,809,369 - 88,845,460 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A37,665,482 - 37,696,817 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A38,429,213 - 38,460,283 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A38,433,075 - 38,433,839 (-)Ensemblpanpan1.1panPan2
CDC42EP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11729,949,452 - 29,973,008 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1729,950,210 - 29,973,008 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1729,763,162 - 29,786,805 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01730,599,265 - 30,622,939 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1730,599,304 - 30,603,875 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11729,825,858 - 29,849,497 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01729,892,669 - 29,916,277 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01730,107,873 - 30,131,523 (-)NCBIUU_Cfam_GSD_1.0
Cdc42ep3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629242,012,013 - 42,035,924 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936663678,469 - 701,416 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936663676,869 - 701,416 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC42EP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3102,538,586 - 102,567,796 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13102,537,662 - 102,567,669 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23108,935,436 - 108,959,926 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDC42EP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11469,709,470 - 69,738,305 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1469,736,558 - 69,737,322 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604542,215,427 - 42,246,548 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000026546   ⟹   ENSHGLP00000026311
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473819,269,266 - 19,291,334 (-)Ensembl
RefSeq Acc Id: XM_004839304   ⟹   XP_004839361
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473819,268,332 - 19,291,355 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004839361 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB14598 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000026311
  ENSHGLP00000053784
  ENSHGLP00000055106
  ENSHGLP00000055279
GenBank Protein JAN96425 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004839361   ⟸   XM_004839304
- UniProtKB: G5BZ87 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000026311   ⟸   ENSHGLT00000026546


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018723 Ensembl, ENTREZGENE
  ENSHGLG00000038853 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000026546 ENTREZGENE
  ENSHGLT00000062852 UniProtKB/TrEMBL
  ENSHGLT00000078028 UniProtKB/TrEMBL
  ENSHGLT00000081010 UniProtKB/TrEMBL
InterPro Cdc42_effect UniProtKB/TrEMBL
  CRIB_dom UniProtKB/TrEMBL
KEGG Report hgl:101698553 UniProtKB/TrEMBL
NCBI Gene Cdc42ep3 ENTREZGENE
PANTHER CDC42 EFFECTOR PROTEIN 3 UniProtKB/TrEMBL
  CDC42 EFFECTOR PROTEIN BORG UniProtKB/TrEMBL
Pfam BORG_CEP UniProtKB/TrEMBL
  PBD UniProtKB/TrEMBL
PROSITE CRIB UniProtKB/TrEMBL
SMART PBD UniProtKB/TrEMBL
UniProt G5BZ87 ENTREZGENE, UniProtKB/TrEMBL